全文获取类型
收费全文 | 429篇 |
免费 | 16篇 |
国内免费 | 1篇 |
专业分类
耳鼻咽喉 | 2篇 |
儿科学 | 25篇 |
妇产科学 | 6篇 |
基础医学 | 50篇 |
口腔科学 | 4篇 |
临床医学 | 42篇 |
内科学 | 116篇 |
皮肤病学 | 13篇 |
神经病学 | 26篇 |
特种医学 | 1篇 |
外科学 | 96篇 |
综合类 | 3篇 |
预防医学 | 7篇 |
眼科学 | 2篇 |
药学 | 18篇 |
肿瘤学 | 35篇 |
出版年
2022年 | 9篇 |
2021年 | 7篇 |
2018年 | 2篇 |
2017年 | 2篇 |
2016年 | 4篇 |
2015年 | 11篇 |
2014年 | 16篇 |
2013年 | 4篇 |
2012年 | 6篇 |
2010年 | 8篇 |
2009年 | 6篇 |
2008年 | 6篇 |
2007年 | 7篇 |
2006年 | 21篇 |
2005年 | 7篇 |
2004年 | 8篇 |
2003年 | 9篇 |
2002年 | 8篇 |
2001年 | 7篇 |
2000年 | 2篇 |
1999年 | 10篇 |
1998年 | 21篇 |
1997年 | 16篇 |
1996年 | 26篇 |
1995年 | 28篇 |
1994年 | 23篇 |
1993年 | 13篇 |
1992年 | 7篇 |
1991年 | 6篇 |
1990年 | 2篇 |
1989年 | 3篇 |
1987年 | 2篇 |
1986年 | 5篇 |
1983年 | 6篇 |
1982年 | 3篇 |
1981年 | 5篇 |
1980年 | 2篇 |
1979年 | 2篇 |
1978年 | 5篇 |
1977年 | 2篇 |
1976年 | 2篇 |
1975年 | 2篇 |
1959年 | 5篇 |
1958年 | 13篇 |
1957年 | 17篇 |
1956年 | 24篇 |
1955年 | 17篇 |
1954年 | 15篇 |
1949年 | 1篇 |
1948年 | 1篇 |
排序方式: 共有446条查询结果,搜索用时 15 毫秒
91.
H. SAITO R. OGONUKI A. YANADORI S. YAMAZAKI M. NAGAI 《The British journal of dermatology》1994,130(2):235-237
Summary We report a 3-year-old girl with a congenital dermal sinus associated with an intracranial dermoid cyst. 相似文献
92.
HYPERMINERALOCORTICISM WITHOUT ELEVATION OF PLASMA ALDOSTERONE: DEOXYCORTICOSTERONE-PRODUCING ADRENAL ADENOMA AND HYPERPLASIA 总被引:2,自引:0,他引:2
SAN-E ISHIKAWA TOSHIKAZU SAITO KENZO KANEKO KOJI OKADA SHUICHI FUKUDA TAKESHI KUZUYA 《Clinical endocrinology》1988,29(4):367-375
Two female patients were admitted for evaluation of hypertension and hypokalaemia. Plasma renin activity was suppressed and plasma aldosterone levels were within the normal value in a 52-year-old woman and below the normal value in the other patient, a 62-year-old woman. Plasma 11-deoxycorticosterone (DOC) levels were as high as 1.13 and 1.47 nmol/l, respectively. Adrenal scintigram and abdominal CT scan clearly showed a right adrenal tumour in the 52-year-old woman. After adrenalectomy plasma DOC level decreased to the normal level of 0.12 nmol/l, and her blood pressure and serum potassium became normal. Abdominal CT scan revealed no finding of adrenal tumour in the older woman. These results indicate that these two patients had hypermineralocorticism with elevation of plasma DOC. One patient had a DOC-producing adrenal adenoma, and the other probably had bilateral adrenal hyperplasia. 相似文献
93.
HIDEO SAKAMOTO KATSUYUKI SAITO TAKESHI SHICHIZYO KIMIYASU ISHIKAWA ATUSHI IGARASHI HIDEKI YOSHIDA 《International journal of urology》2006,13(8):1073-1078
AIM: We assessed the value of scrotal color Doppler ultrasonography as a routine examination in infertile men. METHODS: Color Doppler ultrasonography was performed in 545 infertile men with a mean age of 35.8 years to detect intrascrotal abnormalities. Findings were compared with those of physical examination. RESULTS: Intrascrotal abnormalities were detected by ultrasonography in 65.3% of patients. Of 374 abnormalities, 58.3% were undetected by physical examination. Left varicocele was found in 313 patients (57.4%); testicular microlithiasis in 30 (5.5%); epididymal cyst in 21 (3.9%); right varicocele in 4 (0.8%); and testicular cysts in 3 (0.6%). One occurrence each (0.2%) was found for testicular tumor, intrascrotal hemangioma, and hydrocele of the spermatic cord. Compared to ultrasonography, sensitivity in detecting left varicocele by physical examination was 58.4%; specificity, 79.3%; accuracy, 67.3%; and positive predictive value, 79.3%. Venous diameters in the pampiniform plexus were 3 mm or more in 61.5% of 130 subclinical left varicoceles. Of 30 patients with testicular microlithiasis, 14 had varicocele, 2 had epididymal cyst,s 3 had a history of mumps orchitis, 1 had retractile testis, and 1 had a history of orchiectomy for contralateral testicular tumor. CONCLUSIONS: The routine Color Doppler ultrasonography is valuable for diagnosing scrotal abnormalities in infertile men, frequently detecting non-palpable lesions. 相似文献
94.
SATORU KANTO HIDEO SAITO AKIHIRO ITO MAKOTO SATOH SEIICHI SAITO YOICHI ARAI 《International journal of urology》2004,11(10):890-893
AIM: Testicular tumors are not common pediatric solid tumors, especially in Asian children. There have been few reviews of cases in Japan to date. We present the clinical features of 14 pediatric testicular tumor patients. METHODS: Clinical features of 14 testicular tumor patients, such as chief complaints, age at diagnosis, pathology, stages, treatments and prognosis, were examined from medical records. Two patients had their semen tested at adolescence. RESULTS: Of the 14 prepubescent patients, 12 (85.7%) patients were diagnosed before 3 years of age. Ten cases (71.4%) were diagnosed as yolk sac tumors, three (21.4%) as mature teratomas and one case as an epidermoid cyst. Nine cases (90.0%) among the 10 cases of yolk sac tumor were diagnosed as stage I and one case was stage IV. One stage I yolk sac tumor patient developed lung metastasis later. Eventually, two yolk sac tumor patients died, despite chemotherapy. While all the cases with a diagnosis before 2 years of age survived, 67% (2/3) of cases with a diagnosis after the age of 2 died of tumors. Semen analysis in two patients showed normospermia. CONCLUSION: In the present study, the most common testicular tumors were yolk sac tumors and the patients diagnosed before 2 years of age showed favorable results. Age could be a relapse risk factor in yolk sac tumors. Guidelines for handling testicular tumors in children is not yet well established in Japan. An organized system seems necessary to gather and accumulate the results of the cases in Japan in order to develop better guidelines for treatment. 相似文献
95.
Metanephric Adenoma Treated with Laparoscopic Nephrectomy 总被引:2,自引:0,他引:2
TAKASHI EBINE REI OHARA TETSUO MOMMA SHIRO SAITO SHIGERU KURAMOCHI 《International journal of urology》2004,11(4):232-234
A 31-year-old-female presented with a left renal mass detected incidentally during an abdominal ultrasound examination. Computed tomography and angiography revealed a hypovascular solid tumor 4.5 cm in diameter at the middle portion of the left kidney. Laparoscopic left nephrectomy was performed and macroscopic examination of the specimen revealed encapsulated tumor with grayish yellow cut surface. Histological examination demonstrated that the tumor cells were small scant cytoplasms, containing round and regular nuclei, forming a glomerular-like structure. There was no mitosis nor cellular atypia indicating a malignant structure. The histological diagnosis was metanephric adenoma. 相似文献
96.
MOTOAKI SAITO MASAHITO KAWATANI YUKAKO KINOSHITA KEISUKE SATOH IKUO MIYAGAWA 《International journal of urology》2005,12(8):779-782
AIM: There is increasing evidence that non-steroidal anti-inflammatory drugs are effective for the treatment of nocturia. In this study, we attempted to investigate the role of loxoprofen sodium (loxoprofen) in the therapeutic management of patients with nocturia. METHODS: Fifteen benign protastatic hyperplasia and/or overactive bladder patients (13 males and 2 females, 71.1 +/- 1.5 years old) with three or more voids per night were involved. These patients had received standard drug therapy. Although these patients had received standard drug therapy for more than half a year, they had still three or more episodes of nocturia. The patients took a single dose of 60 mg of loxoprofen at night prior to sleep. Before and 1 week after the initiation of this therapy, the effects of this treatment were assessed by frequency volume chart and a questionnaire. RESULTS: In the questionnaire, seven patients answered as excellent, six patients demonstrated improvement of their symptoms, two patients did not show a significant change in their symptoms and no patients demonstrated a deterioration in the symptoms. In frequency volume chart, total void per day, total void per night, total urine volume per day, total night urine volume per day and single voided volume in the night before and after this treatment were 9.97 +/- 0.81 and 8.99 +/- 0.74 per day, 3.82 +/- 0.25 and 1.82 +/- 0.27 per night, 1349 +/- 81 and 1258 +/- 91 mL per day, 567 +/- 46 and 325 +/- 51 mL per night, and 143 +/- 13 and 149 +/- 10 mL, respectively. CONCLUSION: Loxoprofen can be effective and useful for patients with nocturia. Our data suggest that the main mechanism of this effect is to decrease urine production during a night's sleep. 相似文献
97.
Survival of childhood neoplasms has improved considerably during the past three decades. Improvement in survival rate for relatively infrequent neoplasms was assessed based on data obtained from the largest children's hospital in Japan. Using the data of the cancer registry of the hospital which recorded all the patients from 1965 to 1993 totalling 1026 cases, survival rate was analyzed for each type of neoplasm categorized by the S-classification for Childhood Neoplasms, a modification of the International Classification of Diseases. Survival was assessed for three 10 year periods from 1965 for infrequent neoplasms and for two 15 year periods for rare neoplasms. Improvement of survival was considerable in the neoplasms of the respiratory organs, genital organs and germ cell tumors, moderate in bone tumors and poor in the muscle and connective tissues. In conclusion, in some types of relatively infrequent neoplasms, survival improved considerably. But in soft parts and connective tissues (mostly rhabdomyosarcoma) improvement of survival was poor. 相似文献
98.
Shuji TERAI Isao SAKAIDA Mitsuru YASUNAGA Kiwamu OKITA Yasushi SHINGAI Mitsuru SAITO Harushige FURUTANI Kojiro SHIGETA Motoshige INOUE Motohiro TAKESHIGE 《Digestive endoscopy》1993,5(1):89-93
Abstract: In this study we report on two cases of amebic colitis treated in our hospital. On admission both patients were in a severe state of malnutrition due to intermittent diarrhea which had continued for one month. Both patients suffered from amebic colitis presumably transmitted by homosexual intercourse. A definite diagnosis of amebic colitis was made from both fecal examination and colonoscopic biopsy. After the diagnosis was made, the patients were treated with metronidazole. This medication can eliminate Entamoeba histolytica, although it was insufficient for the treatment of the patients’malnutrition. Therefore we used total parenteral nutrition to treat their malnutrition. It was successful and resulted in their recovery and discharge. These two cases indicate that total parenteral nutrition therapy is useful for supporting the recovery of patients with amebiasis. 相似文献
99.
100.