首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   9138篇
  免费   867篇
  国内免费   127篇
耳鼻咽喉   113篇
儿科学   254篇
妇产科学   451篇
基础医学   1103篇
口腔科学   207篇
临床医学   1052篇
内科学   2070篇
皮肤病学   124篇
神经病学   596篇
特种医学   242篇
外科学   1472篇
综合类   211篇
现状与发展   1篇
一般理论   1篇
预防医学   453篇
眼科学   161篇
药学   707篇
中国医学   85篇
肿瘤学   829篇
  2023年   64篇
  2022年   136篇
  2021年   293篇
  2020年   164篇
  2019年   320篇
  2018年   351篇
  2017年   266篇
  2016年   276篇
  2015年   337篇
  2014年   431篇
  2013年   496篇
  2012年   668篇
  2011年   718篇
  2010年   440篇
  2009年   396篇
  2008年   542篇
  2007年   545篇
  2006年   482篇
  2005年   479篇
  2004年   419篇
  2003年   366篇
  2002年   372篇
  2001年   240篇
  2000年   215篇
  1999年   173篇
  1998年   53篇
  1997年   61篇
  1996年   44篇
  1995年   39篇
  1994年   38篇
  1993年   21篇
  1992年   90篇
  1991年   77篇
  1990年   74篇
  1989年   64篇
  1988年   50篇
  1987年   28篇
  1986年   32篇
  1985年   41篇
  1984年   27篇
  1983年   22篇
  1982年   13篇
  1981年   22篇
  1979年   17篇
  1978年   10篇
  1977年   14篇
  1976年   12篇
  1975年   13篇
  1973年   13篇
  1972年   12篇
排序方式: 共有10000条查询结果,搜索用时 343 毫秒
141.
142.
143.
The above article from Journal of Advanced Nursing, published online on 26th June 2014 in Wiley Online Library ( wileyonlinelibrary.com ) has been retracted by agreement between the journal Editor‐in‐Chief and John Wiley & Sons Ltd. The retraction has been agreed due to considerable overlap with the following papers: Zhu L.‐X., Ho S.‐C., Sit J.W.H., He H.‐G. (2014) Effect of a transtheoretical model‐based stage‐matched exercise intervention on exercise behavior and angina in patients with coronary heart disease: a randomized controlled trial. Journal of Cardiovascular Nursing DOI: 10.1097/JCN.0000000000000162 . Zhu L.‐X., Ho S.‐C., Sit J.W.H., He H.‐G. (2014) The effects of a transtheoretical model‐based exercise stage‐matched intervention on exercise behavior in patients with coronary heart disease: A randomized controlled trial. Patient Education and Counseling 95, 384–392. Reference Zhu L‐X., Ho S‐C., Sit J.W.H. & He H‐G. (2014) Effects of a transtheoretical model–based exercise stage–matched intervention on exercise behaviour and quality of life in patients with coronary heart disease: a randomized controlled trial. Journal of Advanced Nursing. doi: 10.1111/jan.12469  相似文献   
144.
We retrospectively reviewed the results of cyclophosphamide (3 g/m2), doxorubicin and dexamethasone plus granulocyte‐colony stimulating factor (G‐CSF) (ID‐CY/DOX group), low‐dose cyclophosphamide (2 g/m2) plus G‐CSF (LD‐CY group) and G‐CSF alone (G‐CSF group) for stem cell mobilization in patients with multiple myeloma. A total of 89 patients with 93 mobilizations were included. Apheresis was started when total white blood cell (WBC) count >10 × 109/L for ID‐CY/DOX and LD‐CY groups and after eight doses of G‐CSF (5 μg/kg twice daily) for G‐CSF group. For five mobilizations in ID‐CY/DOX group, the rate of successful mobilization (≥4.0 × 106/kg CD34+ cells) was 80%. For 78 mobilizations in LD‐CY group, the successful rate was 80.8%. For 10 mobilizations in the G‐CSF group, the successful rate was 50%. The mean yield of CD34+ cells was higher in ID‐CY/DOX and LD‐CY groups as compared with that in G‐CSF group (P = 0.026 and 0.020, respectively). There was no difference in the yield of CD34+ cells between ID‐CY/DOX and LD‐CY groups (P = 0.831). After autologous stem cell transplantation, the days to neutrophil and platelet engraftment were similar in these three groups (P = 0.713 and 0.821, respectively). In conclusion, we observed that ID‐CY/DOX and LD‐CY plus G‐CSF for stem cell mobilization resulted in a higher successful rate and higher stem cell yields than G‐CSF alone and their engraftment time were similar. Total WBC count >10 × 109/L can be used as a guide to start apheresis in CY‐based stem cell mobilization. J. Clin. Apheresis 31:423–428, 2016. © 2015 Wiley Periodicals, Inc.  相似文献   
145.
146.

Aim

The aim of the present study was to determine the practice patterns in the management of anterior urethral strictures among urologists in Hong Kong.

Patients and Methods

A 14‐item questionnaire was delivered either directly or by mail to all 126 registered urologists in Hong Kong. Information including demographic data, number of anterior urethral strictures treated, diagnostic methods, treatment options and follow‐up strategy were collected. The questionnaire also asked for the personal opinion about the treatment plan of two stricture case scenarios.

Results

The response rate was 48 per cent. The majority (87 per cent) of urologists treated <10 anterior urethral strictures per year. Minimal invasive procedures, including urethral dilatation using metal sounds (77 per cent) or cystoscopy‐guided (74 per cent) and direct visual internal urethrotomy (57 per cent), were more commonly performed by urologists to treat urethral strictures. The majority of urologists (82.6 per cent) performed less than five urethroplasties per year. In the two case scenarios of long bulbous urethral stricture and recurrent short urethral stricture, approximately 10 per cent of respondents would refer the cases to other urologists and approximately 75 per cent would choose to perform reconstructive surgeries. The remaining 15 per cent of respondents would choose minimally‐invasive procedures for these strictures. Nearly two‐thirds (62.3 per cent) of urologists believed that urethroplasty should be proposed only after failed endoscopic treatment. Workups for urethral stricture disease were consistent, while the modalities to access the outcome were highly heterogeneous.

Conclusion

In Hong Kong, the majority of urologists choose to perform urethroplasty for long bulbous urethral strictures and recurrent short bulbous urethral strictures in a case scenario situation. However, in actual practice, most perform less than five urethroplasties per year. A small caseload, lack of experience and understanding of urethral reconstructive surgery means that most urologists in Hong Kong would hesitate to carry out primary urethroplasty in correctly‐selected patients for whom primary reconstruction would have been the treatment of choice.  相似文献   
147.
148.
Patients with X‐linked hyperimmunoglobulin M syndrome (XHIGM) have a defective CD40–CD40 ligand system and further immunoglobulin class‐switching. They may present with recurrent infection and malignancy involving the liver, pancreas or biliary tract. We report here a case of poorly differentiated transitional cell carcinoma in a young man with XHIGM even on regular treatment and discuss the possible pathogenesis. Given that the triggering of the CD40–CD40 ligand system has been found to improve tumor immunogenicity in recent studies, future immunotherapy targeting the CD40 ligand for these patients may be feasible to prolong their survival.  相似文献   
149.
A 14‐year‐old girl developed brownish round macules and patches over the face, trunk, and proximal limbs with extensive progression since she was 7 years old. Electron microscopy examination revealed an increase in the number and maturity of melanosomes in basal and suprabasal keratinocytes, although the number of melanocytes was within the normal range. A diagnosis of idiopathic eruptive macular pigmentation was made. We describe the unusual disease progression of this case of idiopathic eruptive macular pigmentation, which was thought to be self‐limited.  相似文献   
150.

Objective

Explore the perceived benefits of a Veterans Health Administration (VHA) geriatric specialty telemedicine service (GRECC Connect) among rural, older patients and caregivers to contribute to an assessment of its quality and value.

Data Sources

In Spring 2021, we interviewed a geographically diverse sample of rural, older patients and their caregivers who participated in GRECC Connect telemedicine visits.

Study Design

A cross-sectional qualitative study focused on patient and caregiver experiences with telemedicine, including perceived benefits and challenges.

Data Collection

We conducted 30 semi-structured qualitative interviews with rural, older (≥65) patients enrolled in the VHA and their caregivers via videoconference or phone. Interviews were recorded, transcribed, and analyzed using a rapid qualitative analysis approach.

Principal Findings

Participants described geriatric specialty telemedicine visits focused on cognitive assessments, tailored physical therapy, medication management, education on disease progression, support for managing multiple comorbidities, and suggestions to improve physical functioning. Participants reported that, in addition to prescribing medications and ordering tests, clinicians expedited referrals, coordinated care, and listened to and validated both patient and caregiver concerns. Perceived benefits included improved patient health; increased patient and caregiver understanding and confidence around symptom management; and greater feelings of empowerment, hopefulness, and support. Challenges included difficulty accessing some recommended programs and services, uncertainty related to instructions or follow-up, and not receiving as much information or treatment as desired. The content of visits was well aligned with the domains of the Age-Friendly Health Systems and Geriatric 5Ms frameworks (Medication, Mentation, Mobility, what Matters most, and Multi-complexity).

Conclusions

Alignment of patient and caregiver experiences with widely-used models of comprehensive geriatric care indicates that high-quality geriatric care can be provided through virtual modalities. Additional work is needed to develop strategies to address challenges and optimize and expand access to geriatric specialty telemedicine.  相似文献   
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号