全文获取类型
收费全文 | 15903篇 |
免费 | 1127篇 |
国内免费 | 73篇 |
专业分类
耳鼻咽喉 | 185篇 |
儿科学 | 444篇 |
妇产科学 | 333篇 |
基础医学 | 2196篇 |
口腔科学 | 377篇 |
临床医学 | 1400篇 |
内科学 | 3679篇 |
皮肤病学 | 615篇 |
神经病学 | 1528篇 |
特种医学 | 374篇 |
外科学 | 1582篇 |
综合类 | 73篇 |
现状与发展 | 1篇 |
一般理论 | 4篇 |
预防医学 | 1814篇 |
眼科学 | 318篇 |
药学 | 1037篇 |
中国医学 | 65篇 |
肿瘤学 | 1078篇 |
出版年
2024年 | 10篇 |
2023年 | 198篇 |
2022年 | 316篇 |
2021年 | 840篇 |
2020年 | 397篇 |
2019年 | 779篇 |
2018年 | 971篇 |
2017年 | 541篇 |
2016年 | 520篇 |
2015年 | 594篇 |
2014年 | 797篇 |
2013年 | 1102篇 |
2012年 | 1517篇 |
2011年 | 1502篇 |
2010年 | 939篇 |
2009年 | 685篇 |
2008年 | 812篇 |
2007年 | 757篇 |
2006年 | 680篇 |
2005年 | 680篇 |
2004年 | 571篇 |
2003年 | 525篇 |
2002年 | 473篇 |
2001年 | 95篇 |
2000年 | 43篇 |
1999年 | 94篇 |
1998年 | 95篇 |
1997年 | 83篇 |
1996年 | 76篇 |
1995年 | 52篇 |
1994年 | 29篇 |
1993年 | 41篇 |
1992年 | 28篇 |
1991年 | 22篇 |
1990年 | 17篇 |
1989年 | 8篇 |
1988年 | 13篇 |
1987年 | 8篇 |
1986年 | 10篇 |
1985年 | 8篇 |
1984年 | 18篇 |
1983年 | 15篇 |
1982年 | 8篇 |
1981年 | 11篇 |
1980年 | 10篇 |
1979年 | 7篇 |
1978年 | 12篇 |
1977年 | 8篇 |
1976年 | 6篇 |
1974年 | 6篇 |
排序方式: 共有10000条查询结果,搜索用时 334 毫秒
41.
The smoking control policies recommended by the World Health Organisation have achieved a slight decrease in smoking prevalence in developed countries, although associated mortality is still very high. The use of tobacco products other than cigarettes and even medicinal nicotine (known as nicotine replacement therapy [NRT]) has been proposed as a risk reduction strategy. Among the tobacco products with less individual risk than cigarettes would be any type of tobacco without smoke (smokeless) with a low content in nitrosamines and modified cigarettes; both forms included under the PREP (Potentially Reduced Exposure Products) concept. The idea would be to promote these products among patients who cannot quit smoking or wish to reduce their risk without giving up nicotine intake. The possible effects of risk reduction strategies, including PREP, on the decreased prevalence and morbidity and mortality are reviewed, and the possible implications that this measure could have in Spain are analysed. Tobacco control measures in Spain have only been made recently and are still insufficient. Therefore, the current priority in Spain is to develop control policies that have proven to be more than effective. The marketing and advertising of new tobacco products, even with reduced potential risk, seems more a serious threat than an opportunity for developing smoking control policies. 相似文献
42.
Mario Sénéchal Isabelle Lemieux Isabel Beucler Gerard Drobinski Sylvie Cormont Michelle Dubois Iradj Gandjbakhch Jean-Pierre Després Richard Dorent 《The Journal of heart and lung transplantation》2005,24(7):819-826
BACKGROUND: This study evaluated the prevalence of the atherogenic metabolic triad and the hypothesis that waist circumference and fasting triglyceride concentrations could be used as screening tools for identification of the atherogenic metabolic triad in a population of heart transplant men. It also evaluated the relationship between the atherogenic metabolic triad and coronary artery disease (CAD). METHODS: In the study group of 83 consecutive male heart transplant patients having their routine annual coronarography, 23 patients (28%) were characterized by the atherogenic metabolic triad defined by the presence of elevated fasting insulin and apolipoprotein B concentrations and by small low-density lipoprotein (LDL) particles. RESULTS: Seventy-seven per cent of patients with waist circumference values >/= 90 cm and with elevated triglyceride levels (>/=2.0 mmol/liter) were characterized by this atherogenic metabolic triad. Patients with the atherogenic metabolic triad were at markedly increased risk of CAD (odds ratio of 25.3, 95% CI: 1.11-577.3, p < 0.04) compared to heart transplant patients without the atherogenic metabolic triad. CONCLUSIONS: About 30% of heart transplant patients showed the features of the atherogenic metabolic triad. Measurement and interpretation of waist circumference and fasting triglycerides could be used among heart transplant patients to early identify men characterized by the presence of elevated fasting insulin and apolipoprotein B concentrations and small LDL particles. The presence of the atherogenic metabolic triad identified patients at high risk of CAD even in the heart transplant population. 相似文献
43.
Luís Mariano Isabel Vila?a Jorge Almeida Mota Garcia Maria Júlia Maciel 《Revista portuguesa de cardiologia》2007,26(3):265-270
Apical ballooning is a novel clinical entity reported in different contexts of physical and psychological stress, which is more common in middle-aged women. Of unknown etiology, the syndrome is characterized by a sudden and transient dilatation of the left ventricular apex in the absence of obstructive atherosclerotic coronary disease or evidence of myocardial necrosis, with total late recovery of ventricular function. The authors report the case of a 53-year-old woman who was admitted to the emergency room with left arm ischemia and low cardiac output, requiring ventilatory support. Left catheterization showed typical medial and apical myocardial dysfunction, with normal coronary arteries. Transesophageal echocardiography revealed a thrombus attached to the lower face of the aortic arch, which probably explained the thromboembolism of the arm but was unlikely to be the cause of the left ventricular dysfunction since there were no enzymatic or electrocardiographic signs of myocardial necrosis and normal wall motion was fully recovered. 相似文献
44.
45.
46.
Ana Berta Sousa Ana Medeira Binita M Kamath Nancy B Spinner Isabel Cordeiro 《Revista portuguesa de cardiologia》2006,25(4):447-452
Although most congenital heart defects are isolated abnormalities of embryonic development, with little genetic contribution, a small number are components of syndromes. In such cases, an accurate diagnosis has important implications for individual prognosis and familial genetic counseling. Alagille syndrome (AGS) is a dominantly inherited multisystem developmental disorder, which primarily affects the liver, heart, eyes, skeleton, and face. In recent years, the identification of the AGS gene has drawn attention to the existence of subclinical carriers, and broadened the spectrum of phenotypical variation associated with this syndrome. The authors present a case of mother and son with benign stenosis of the pulmonary artery branches. Subtle facial aspects suggested the diagnosis of AGS, which was confirmed by molecular analysis. Relevant clinical investigations and diagnostic implications are discussed. 相似文献
47.
Andreia Coroas José G G de Oliveira Susana Sampaio Cátia Borges Isabel Tavares Manuel Pestana Maria D V de Almeida 《Journal of renal nutrition》2004,14(3):157-163
OBJECTIVE: Kidney transplantation restores renal filtration, although it does not achieve the function of 2 native kidneys, and with time it may involute back to chronic renal failure. We hypothesized that bioelectrical impedance analysis (BIA) might highlight differences for body compartments among kidney transplants (Tx) with different filtration rates. METHODS: Thirty transplantation patients (19 male, 11 female) were studied at 62.4+/-26.6 months postsurgery and were divided into 3 groups: good creatinine clearance (crCl, mL/min/1.73 m2; >65.0), borderline (35.0相似文献
48.
To examine the role of complement in certain autoimmune neuromuscular diseases, we used an in-vitro quantitative complement uptake assay that allows measurement of the capacity of patients' sera to deposit fragments of the third complement component onto sensitized targets. C3 uptake was significantly higher in patients with active dermatomyositis, Guillain-Barré syndrome and myasthenia gravis, compared to inclusion body myositis and controls. The in-vitro C3 uptake assay supports the role of C3b neoantigen and Membranolytic Attack Complex deposition in the target tissues and may be a useful tool to monitor disease activity in patients with complement-mediated neurological disorders. 相似文献
49.
Summary Results of re-operations of 99 adult patients with recurrent supratentorial lobar glioblastomas (60 patients) and anaplastic
astrocytomas (39 patients) have been reviewed. In all cases both surgical interventions were performed at the same institute.
Age of patients with glioblastoma varied between 19 and 64 and with anaplastic astrocytoma between 21 and 68 years, with a
mean value of 48 and 36 years, respectively. The median interval between the first and second operations was 47 weeks for
patients with glioblastoma and 83 weeks with anaplastic astrocytoma. The mortality rate of the re-operations was 3%. Following
re-operation radio-and/or chemotherapy was applied in most of the cases. Median survival time after re-operation was 18.5
weeks in patients with glioblastoma and 55 weeks with anaplastic astrocytoma. Survival curves were calculated according to
Kaplan-Meier method and for statistical evaluation the generalized Wilcoxon test and multiple linear regression method were
used.
Histologically lower grade tumour at the first operation and longer interval between the two operations proved to influence
positively and differentiation of the primary tumour negatively the survival time. 相似文献
50.
Alex Iranzo Esteban Mu?oz Joan Santamaria Isabel Vilaseca Montserrat Milà Eduardo Tolosa 《Movement disorders》2003,18(10):1179-1183
We evaluated the occurrence of REM sleep behaviour disorder (RBD) and vocal cord abductor paralysis (VCAP) in a group of 9 Machado-Joseph disease (MJD) patients. RBD was diagnosed by clinical history plus audiovisual polysomnography in 4 men and 1 woman (55%). While dreaming, 4 fell out of the bed and the other injured his arms. Laryngoscopy detected bilateral VCAP in 1 patient with stridor who required emergency tracheotomy, and partial vocal cord abductor restriction in 2. RBD and VCAP are two potentially injurious conditions that should be considered part of the clinical spectrum of MJD. 相似文献