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排序方式: 共有2333条查询结果,搜索用时 15 毫秒
31.
32.
Yoshinobu Nagasawa Tomoharu Shimizu Hiromichi Sonoda Hirotomi Chou Eiji Mekata Tohru Tani 《Surgery today》2014,44(7):1346-1349
Catheter rupture after totally implantable access port (TIAP) implantation via the right internal jugular vein is thought to be very rare. We report a case of catheter rupture found 682 days after TIAP surgery in a 52-year-old woman with recurrent right breast cancer. It is possible that chronic stress at the flexure of the catheter induced by neck movements caused the catheter to rupture. Therefore, when inserting a TIAP via the right internal jugular vein, the site of venous puncture should be decided on carefully. Although a fracture of this type is rarely reported in the literature, the incidence of catheter injury of a TIAP inserted via the internal jugular vein at our institute is 1.8 %. This highlights the need to educate and caution medical staff and patients about preventing catheter fracture being caused by external factors. 相似文献
33.
Diagnostic efficacy of liquid‐based cytology for solid pancreatic lesion samples obtained with endoscopic ultrasound‐guided fine‐needle aspiration: Propensity score‐matched analysis 下载免费PDF全文
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35.
Akinori Mitsui Midori Yoshizawa Hiromichi Matsumoto Emiko Fukui 《Journal of assisted reproduction and genetics》2009,26(1):35-39
Purpose The effects of reciprocal transplantation of meiosis-II chromosomes between senescent and young mouse oocytes were evaluated
based on pre- and post-implantation development ability of resultant embryos.
Methods Karyoplasts including meiosis-II chromosomes of oocytes from senescent Rockefeller mouse/Ms-Rb(6, 15) females (10 to 12 months,
age-related infertile mice) were transferred into cytoplasts of oocytes from young F1 females (3 to 5 months). Reconstructed oocytes were fertilized in vitro, and then the resultant embryos were cultured in
vitro and transferred to recipient mice.
Results The reconstructed oocytes that consisted of aged-karyoplasts and young-cytoplasts showed significantly improved embryonic
development (from 23.2% to 30.0%) and development to term (from 6.3% to 27.1%, P < 0.05) as compared with the oocytes reconstructed from young-karyoplasts and aged-cytoplasts.
Conclusions The present study showed successful rejuvenation for age-related infertility using transplantation of meiosis-II chromosomes
in animal experimental models.
Capsule Transplantation of meiosis-II chromosomes of senescent mouse oocytes into cytoplasts of young mouse oocytes improves subsequent
embryonic and fetal development until birth. 相似文献
36.
Takashi Tsukahara Masaru Tamura Hiromichi Yamazaki Hideyuki Kurihara Shigeru Matsuzaki 《Journal of cancer research and clinical oncology》1992,118(3):171-175
Summary The effects of -difluoromethylornithine (DFMO), radiation and the therapy of their combination were investigated in rats bearing G-XII glioma. DFMO treatment as well as radiation therapy prolonged the survival period when compared to the results in non-treated control rats. The combination therapy showed a greater effect on the survival rate than the single therapies, the effect being additive. The concentration of putrescine, spermidine, andN
1-acetylspermidine in tumor tissues was lowered by DFMO, while that of spermine was slightly elevated. Radiation decreased the concentration of all the polyamines, putrescine, spermidine, spermine andN
1-acetylspermidine. The concomitant treatment with DFMO and radiation further decreased the concentrations of putrescine andN
1-acetylspermidine in tumor tissues. The survival period of glioma-bearing rats is inversely correlated with the tissue levels of putrescine plusN
1-acetylspermidine.Abbreviations DFMO
-difluoromethylornithine
- BrdUrd
bromodeoxyuridine 相似文献
37.
Differences in the clinical course of acute massive and submassive pulmonary embolism. 总被引:1,自引:0,他引:1
Takeshi Yamamoto Naoki Sato Hiroyuki Tajima Hiromichi Takagi Norishige Morita Koichi Akutsu Nobuhiko Fujita Masahiro Yasutake Keiji Tanaka Teruo Takano 《Circulation journal》2004,68(11):988-992
BACKGROUND: Acute massive or submassive pulmonary embolism (PE) has high mortality, but the clinical course according to the location of onset (ie, in-hospital or out-of-hospital) is unknown. METHODS AND RESULTS: In the present study 56 consecutive patients with acute massive or submassive PE were studied retrospectively and a comparison made of the clinical characteristics, and outcomes between in-hospital onset (Group A) and out-of-hospital onset (Group B). Patients in Group A (n=28) had more frequent comorbidities with hemodynamic instability (54% vs 4%, p<0.0001) and temporary risk factors (93% vs 11%, p<0.0001), whereas patients in Group B (n=28) had a longer duration of symptoms (median: 5.5 days vs 0.5 day; p<0.0001), and had higher systolic pulmonary artery pressure (63+/-17 mmHg vs 46+/-12 mmHg, p=0.0006). Although in-hospital mortality did not differ between the 2 groups, the recurrence rate was higher in Group B (23% vs 0%, p=0.03). CONCLUSIONS: Patients who had in-hospital onset of PE had mostly temporary risk factors, unstable hemodynamics and a lower recurrence rate compared with the cases of out-of-hospital onset. In cases of in-hospital onset, prompt diagnosis and suitable treatment is needed to prevent fatalities and cases of out-of-hospital onset should be followed carefully for recurrence. 相似文献
38.
Li X Tjwa M Van Hove I Enholm B Neven E Paavonen K Jeltsch M Juan TD Sievers RE Chorianopoulos E Wada H Vanwildemeersch M Noel A Foidart JM Springer ML von Degenfeld G Dewerchin M Blau HM Alitalo K Eriksson U Carmeliet P Moons L 《Arteriosclerosis, thrombosis, and vascular biology》2008,28(9):1614-1620
39.
Yuki Igarashi Sho Tashiro Yuki Enoki Kazuaki Taguchi Kazuaki Matsumoto Hiroki Ohge Hiromichi Suzuki Atsushi Nakamura Nobuaki Mori Yoshitomo Morinaga Yuka Yamagishi Sadako Yoshizawa Katsunori Yanagihara Hiroshige Mikamo Hiroyuki Kunishima 《Journal of infection and chemotherapy》2018,24(11):907-914
At present, vancomycin (VCM) and metronidazole (MNZ) are used for the first-line standard treatment of Clostridioides difficile infection (CDI). However, their differential use has not been sufficiently investigated. In this study, a meta-analysis on differences in the efficacy for CDI between VCM and MNZ was performed. Reports of randomized controlled studies using VCM or MNZ to treat CDI were surveyed. Meta-analysis was performed using the Mantel-Haenszel method and random-effects model, and the risk ratio and 95% confidence interval were calculated. Excluding overlapping reports, 1043 reports were extracted and 5 randomized controlled studies were extracted. There was no difference in therapeutic effects for CDI between VCM and MNZ (RR = 1.08, 95% CI (0.99–1.17), p = 0.09, I2 = 37%). On subgroup analysis by the severity, there was no difference in the clinical effects for CDI between VCM and MNZ in non-severe cases (risk ratio: 1.09, 95% confidence interval: 1.00–1.19, p = 0.06), but the clinical effects of VCM were significantly higher than those of MNZ in severe cases (risk ratio: 1.19, 95% confidence interval: 1.02–1.39, p = 0.03). No significant difference was noted in the recurrence rate, incidence of adverse event, time to exhibit therapeutic effects, or judgment of the bacteriological effects. As the therapeutic effects of VCM were superior in severe CDI cases, VCM should be considered first in severe cases. 相似文献
40.
Kiyoko Tamai Yusaku Akashi Yuta Yoshimoto Yuji Yaguchi Yosuke Takeuchi Masanari Shiigai Jun Igarashi Yumi Hirose Hiromichi Suzuki Kiyofumi Ohkusu 《Journal of infection and chemotherapy》2018,24(12):998-1003
An 83-year-old previously self-sufficient man was referred to our hospital for a fever, severe tenderness over the lumbar spine, and elevated C-reactive protein levels. Computed tomography revealed fluid collection in the intervertebral space of L3/4. Gram-positive, short rod-shaped bacteria were isolated from two sets of blood cultures. A 16S rRNA sequence analysis of an isolate showed a similarity of 98.1% to the nearest type strain Brachybacterium squillarum JCM 16464T. Biochemical characteristics of the presently isolated strain differed from those of the most closely related species of the genus Brachybacterium. The patient was successfully discharged on day 73 of admission with antimicrobial therapies and showed no recurrence during outpatient visits. Brachybacterium spp. have mainly been isolated from the environment, and human Brachybacterium infections have rarely been documented to date. To our knowledge, this is the first clinical isolation of Brachybacterium sp. as a causative pathogen of bloodstream infection. 相似文献