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991.
992.
Cooke GS Segal S Hill AV;Tuberculosis Genetics Environment 《The New England journal of medicine》2002,347(24):1978-80; author reply 1978-80
993.
Improving the image of nursing and finding ways to encourage young people to enter the nursing field are two areas that need attention from nurse executives. That concept was turned into reality with Inova Nursing Exploration Summer Camp 2001, a camp for seventh and eighth graders who are exploring their interest in nursing careers. The camp was a unique partnership among a county public school system, a local university, and an integrated healthcare system. The program, developed by the system nurses in consultation with middle school educators, introduced students to the nursing profession via demonstrations, site visits at multiple hospitals, role-playing, discussions, and a trip to the local nursing school to experience life as a nursing student. The authors discuss the planning, implementation, and outcome of this unique summer camp. 相似文献
994.
Hill TV 《Respiratory care》2002,47(5):571-577
INTRODUCTION: Respiratory therapists evaluate the condition of their patients, make decisions about the appropriateness of the treatment plan, provide care, and evaluate the outcomes of their decisions. To practice effectively they must think critically and make appropriate decisions. As educators make curriculum changes to improve students' decision-making (DM) skills, strategies to develop critical thinking (CT) have been proposed as one method of achieving that goal. This approach is based on the hypothesis that a positive relationship exists between DM and CT. The present study examines the relationship between CT and DM in respiratory care students. If there is a positive relationship between CT and DM, respiratory care training programs might improve the DM skills of future practitioners by providing instruction that improves CT. METHODS: Using a correlational research design, DM scores from the Clinical Simulation Self-Assessment Examination (CSSAE) were compared with scores from the Watson-Glaser Critical Thinking Appraisal for 143 graduating respiratory care students from 10 programs. Program directors completed a questionnaire and were then interviewed about the methods they employ to develop CT and DM in their students. RESULTS: A significant correlation between CT and DM was found for 110 students completing the Secure Form of the CSSAE (r = 0.32, p < 0.01). All programs used case studies and clinical simulations, and most used role modeling, computer-assisted instruction, patient rounds, small group discussion, and study skills courses. No differences were identified in the use of the CT and DM development strategies by different programs. CONCLUSIONS: The findings support the belief that students with strong CT proficiency make better clinical decisions. Assessment of CT proficiency could be used as one part of a process for evaluating prospective students and faculty for respiratory care programs. Program directors and faculty felt that case studies and clinical simulations are important strategies. 相似文献
995.
Furness PN Taub N Assmann KJ Banfi G Cosyns JP Dorman AM Hill CM Kapper SK Waldherr R Laurinavicius A Marcussen N Martins AP Nogueira M Regele H Seron D Carrera M Sund S Taskinen EI Paavonen T Tihomirova T Rosenthal R 《The American journal of surgical pathology》2003,27(6):805-810
Histologic grading systems are used to guide diagnosis, therapy, and audit on an international basis. The reproducibility of grading systems is usually tested within small groups of pathologists who have previously worked or trained together. This may underestimate the international variation of scoring systems. We therefore evaluated the reproducibility of an established system, the Banff classification of renal allograft pathology, throughout Europe. We also sought to improve reproducibility by providing individual feedback after each of 14 small groups of cases. Kappa values for all features studied were lower than any previously published, confirming that international variation is greater than interobserver variation as previously assessed. A prolonged attempt to improve reproducibility, using numeric or graphical feedback, failed to produce any detectable improvement. We then asked participants to grade selected photographs, to eliminate variation induced by pathologists viewing different areas of the slide. This produced improved kappa values only for some features. Improvement was influenced by the nature of the grade definitions. Definitions based on "area affected" by a process were not improved. The results indicate the danger of basing decisions on grading systems that may be applied very differently in different institutions. 相似文献
996.
Hyperperfusion syndrome: toward a stricter definition 总被引:13,自引:0,他引:13
OBJECTIVE: Hyperperfusion syndrome is a rare and potentially devastating complication of carotid endarterectomy or carotid artery angioplasty and stenting. With the advent of new imaging techniques, we reviewed our experience with this phenomenon. METHODS: This report is a retrospective review of 129 consecutive cases of carotid endarterectomy performed between June 1, 2000, and May 31, 2002, and 44 consecutive cases of carotid artery angioplasty and stenting performed between January 1, 1997, and May 31, 2002. We specifically searched for examples of patients who developed postprocedural nonthrombotic neurological deficits that typified the hyperperfusion syndrome. RESULTS: Seven cases of hyperperfusion syndrome occurred, four after endarterectomy (3.1% of carotid endarterectomy cases) and three after stenting (6.8% of stenting cases). The cases of hyperperfusion were classified as presenting with 1). acute focal edema (two cases with stroke-like presentation, attributable to edema immediately after revascularization), 2). acute hemorrhage (two cases of intracerebral hemorrhage immediately after stenting and one case immediately after endarterectomy), or 3). delayed classic presentation (two cases with seizures, focal motor weakness, and/or late intracerebral hemorrhage at least 24 hours after endarterectomy). CONCLUSION: Hyperperfusion syndrome may be more common and more variable in clinical presentation than previously appreciated. 相似文献
997.
INTRODUCTION: Several mathematical models describe the relationship between velocity and time to fatigue. PURPOSE: The purposes of this study were to evaluate different critical velocity (V(critical)) models applied to rowing ergometry and to investigate prediction of performance time in a 2000-m race based on results from shorter trials. METHODS: Sixteen men performed seven rowing ergometer tests. Velocity and time to fatigue data from the 200-m (approximately 0.5 min) to 1200-m (approximately 3 min) trials and from the 200-m to 2000-m (approximately 6.5 min) trials were fit to a two-parameter hyperbolic model, a three-parameter hyperbolic model, and a three-parameter exponential model. RESULTS: Including data from the 2000-m trial generally resulted in higher R2 and smaller SEE. V(critical) from the three versions of the two-parameter model were 4.71 +/- 0.28 m x s(-1), 4.80 +/- 0.27 m x s(-1), and 5.04 +/- 0.24 m x s(-1) (P < 0.001). The two three-parameter models had high R2 (0.991 and 0.990, respectively) and generated parameter estimates that appeared reasonable. Time for a 2000-m race was predicted better using the two-parameter model (r > 0.974) than using the three-parameter models (r = 0.820-0.870). CONCLUSION: It is necessary to include the relatively long 2000-m predicting trial to describe accurately the velocity-time relationship in rowing. The two-parameter model may be useful in predicting time for a 2000-m race but is not otherwise appropriate for modeling when predicting trials of <1 min duration are included. Choice of model and duration of trials must be considered when using mathematical modeling to derive V(critical) and other parameters in rowing. 相似文献
998.
Heart xenograft survival with chimeric pig donors and modest immune suppression 总被引:6,自引:0,他引:6 下载免费PDF全文
Beschorner WE Sudan DL Radio SJ Yang T Franco KL Hill AC Shearon CC Thompson SC Dixon RS Johnson ND Kuszynski CA Rubocki RJ Lechtenberg KF Matamoros A Goertzen TC Fox IJ Langnas AN 《Annals of surgery》2003,237(2):265-272
OBJECTIVE: To assess the use of donor pigs with cellular chimerism for prevention of acute rejection with modest immune suppression. The clinical use of pig organ xenografts is currently precluded by severe acute rejection, which resists standard immune suppression. SUMMARY BACKGROUND DATA: For long-term survival of pig organ xenografts, immune suppression significantly greater than used with allografts would currently be necessary, leaving the recipient immune deficient and at increased risk for infections. Induction of immune tolerance and tissue accommodation could enhance xenograft survival but would lead to complications and frequent graft failure. Induction of cellular chimerism within the donor pigs, however, could accomplish these goals before transplantation, significantly reducing the risk. METHODS: Marrow cells from sheep were infused into fetal pigs. Heart xenografts from chimeric or nonchimeric pigs were transplanted heterotopically into recipient sheep, simultaneous with infusion of splenocytes. Posttransplant suppression consisted of cyclosporine and tapered corticosteroids, comparable with allotransplants. RESULTS: All of the control grafts (n = 12) were rejected by acute vascular rejection in 4 to 8 days. In contrast, only one episode of vascular rejection was observed in the experimental group (n = 13). Four experimental recipients had an episode of moderate diffuse cellular rejection (grade 3) and one had moderate focal cellular rejection (grade 2). Each episode responded to pulse steroids. Seven grafts showed no significant rejection. There was little evidence of immune deficiency, infection, or toxicity. CONCLUSIONS: Acute vascular rejection was prevented in a large animal model without the need for severe immune suppression. 相似文献
999.
Kocvara R Dolezal J Hampl R Povýsil C Dvorácek J Hill M Díte Z Stanek Z Novák K 《European urology》2003,43(4):430-435
OBJECTIVES: To study the andrological outcome of the division of testicular lymphatic vessels at varicocelectomy in children and adolescents. METHODS: Testicular size and basal and stimulated luteinizing hormone (LH) and follicle-stimulating hormone (FSH) values were determined prospectively in 86 patients with left unilateral varicocele grades II-III. 22 patients underwent lymphatic non-sparing surgery (LNS group), 10 of them with artery sparing (LNS/AS) and 12 without artery sparing (LNS/ANS), 23 patients underwent lymphatic sparing repair (LS group) and 41 patients were treated conservatively (NT group). RESULTS: The LNS group demonstrated significantly greater left testicular enlargement at six weeks and one year following repair, left testicular hypertrophy developed in 31.8% and hydrocele in 22.7% of patients. Marked oedema of intertubular tissue and a varying degree of tubular injury was observed in boys surgically treated for hydrocele. In the LS group, neither hypertrophy nor hydrocele developed postoperatively, the LH stimulated values were lower than in LNS/ANS group (p<0.05) and the NT group (p<0.04), the FSH stimulated values were lower than in the LNS/ANS group (p<0.001). CONCLUSIONS: Division of lymphatic vessels at varicocelectomy is associated with an excessive increase in testicular volume due to oedema, and with a reduced testicular function according to higher LH and FSH stimulated values. Preservation of lymphatics is strongly advised in varicocelectomy in adolescents to ensure better andrological outcome. 相似文献
1000.