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91.
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93.
Sandra Mndez Clara Barba Alisa Roddick Lanzilotta Rob Kelly Jose Luís Parra Luísa Coderch 《Skin research and technology》2008,14(4):448-453
Purpose: Hair lipids can contribute to physicochemical phenomena such as diffusion, cell cohesion and mechanical strength, although lipids occur at much lower levels (1–6% dry weight) than proteins (>90%).Hair lipids can be diminished by hair washing and submission to chemical treatments. Studies have shown that internal wool lipids (IWL) resemble those membranes of other keratinic tissues such as human hair or stratum corneum. Results: In this work, the IWL, in the form of liposomes or from an emulsion system, were applied to untreated hair fibres and also treated hair fibres. The results showed that application of IWL to pretreated hair samples lead to an improvement in mechanical strength properties of the fibres when the IWL were applied structured as liposomes. Differential scanning calorimetry studies demonstrated that the application of IWL to pretreated hair sample led to a slight increase in the crystalline material of the fibres. Moreover, scanning electron microscopy studies showed that application of IWL liposomes to damaged hair fibres lead to an improvement of the cuticle scale, demonstrating the importance of the use of a delivery vehicle with a bilayer structure similar to the one present in the hair fibre to restore the natural properties of the fibre. 相似文献
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Influence of exercise rehabilitation on myocardial perfusion and sympathetic heart innervation in ischaemic heart disease 总被引:2,自引:2,他引:0
Montserrat Estorch Albert Flotats Ricard Serra-Grima Carina Marí Teresa Prat Joan Carles Martín Lluís Bernà Ana María Catafau Ana Tembl Ignasi Carrió 《European journal of nuclear medicine and molecular imaging》2000,27(3):333-339
Exercise rehabilitation improves the clinical status in ischaemic heart disease. The purpose of this study was to assess the
influence of exercise rehabilitation on myocardial perfusion and sympathetic heart innervation. Sixteen patients with ischaemic
heart disease and previous myocardial infarction were investigated by means of exercise/rest tetrofosmin and metaiodobenzylguanidine
(MIBG) exercise/rest single-photon emission tomography (SPET) studies, before and 6 months after starting an exercise rehabilitation
programme. Tomograms were divided into 15 segments, and these were grouped into five myocardial anatomical regions. Regional
uptake of both tracerswas quantified and expressed as a percentage of maximumpeak activity. The percentage ≤55% was chosen
to evaluate defect size, and the results were expressed as a percentage of left ventricular mass. Areas with perfused and
denervated myocardium and areas with ischaemic myocardium were calculated. In addition, regions with <75% of peak activity
in the exercise perfusion study at baseline were divided into two groups according to whether there was an increase in peak
activity of >10% (representing reversible regional defects) or an increase of <10% (representing fixed regional defects) in
the rest study. These percentages were compared with the percentages obtained in the innervation study, and with the percentages
obtained in exercise/rest perfusion and innervation studies performed 6 months after starting rehabilitation. Myocardial perfusion
defects were significantly smaller than myocardial innervation defects before and 6 months after starting exercise rehabilitation.
The area of ischaemia 6 months after starting exercise rehabilitation was significantly smaller than that before rehabilitation
(0.31%± 1.4% vs 1.4%±1.6%, P<0.01). The size of innervation defects and the area of perfused and denervated myocardium did not show significant differences
between the two studies performed before and 6 months after starting exercise rehabilitation. In reversible regional defects
the percentage of peak activity was significantly increased 6 months after starting exercise rehabilitation in exercise and
rest studies (P<0.001), while in fixed regional defects it was significantly increased only in exercise studies (P<0.001). There was no significant change in the regional MIBG percentages. We conclude that in ischaemic heart disease, exercise
rehabilitation over a period of 6 months improves myocardial perfusion, but does not cause changes in sympathetic myocardial
innervation.
Received 12 August and in revised form 17 November 1999 相似文献
96.
S Esposito D Galante D Barba C Pennucci D Limauro 《Drugs under experimental and clinical research》1986,12(4):329-333
A total of 343 Gram-negative bacteria were isolated and identified from urine specimens of patients with urinary tract infections. All the bacteria were investigated for their production of beta-lactamases by the nitrocefin test. beta-lactamase-producing strains were tested by the Datta method to detect any transfer of beta-lactamase production to a receiving E. coli K12 RN-strain. MICs of six beta-lactamase-stable compounds (ceftazidime, ceftriaxone, cefamandole, cefoxitin, cefotaxime, cefuroxime) were determined against all the beta-lactamase transferring bacteria and their respective transconjugants by a miniaturized dilution broth method. beta-lactamases produced by donors and transconjugants were purified and identified by determination of the isoelectric point by focusing; their hydrolytic activity was assessed by a spectrophotometric method using cytochrome c reduction. A total of 129 bacteria out of 343 produced beta-lactamases and 27 of these transferred the beta-lactamase production by conjugation. The beta-lactamases isolated from donors and transconjugants had the same pl and the same substrate profile. Ceftazidime was more stable to all the beta-lactamases isolated and more active against all the bacteria examined than the other compounds. 相似文献
97.
Alegret JM Palazón O Duran I Vernis JM 《The international journal of cardiovascular imaging》2005,21(2-3):213-217
Objective:To assess the utility of transthoracic echocardiography (TTE) with second harmonic combined with transesophageal echocardiography (TEE) in defining aortic valve morphology in a subset of patients with a high prevalence of bicuspid aortic valve. Methods and Materials: Patients (n=174) with dilated aortic root were consecutively evaluated using, initially, TTE. The aortic valve structure was assigned as tricuspid, bicuspid or undefined. In those assigned as bicuspid or undefined, TEE was performed. Other factors that could affect valve morphology assignment were recorded and evaluated in multivariate analysis. Results: TTE was able to characterise 89% of the tricuspid valves and 56% of the bicuspid. Bicuspid structure was the only variable that, in the multivariate analysis, was related to the inability to definitively assign aortic valve morphology (OR=0.13). TEE was performed in 59 patients and the morphology was definitively assigned in 56 of them (95%). TEE diagnosed 15 bicuspid valves in addition to confirming the 17 identified by TTE. Overall, using TTE combined with TEE we were able to correctly assign valvular morphology in 98% of patients. Conclusion: In a subset of patients with a high prevalence of bicuspid aortic valve, combination of TTE and TEE should be considered to define aortic valve morphology. TEE identifies an important number of patients with BAV. 相似文献
98.
99.
Symptomatic and presumed symptomatic focal epilepsies in childhood: An observational,prospective multicentre study
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Marilena Vecchi Carmen Barba Debora De Carlo Micol Stivala Renzo Guerrini Emilio Albamonte Domiziana Ranalli Domenica Battaglia Giada Lunardi Clementina Boniver Benedetta Piccolo Francesco Pisani Gaetano Cantalupo Giuliana Nieddu Susanna Casellato Silvia Cappanera Elisabetta Cesaroni Nelia Zamponi Domenico Serino Lucia Fusco Alessandro Iodice Filippo Palestra Lucio Giordano Elena Freri Ilaria De Giorgi Francesca Ragona Tiziana Granata Isabella Fiocchi Stefania Maria Bova Massimo Mastrangelo Alberto Verrotti Sara Matricardi Elena Fontana Davide Caputo Francesca Darra Bernardo Dalla Bernardina Francesca Beccaria Giuseppe Capovilla Maria Pia Baglietto Alessandra Gagliardi Aglaia Vignoli Maria Paola Canevini Egle Perissinotto Stefano Francione 《Epilepsia》2016,57(11):1808-1816
100.
Barba J Edwards 《AORN journal》1976,24(5):841-842