全文获取类型
收费全文 | 436篇 |
免费 | 28篇 |
国内免费 | 6篇 |
专业分类
耳鼻咽喉 | 1篇 |
儿科学 | 5篇 |
基础医学 | 39篇 |
口腔科学 | 6篇 |
临床医学 | 26篇 |
内科学 | 65篇 |
皮肤病学 | 3篇 |
神经病学 | 4篇 |
特种医学 | 237篇 |
外科学 | 13篇 |
综合类 | 2篇 |
预防医学 | 6篇 |
眼科学 | 4篇 |
药学 | 44篇 |
肿瘤学 | 15篇 |
出版年
2023年 | 2篇 |
2021年 | 4篇 |
2020年 | 3篇 |
2019年 | 3篇 |
2018年 | 4篇 |
2016年 | 4篇 |
2015年 | 1篇 |
2014年 | 4篇 |
2013年 | 2篇 |
2012年 | 6篇 |
2011年 | 6篇 |
2010年 | 6篇 |
2009年 | 5篇 |
2008年 | 9篇 |
2007年 | 13篇 |
2006年 | 7篇 |
2005年 | 6篇 |
2004年 | 5篇 |
2003年 | 3篇 |
2002年 | 6篇 |
2001年 | 3篇 |
2000年 | 1篇 |
1999年 | 3篇 |
1998年 | 19篇 |
1997年 | 21篇 |
1996年 | 15篇 |
1995年 | 16篇 |
1994年 | 22篇 |
1993年 | 17篇 |
1992年 | 4篇 |
1991年 | 2篇 |
1990年 | 8篇 |
1989年 | 25篇 |
1988年 | 26篇 |
1987年 | 28篇 |
1986年 | 20篇 |
1985年 | 20篇 |
1984年 | 24篇 |
1983年 | 13篇 |
1982年 | 13篇 |
1981年 | 22篇 |
1980年 | 15篇 |
1979年 | 3篇 |
1978年 | 11篇 |
1977年 | 6篇 |
1976年 | 7篇 |
1975年 | 4篇 |
1974年 | 1篇 |
1972年 | 1篇 |
1969年 | 1篇 |
排序方式: 共有470条查询结果,搜索用时 31 毫秒
31.
Chest computed tomography (CT), including high-resolution CT with thin (1.5-mm) sections was used to evaluate proved (pathologically or clinically) lymphangitic spread (LS) of tumor in 12 patients. These appearances were compared with thin-section scans obtained in 11 healthy subjects. Thin-section CT demonstrated findings consistent with thickening of the normal lung interstitium. In all patients, thin sections showed an increase in the number of peripheral lines (1-2 cm in length) that were diffuse in generalized disease and localized in focal disease. Normal peripheral arcades were not increased in number, but the limbs forming the arcades were thickened in all patients. A diffuse increase in linear and curvilinear structures (reticular pattern) was seen toward the center of the lung. Polygonal structures 1-2 cm in diameter were seen in seven patients with LS but not in healthy subjects. Fissures were thickened in nine patients. Selected 1.5-mm-thick CT sections are recommended through abnormal areas (seen at CT or on chest radiographs) or if these are normal at three levels (midapex, hilus, and 3 cm above the diaphragm) when scanning patients with tumors known to cause LS. 相似文献
32.
Mercado S; Hunter DW; Castaneda-Zuniga WR; Amplatz K; Young AT; Cardella JF; Lange PH; Hulbert JC; Reddy P 《Radiology》1986,158(1):207-209
Percutaneous nephrostolithotomy, which can require a double puncture, is presently the method of choice in our institution for the removal of renal stones. Patients that underwent this procedure were evaluated to identify the possible reasons for the double puncture. Of 200 patients evaluated, 14 needed a second tract. The three variables that determined whether a second puncture was needed, in order of importance, were number and size of the stones, with second tracts needed in patients with multiple stones and staghorn calculi; anatomical variations of the renal collecting system itself, with bifid systems the most significant anatomic variation; and the dexterity of the radiologist in performing the puncture and the ability of the urologist to extract the stone. Second tracts were needed more frequently in patients who presented with stones in both the lower and middle poles of the collecting systems. 相似文献
33.
Darcy MD; Cardella JF; Hunter DW; Smith TP; Castaneda-Zuniga WR; Lund G; Amplatz K 《Radiology》1986,161(3):611-614
The Amplatz retrievable vena caval filter was designed in an attempt to decrease complications associated with the placement of Mobin-Uddin or Kimray-Greenfield filters. The design allows percutaneous retrieval, thus expanding application of the filter to situations requiring temporary prophylaxis against pulmonary embolism. Filters have been placed in 16 patients, nine (56%) for prophylactic purposes. All filters were easily inserted percutaneously. Complications occurred in three patients; these included complete thrombosis of the inferior vena cava below the filter, misplacement of one filter into the pericaval retroperitoneal tissue, and development of thrombus cranial to the filter. With the current introduction system, the possibility of filter misplacement has been essentially eliminated. No patient experienced symptoms suggestive of pulmonary embolism after filter insertion. One filter retrieval has been performed, with no complications. 相似文献
34.
35.
36.
37.
The influence of pulsed low-intensity ultrasound on matrix production of chondrocytes at different stages of differentiation: an explant study 总被引:4,自引:0,他引:4
Zhang Zi Huckle J Francomano CA Spencer RG 《Ultrasound in medicine & biology》2002,28(11-12):1547-1553
The proximal and distal parts of sterna of chick embryos represent cartilage undergoing endochondral ossification and hyaline cartilage, respectively. Cartilage explants from both regions were exposed for 20 min to pulsed low-intensity ultrasound (PLIUS) with an intensity of 30 mW. cm(-2) (spatial average-temporal average) at a frequency of 1.5 MHz, with a pulse burst frequency of 1 kHz and burst duration of 200 micros. Histological and immunohistochemical analysis was performed on days 1, 3, 5 and 7 after treatment. An anabolic effect of PLIUS on matrix production was shown by an increase of up to 10% to 20% in quantitative immunohistochemical staining for type II collagen and aggrecan in the two parts of the sternum. PLIUS also increased type X collagen staining by up to 10% in certain regions of the proximal part of the sternum. Staining for type X collagen was negative in the distal part of the sternum in both PLIUS and control groups. These results suggest that PLIUS may stimulate bone formation by increasing hypertrophy of chondrocytes directed to terminal differentiation. However, PLIUS did not induce hypertrophy in hyaline cartilage; moreover, increased matrix synthesis indicates a potential role in cartilage repair. 相似文献
38.
蛋白质组学及其相关技术在运动人体科学中的应用 总被引:1,自引:0,他引:1
目的:对蛋白组学及蛋白芯片技术发展现状进行综述,为该技术在运动医学中的应用提供参考资料。资料来源:应用计算机检索PubMed2003-01/2006-12期间相关蛋白组学及蛋白芯片技术方面的文章,检索词“exercise AND protein chip,protein microarray”,并限定文章语言种类为English。同时计算机检索万方数据库2003-01/2006-12期间相关蛋白组学及蛋白芯片技术方面的文章,检索词“蛋白质,运动锻炼,运动医学”,并限定文章语言种类为中文。资料选择:对资料进行初审,并查看每篇文献后的引文。纳入标准:文章所述内容应与蛋白质组学及蛋白质芯片技术的研究相关。排除标准:重复研究或Meta分析类文章。资料提炼:共收集到312篇相关文献,32篇文献符合纳入标准,排除的280篇文献为内容陈旧或重复。资料综合:蛋白组学研究已成为基因组学研究后生命科学发展的大方向之一。它研究的主要内容包括:蛋白质分离与鉴定、蛋白质功能的确定、蛋白质翻译后修饰及相互作用、各种疾病或疲劳标志物的筛选与疾病诊断、生物信息学及药物开发等方面。文章在对蛋白质组学的发展及其相关技术在运动人体科学中的应用现状进行综述的基础上,对运动人体科学未来的发展方向进行了展望。由于蛋白质组学的建立以及蛋白质芯片技术的逐步完善,对运动人体科学的研究及其发展将起到很好的促进作用。结论:未来将从分子水平上阐明运动与人体适应的分子生物学机制,研究热点将集中于从运动营养蛋白质组学、反兴奋剂的蛋白质芯片技术、运动员机能评定的蛋白质芯片研究等方面。 相似文献
39.
Oral sumatriptan in the acute treatment of migraine and migraine recurrence in general practice 总被引:1,自引:0,他引:1
Scott RJ; Aitchison WR; Barker PR; McLaren GI 《QJM : monthly journal of the Association of Physicians》1996,89(8):613-622
We investigated the efficacy, safety and tolerability compared with placebo
of a second dose of oral sumatriptan 100 mg in 1349 general practice
patients who had already treated a moderate or severe migraine headache
with 100 mg sumatriptan 4 h earlier. Headache was relieved by the first
sumatriptan dose in about 70% of patients, but the second dose did not
produce significantly more relief than placebo, either in nonresponders or
in the group as a whole, nor did it reduce other symptoms (photophobia,
nausea, vomiting, etc,) at 8 h, or influence the incidence of headache
recurrence. The drug was well-tolerated, and a further single dose was
effective in treating recurrence after initial relief. A single 100 mg dose
of sumatriptan is an effective acute treatment for migraine. A second dose
should be reserved for treating headache recurrence.
相似文献