全文获取类型
收费全文 | 454篇 |
免费 | 15篇 |
国内免费 | 15篇 |
专业分类
儿科学 | 43篇 |
妇产科学 | 3篇 |
基础医学 | 33篇 |
口腔科学 | 6篇 |
临床医学 | 41篇 |
内科学 | 118篇 |
皮肤病学 | 4篇 |
神经病学 | 5篇 |
特种医学 | 128篇 |
外科学 | 24篇 |
综合类 | 44篇 |
预防医学 | 9篇 |
药学 | 11篇 |
肿瘤学 | 15篇 |
出版年
2021年 | 3篇 |
2020年 | 1篇 |
2019年 | 2篇 |
2018年 | 5篇 |
2017年 | 2篇 |
2016年 | 1篇 |
2015年 | 3篇 |
2014年 | 5篇 |
2013年 | 10篇 |
2012年 | 4篇 |
2011年 | 5篇 |
2010年 | 7篇 |
2009年 | 14篇 |
2008年 | 2篇 |
2007年 | 9篇 |
2006年 | 9篇 |
2005年 | 10篇 |
2004年 | 4篇 |
2003年 | 7篇 |
2002年 | 3篇 |
2001年 | 2篇 |
2000年 | 6篇 |
1999年 | 9篇 |
1998年 | 23篇 |
1997年 | 39篇 |
1996年 | 45篇 |
1995年 | 23篇 |
1994年 | 25篇 |
1993年 | 25篇 |
1992年 | 7篇 |
1991年 | 4篇 |
1990年 | 8篇 |
1989年 | 17篇 |
1988年 | 20篇 |
1987年 | 16篇 |
1986年 | 22篇 |
1985年 | 8篇 |
1984年 | 8篇 |
1983年 | 7篇 |
1982年 | 13篇 |
1981年 | 7篇 |
1980年 | 10篇 |
1979年 | 2篇 |
1978年 | 8篇 |
1977年 | 6篇 |
1976年 | 11篇 |
1975年 | 6篇 |
1969年 | 1篇 |
排序方式: 共有484条查询结果,搜索用时 15 毫秒
71.
72.
73.
Klatskin tumors of the bile ducts: sonographic appearance 总被引:4,自引:0,他引:4
The authors present 3 cases of surgically proved Klatskin tumor diagnosed by ultrasound alone. Sonographic features of these tumors include (a) dilatation of the intrahepatic biliary ducts but not the extrahepatic duct, (b) non-union of the right and left hepatic ducts, and (c) small, solid masses at the hepatic hilus. Local spread to the liver may also be seen. If the pancreas appears normal and no primary tumor can be found, Klatskin tumor can be diagnosed with a high degree of accuracy. 相似文献
74.
75.
Parul J Shukla Savio G Barreto MMS Bedi N Bheerappa Adarsh Chaudhary MD Gandhi M Jacob S Jesvanth DG Kannan Vinay K Kapoor A Kumar KK Maudar Hariharan Ramesh RA Sastry Rajan Saxena Ajit Sewkani S Sharma Shailesh V Shrikhande A Singh Rajneesh K Singh R Surendran Subodh Varshney V Verma V Vimalraj 《HPB : the official journal of the International Hepato Pancreato Biliary Association》2009,11(8):638-644
Background:
There have been an increasing number of reports world-wide relating improved outcomes after pancreatic resections to high volumes thereby supporting the idea of centralization of pancreatic resectional surgery. To date there has been no collective attempt from India at addressing this issue. This cohort study analysed peri-operative outcomes after pancreatoduodenectomy (PD) at seven major Indian centres.Materials and Methods:
Between January 2005 and December 2007, retrospective data on PDs, including intra-operative and post-operative factors, were obtained from seven major centres for pancreatic surgery in India.Results:
Between January 2005 and December 2007, a total of 718 PDs were performed in India at the seven centres. The median number of PDs performed per year was 34 (range 9–54). The median number of PDs per surgeon per year was 16 (range 7–38). Ninety-four per cent of surgeries were performed for suspected malignancy in the pancreatic head and periampullary region. The median mortality rate per centre was four (range 2–5%). Wound infections were the commonest complication with a median incidence per centre of 18% (range 9.3–32.2%), and the median post-operative duration of hospital stay was 16 days (range 4–100 days).Conclusions:
This is the first multi-centric report of peri-operative outcomes of PD from India. The results from these specialist centers are very acceptable, and appear to support the thrust towards centralization. 相似文献76.
This prospective study analyzes the neonatal outcome in deliveries complicated by meconium stained amniotic fluid. In a study of 1000 live born deliveries, meconium staining of amniotic fluid was seen in 50 (5%) deliveries. Out of these, 20 newborns (40%) developed classical signs of meconium aspiration syndrome and were managed according to a predetermined protocol. Multiparity, term deliveries, use of sedatives in mother, intrauterine growth retardation and prolonged labour were some of the risk factors for development of meconium aspiration syndrome in newborns. This study highlights the need for review of management protocol in newborns after meconium staining of the amniotic fluid, including the use of prophylactic antibiotics.KEY WORDS: Amniotic fluid, Delivery, Meconium aspiration, Respiratory distress syndrome 相似文献
77.
Fas分子与肝细胞凋亡 总被引:7,自引:4,他引:3
近年来细胞分子生物学领域中的两个重要进展,即细胞凋亡概念的提出和Fas分子的分离与鉴定对肝病的研究有重要影响,加深了人们对肝细胞损伤与死亡的认识.1993年Ogasawaraetal[1]进行的Fas单抗毒性实验证实了Fas分子系统在肝细胞凋亡或损伤... 相似文献
78.
79.
Cutaneous Crohn''s disease mimicking Melkersson–Rosenthal syndrome: treatment with methotrexate 总被引:1,自引:0,他引:1
V Tonkovic-Capin† SS Galbraith† RS Rogers III ‡ DG Binion§ KB Yancey† 《Journal of the European Academy of Dermatology and Venereology》2006,20(4):449-452
A woman with a 5-year history of unilateral orofacial granulomatosis required repeated evaluations (including sequential colonoscopies) to establish the diagnosis of cutaneous Crohn's disease, a condition that proved responsive to low doses of oral methotrexate administered weekly. To our knowledge this is the first report describing the use of methotrexate for treatment of orofacial granulomatosis caused by underlying Crohn's disease. 相似文献
80.
ObjectiveTo investigate the neurotransmitter enzyme Acetylcholinesterase (AChE) activity in the brain and blood of rats infected with Trypanosoma congolense (T. congo).MethodsPresence and degree of parasitemia was determined daily for each rat by the rapid matching method. AChE activity was determined by preparing a reaction mixture of brain homogenate and whole blood with 5, 5-dithiobisnitrobenzioc acid (DTNB or Ellman's reagent) and Acetylthiocholine (ATC). The increase in absorbance was recorded at 436 nm over 10 min at 2 min intervals. Trypanosome species identification (before inoculation and on day 10 post infection) was done by Polymerase chain reaction using specific primers.ResultsThe AChE activity in the brain and blood decreased significantly as compared with the uninfected control. The AChE activity dropped to 0.32 from 2.20 μmol ACTC min?1mg protein?1 in the brain and 4.57 to 0.76 μmol ACTC min-1mg protein?1 in the blood. The animals treated with Diminaveto at 3.5 mg/kg/d were observed to have recovered significantly from parasitemia and were able to regain AChE activity in the blood but not in the brain as compared to the control groups. We also observed, that progressive parasitemia resulted to alterations in PCV, Hb, RBC, WBC, neurophils, total protein, lymphocytes, monocytes and eosinophil in acute infections of T. congo. Polymerase chain reaction (PCR) of infected blood before inoculation and on day 10 post infection revealed 600 bp on agarose gel electrophoresis.ConclusionsThis finding suggest that decrease in AChE activity increases acetylcholine concentration in the synaptic cleft resulting to neurological failures in impulse transfer in T. congo infection rats. 相似文献