滨海沙土微量元素与木麻黄生长的关系

本文探讨了广东滨海沙土中微量元素B、Mo、Mn、Cu、Zn与木麻黄生长的关系,结果表明:B、Mo有利于促进生长与抗病,Cu含量高对生长有抑制作用,其余的作用不明显。     

唇腭裂的牙槽突裂植骨修复术

牙槽突植骨术是唇腭裂序列治疗的一个组成部分,对于恢复上颌牙弓的完整性,保证上颌牙齿的正常萌出,促进上颌骨的垂直向生长及颌骨的稳定性,矫正患侧鼻底塌陷畸形及修复唇侧口鼻腔瘘均有重大意义。总结了保证手术成功的关键,并认为植骨术前后应接受正畸治疗。8～11岁 X 线片示尖牙根形成2/3为最佳手术时间。     

高频消融心室肌和心律失常的实验研究

应用2.59MHz的高频消融心室肌和兔实验性心律失常的兴奋灶。结果表明,高频可引起心肌局灶性凝固性坏死;高频消融乌头碱注射部位,可使实验性心律失常恢复正常的时间明显缩短。高频消融未见有并发症。     

高血糖对非胰岛素依赖型糖尿病患者红细胞（Ca~（2＋）－Mg~（2＋））－ATP酶的影响

为了解高血糖对非胰岛素依赖型糖尿病（ＮＩＤＤＭ）患者红细胞膜（Ｃａ２＋－Ｍｇ２＋）－Ａｒｐ酶的影响，采用改良的Ｈａｎａｈａｎ和Ｌｕｔｈｒａ法测定了红细胞膜（Ｃａ２＋－Ｍｇ２＋）－ＡＴＰ酶活性。结果表明，ＮＩＤＤＭ患者红细胞膜（Ｃａ２＋－Ｍｇ２＋）－ＡＴＰ酶活性降低，且与空腹血糖、糖化血红蛋白、果糖胺及红细胞变形指数呈负相关，后者与红细胞内Ｃａ２＋浓度呈正相关。说明（Ｃａ２＋－Ｍｇ２＋）－ＡＴＰ酶活性下降时，红细胞变形能力降低，可能与患者红细胞膜蛋白的过度糖化及细胞内Ｃａ２＋浓度的增高有关。     

A STUDY ON DETECTION OF SERUM FASTING TOTAL BILE ACID AND CHOLOYGLYCIN IN NEONATE FOR CHOLESTASIS

ＡＳＴＵＤＹＯＮＤＥＴＥＣＴＩＯＮＯＦＳＥＲＵＭＦＡＳＴＩＮＧＴＯＴＡＬＢＩＬＥＡＣＩＤＡＮＤＣＨＯＬＯＹＧＬＹＣＩＮＩＮＮＥＯＮＡＴＥＦＯＲＣＨＯＬＥＳＴＡＳＩＳＧｕｏＷｅｎ（郭文）；ＷｕＭｉｎｇｃｈａｎｇ（吴明昌）；ＰｅｉＸｕｅｙｉ（裴学义）；Ｇ...     

薄层扫描法测定食物中胆固醇的含量

本文探讨食物中胆固醇的薄层光密度法的测定。用硅胶Ｇ与０．３％ＣＭＣ－Ｎａ按１：２．２比例制成薄层板，石油醚－乙醚－－冰醋酸（７：３：０．１）为展开剂，５％磷钼酸乙醇溶液显色，日本岛津ＣＳ－９１０型薄层扫描仪定量扫描，测得精神异系数（ＲＤＳ％）为２．９２。稳定性变异系数（ＲＳＤ％）为２．３５，加嘏率在８７．９５－９４．２９％范围内。与气相色谱法（其回收率在９２－１０３％范围）比较，结果相接近，该法简     

日本血吸虫病患者幽门螺杆菌感染分析

目的：探讨日本血吸虫病患者中Hp的感染状况。方法：利用Hp全菌抗原ELISA定量检测不同类型日本血吸虫病患者血清抗HpIgG。结果：日本血吸虫病患者组血清抗HpIgG检出率（75％）明显高于对照组（46％），平均抗体水平（2.30±0.42）亦高于对照组（2.02±0.38），抗HpIgG的检出率和平均抗体水平随病程的发展而升高，血清抗HpIgG水平与血清抗AWA抗体水平高度相关（r＝0.92）。结论：日本血吸虫病患者的Hp感染率明显高于其他人，早期诊断并及时治疗Hp感染，对于控制晚期血吸虫病病变的发展和改善其预后具有重要意义。     

The effect of intrauterine devices (stainless steel ring, copper-T220 and levonorgestrel) on the DNA content in isolated human endometrial cells

The effect of three different intrauterine devices on the DNA content in human endometrial cells has been studied in 29 women before and after the insertion of an IUD; a stainless steel ring (9 subjects), Copper-T220 (11 subjects) and a medicated IUD releasing levonorgestrel at a rate of 2 micrograms/day (9 subjects). The material was grouped into "bleeders" (having more than 8 days of bleeding and spotting per month) and "non-bleeders" (having less than 8 days of bleeding and spotting per month). The DNA content was assessed on isolated endometrial cells smeared from thin biopsies and the amount of DNA per cell nucleus was measured by means of a Feulgen microspectrophotometric method. No significant difference was found between the "bleeders" and the "non-bleeders" as to the DNA content. Nevertheless, when the total number of subjects were pooled together, a significant increase in the DNA content was found in the post-insertion specimens in the groups of women using the SS and the T-Cu IUDs. Furthermore, a significant decrease in the DNA content was also found when the specimens obtained after the insertion of the LNG IUD were compared with those obtained after 24 months' use of the stainless steel ring and the Copper-T220 device (p less than 0.01 and p less than 0.002, respectively). It is concluded that the insertion of an inert IUD or an T-Cu IUD, induces significant alterations in the DNA content of the human endometrium adjacent to the device, whereas the use of the LNG device does not significantly modify the DNA synthesis when used for 3-10 months. No correlation was found between the DNA content per cell and the number of days of bleeding and spotting.     

五味与毒性关系的探讨

毒性的产生应有物质基础,这种物质基础就是五味,中药的功效和毒性均来自五味。在五味中有毒药物的数量以辛、苦味为多,甘味最少,酸、咸味居中。     

Attachment and spreading of fibroblasts on an RGD peptide-modified injectable hyaluronan hydrogel

Hyaluronan (HA) hydrogels resist attachment and spreading of fibroblasts and most other mammalian cell types. A thiol-modified HA (3,3'-dithiobis(propanoic dihydrazide) [HA-DTPH]) was modified with peptides containing the Arg-Gly-Asp (RGD) sequence and then crosslinked with polyethylene glycol (PEG) diacrylate (PEGDA) to create a biomaterial that supported cell attachment, spreading, and proliferation. The hydrogels were evaluated in vitro and in vivo in three assay systems. First, the behavior of human and murine fibroblasts on the surface of the hydrogels was evaluated. The concentration and structure of the RGD peptides and the length of the PEG spacer influenced cell attachment and spreading. Second, murine fibroblasts were seeded into HA-DTPH solutions and encapsulated via in situ crosslinking with or without bound RGD peptides. Cells remained viable and proliferated within the hydrogel for 15 days in vitro. Although the RGD peptides significantly enhanced cell proliferation on the hydrogel surface, the cell proliferation inside the hydrogel in vitro was increased only modestly. Third, HA-DTPH/PEGDA/peptide hydrogels were evaluated as injectable tissue engineering materials in vivo. A suspension of murine fibroblasts in HA-DTPH was crosslinked using PEGDA plus PEGDA peptide, and the viscous, gelling mixture was injected subcutaneously into the flanks of nude mice; gels formed in vivo following injection. After 4 weeks, growth of new fibrous tissue had been accelerated by the sense RGD peptides. Thus, attachment, spreading, and proliferation of cells is dramatically enhanced on RGD-modified surfaces but only modestly accelerated in vivo tissue formation.