全文获取类型
收费全文 | 3153020篇 |
免费 | 247749篇 |
国内免费 | 5647篇 |
专业分类
耳鼻咽喉 | 45751篇 |
儿科学 | 101351篇 |
妇产科学 | 85103篇 |
基础医学 | 445568篇 |
口腔科学 | 89848篇 |
临床医学 | 286418篇 |
内科学 | 613988篇 |
皮肤病学 | 65675篇 |
神经病学 | 260427篇 |
特种医学 | 125595篇 |
外国民族医学 | 1301篇 |
外科学 | 476391篇 |
综合类 | 74106篇 |
现状与发展 | 2篇 |
一般理论 | 1236篇 |
预防医学 | 252389篇 |
眼科学 | 73754篇 |
药学 | 235849篇 |
6篇 | |
中国医学 | 5946篇 |
肿瘤学 | 165712篇 |
出版年
2018年 | 32460篇 |
2017年 | 24864篇 |
2016年 | 27429篇 |
2015年 | 30970篇 |
2014年 | 44293篇 |
2013年 | 67560篇 |
2012年 | 91735篇 |
2011年 | 97081篇 |
2010年 | 57371篇 |
2009年 | 54823篇 |
2008年 | 92227篇 |
2007年 | 98339篇 |
2006年 | 98989篇 |
2005年 | 96314篇 |
2004年 | 93205篇 |
2003年 | 90213篇 |
2002年 | 88666篇 |
2001年 | 145966篇 |
2000年 | 151161篇 |
1999年 | 128137篇 |
1998年 | 37085篇 |
1997年 | 33617篇 |
1996年 | 33481篇 |
1995年 | 32293篇 |
1994年 | 30265篇 |
1993年 | 28271篇 |
1992年 | 103076篇 |
1991年 | 100169篇 |
1990年 | 96788篇 |
1989年 | 93191篇 |
1988年 | 86302篇 |
1987年 | 85033篇 |
1986年 | 80254篇 |
1985年 | 76770篇 |
1984年 | 58216篇 |
1983年 | 49549篇 |
1982年 | 29813篇 |
1981年 | 26751篇 |
1979年 | 54228篇 |
1978年 | 37978篇 |
1977年 | 32135篇 |
1976年 | 30200篇 |
1975年 | 32100篇 |
1974年 | 39132篇 |
1973年 | 37292篇 |
1972年 | 34768篇 |
1971年 | 31994篇 |
1970年 | 30294篇 |
1969年 | 28030篇 |
1968年 | 25526篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
991.
Esophageal pH monitoring is the accepted standard for the investigation of gastroesophageal reflux (GER) in adults. A postal questionnaire was sent to 912 United Kingdom paediatric physicians & surgeons. Five hundred forty-seven (61%) replied, with 124 (22.7%) currently using the technique, mostly in conjunction with barium swallow and/or esophagoscopy. The use of pH monitoring to quantify GER was also accepted in principal as being the best determinant of reflux by a further 186 (34%), but as yet was unavailable in their hospitals. Pediatricians were also questioned as to their management of children with GER. The majority were treated medically with a variety of antireflux medication, with only 237 (42%) referring cases for surgery. 相似文献
992.
993.
994.
P M Doraiswamy K R Krishnan O B Boyko M M Husain G S Figiel V J Palese P R Escalona S A Shah W M McDonald W J Rockwell 《Progress in neuro-psychopharmacology & biological psychiatry》1991,15(3):351-356
1. The frequent occurrence of hypothalamo-pituitary dysfunction in patients with eating disorders as well as prior reports that nutritional and endocrine status influence pituitary morphology, led us to hypothesize that pituitary size and shape may be altered in patients with eating disorders. 2. Magnetic resonance imaging (MRI) does not use ionizing radiation and is currently one of the most feasible modalities available to study the pituitary gland in vivo. Using MRI, we have previously reported in a preliminary study that female patients with eating disorders had significantly smaller pituitary glands than controls. In addition MRI excluded any pituitary mass lesions. 3. In this report, we confirm our previous MRI findings and provide further evidence of pituitary abnormalities in an expanded sample of eating disorder patients. Preliminary data on pituitary volume estimates from MRI scans are provided for a subset of patients and controls. 相似文献
995.
J R Glowa J D Bacher M Herkenham P W Gold 《Progress in neuro-psychopharmacology & biological psychiatry》1991,15(3):379-391
1. Rhesus monkeys were equipped with a novel intracerebroventricular (i.c.v.) cannula system and trained to respond under operant schedules of food presentation or termination of stimuli associated with the delivery of shock (escape). 2. CRH decreased food-maintained behavior in a dose-related manner over the range of (0.3-10 micrograms/kg) but did not affect escape responding, demonstrating a selective effect on food-maintained responding. 3. This selective effect was related to the tendency for responding to stop after delivery of a food pellet when higher doses of CRH were given, consistent with the notion that a conditioned aversion to food was established in the presence of CRH. 4. This may suggest that in hyperaroused clinical states such as depression and anorexia nervosa, focus is shifted away from appetitive tasks as a result of increased levels of CRH. 相似文献
996.
S. T. F. M. Frequin F. J. M. Gabreë ls A. A. W. M. Gabreë ls-Festen E. M. G. Joosten 《Clinical neurology and neurosurgery》1991,93(4):323-326
A girl of 14 year is presented with a distal spinal muscular atrophy (SMA) with autosomal recessive inheritance. The technical findings are in agreement with the diagnosis. Light microscopical examination of sural nerve biopsy, including teased fiber studies and morphometry, showed no abnormalities. Electron microscopical investigation however demonstrated axonal pathology. The question arises if distal SMA is a distal axonopathy mainly of motor nerves, but to some extent also of sensory nerves. 相似文献
997.
Permissive herpes simplex virus (HSV) infection in tissue culture results in host cell destruction. Latent HSV infection in vivo occurs in neurons of peripheral sensory ganglia (PSG) and it therefore can not take place in neurons in which the virus has completed a lytic replication cycle similar to that present in vitro. Our hypothesis, based on experimental data and observations in humans, suggests that establishment of latent infection and reactivation of HSV-1 does not involve neuronal cell loss. Latency is established in neurons in which the virus does not replicate and is determined, in part, by the tissue levels of a herpes transactivating protein (Vmw65) that is a component of the viral tegument. We also suggest that reactivation of latent infection does not involve destruction of neurons and is due to replication of virus at the peripheral mucocutaneous tissues to where virus or viral DNA have been transported from the nervous tissue. Alternatively, reactivation is initiated in the PSG using a replication cycle which does not involve irreversible damage to neurons. This model explains the lack of damage to neurons which continue to serve as permanent reservoirs of latent virus for the entire life of the host. 相似文献
998.
Atheromatous lesions of the proximal vertebral artery and the subclavian artery may lead to ischaemic manifestations, occasionally with severe consequences in the vertebro-basilar territory. These transient ischaemic attacks are most often caused by haemodynamic insufficiency rather than thrombo-embolic complications addressed by anticoagulant and antiaggregant treatments. In this study, 8 cases of vertebro-basilar ischaemia (VBI), secondary to subclavian and proximal vertebral artery lesions, are reported. Surgical techniques, subclavian-to-subclavian artery by-pass (5 cases) and vertebral to common carotid artery transposition (3 cases) are described with their respective results. Through a review of the literature, the various operative modalities are discussed in the different pathological conditions of the proximal extracranial vertebro-basilar disease. It appears that the subclavian to subclavian artery by-pass as well as the vertebral-to-common carotid artery transposition are safe surgical procedures with strikingly low morbidity and mortality rates. The widely achieved relief of the ischaemic episodes, undoubtedly makes this surgery an alternative to medical treatment. 相似文献
999.
1000.