全文获取类型
收费全文 | 5392篇 |
免费 | 508篇 |
国内免费 | 13篇 |
专业分类
耳鼻咽喉 | 94篇 |
儿科学 | 269篇 |
妇产科学 | 177篇 |
基础医学 | 868篇 |
口腔科学 | 70篇 |
临床医学 | 790篇 |
内科学 | 1102篇 |
皮肤病学 | 74篇 |
神经病学 | 333篇 |
特种医学 | 211篇 |
外国民族医学 | 2篇 |
外科学 | 547篇 |
综合类 | 83篇 |
一般理论 | 12篇 |
预防医学 | 582篇 |
眼科学 | 47篇 |
药学 | 346篇 |
中国医学 | 3篇 |
肿瘤学 | 303篇 |
出版年
2022年 | 41篇 |
2021年 | 83篇 |
2020年 | 45篇 |
2019年 | 76篇 |
2018年 | 95篇 |
2017年 | 62篇 |
2016年 | 84篇 |
2015年 | 90篇 |
2014年 | 95篇 |
2013年 | 136篇 |
2012年 | 212篇 |
2011年 | 226篇 |
2010年 | 124篇 |
2009年 | 120篇 |
2008年 | 255篇 |
2007年 | 236篇 |
2006年 | 213篇 |
2005年 | 200篇 |
2004年 | 224篇 |
2003年 | 201篇 |
2002年 | 191篇 |
2001年 | 183篇 |
2000年 | 213篇 |
1999年 | 149篇 |
1998年 | 91篇 |
1997年 | 65篇 |
1996年 | 56篇 |
1995年 | 68篇 |
1994年 | 60篇 |
1993年 | 58篇 |
1992年 | 144篇 |
1991年 | 132篇 |
1990年 | 128篇 |
1989年 | 136篇 |
1988年 | 121篇 |
1987年 | 110篇 |
1986年 | 105篇 |
1985年 | 117篇 |
1984年 | 71篇 |
1983年 | 67篇 |
1982年 | 47篇 |
1981年 | 49篇 |
1979年 | 67篇 |
1978年 | 58篇 |
1977年 | 57篇 |
1976年 | 44篇 |
1975年 | 40篇 |
1974年 | 66篇 |
1973年 | 44篇 |
1970年 | 41篇 |
排序方式: 共有5913条查询结果,搜索用时 0 毫秒
91.
We describe an additional case of spastic paretic hemifacial contracture, an uncommon condition characterized by sustained unilateral contraction of the facial muscles associated with mild ipsilateral facial paresis. This entity has only rarely been associated with multiple sclerosis (MS) and can be mistaken for hemifacial spasm. Early consideration of MS in the differential diagnosis of young patients admitted with these symptoms is essential. 相似文献
92.
B. H. Singsen A. S. Isaacson B. H. Bernstein M. J. Patzakis H. K. Kornreich K. K. King V. Hanson 《Arthritis \u0026amp; Rheumatology》1978,21(4):401-406
Fourteen children with juvenile rheumatoid arthritis and two with ankylosing spondylitis received 29 total hip replacements (THR). The ages at THR were 12 to 18 years, the median duration of prior hip disease was 7.1 years, and the minimum followup was one year (range 1–4 years, median 2.2 years). The primary indication for THR was pain in 5 hips and severe malposition or flexion contractures in 24 hips. (Sixteen of these also had some degree of pain.) All 29 hips demonstrated improved postoperative range of motion, and all were free of pain. In children, active rheumatic disease in other joints, prosthesis longevity, and possible lack of adequate motivation all merit special consideration prior to THR, but the results are encouraging. 相似文献
93.
Michael Sugarman Dennis G. Stobie Francisco P. Quismorio Roger Terry Virgil Hanson 《Arthritis \u0026amp; Rheumatology》1977,20(5):1125-1128
Five children with an inflammatory monarthritis due to penetration of the joint by plant thorns are presented. The clinical presentation was that of a transient acute synovitis followed by a relatively asymptomatic period, and later by chronic arthritis often after the thorn injury was forgotten. Histopathology demonstrated a granulomatous synovitis. Polarized light microscopy facilitated identification of the plant tissue within the synovium. Conservative medical therapy was ineffective, but surgical excision of the affected synovium resulted in normal joint function. The differential diagnosis of monarthritis in children is extensive, and awareness of this condition is necessary to elicit a comprehensive history and to avoid delay in treatment. 相似文献
94.
Lin PH Chronos NA Marijianowski MM Chen C Conklin B Bush RL Lumsden AB Hanson SR 《The Journal of surgical research》2003,112(1):84-90
PURPOSE: This study evaluates the effect of heparin-coated balloon-expandable stents on intimal hyperplasia following carotid artery stenting in a baboon model. MATERIALS AND METHODS: Balloon-expandable (Palmaz-Schatz) stents were placed in bilateral common carotid arteries in 26 male baboons (mean weight: 11.3 kg). In each animal, a heparin-coated (HC) carotid stent was placed on one side, whereas the contralateral carotid artery received an uncoated stent that served as a control. The carotid stents were harvested at 30 days (n = 13) and 90 days (n = 13). Arteriography was performed to assess the carotid patency, and intravascular ultrasound was used to determine neointimal and luminal areas. Histological, morphometric analysis, and scanning electron microscopy were performed in the stented carotid arteries. RESULTS: One animal was excluded in each of the 1-month and 3-month groups because of premature death. Ten control (83%) and 11 HC stents (92%) remained patent in the 30-day group. In contrast, 10 control (83%) and 10 HC stents (83%) remained patent in the 90-day group. Morphometric analysis of the 30-day group showed the HC-stented carotid arteries had larger luminal areas (13%, P < 0.05), less neointimal areas (38%, P < 0.05), less neointimal/media ratios (53%, P < 0.05), and equivalent medial areas (NS) when compared with the control group. Morphometric analysis of the 90-day data showed the HC-stented carotid arteries had less neointimal areas (38%, P < 0.05) and less neointimal/media ratios (48%, P < 0.05), whereas the luminal areas and medial areas remained equivalent (NS) when compared with the control group. CONCLUSIONS: Carotid stenting using heparin-coated stents reduces early intimal hyperplasia in a baboon model. This approach may represent a useful strategy for improving luminal patency in endovascular carotid intervention. 相似文献
95.
96.
97.
98.
Abigail A. Fagan Michael W. Arthur Koren Hanson John S. Briney J. David Hawkins 《Prevention science》2011,12(3):223-234
This paper describes findings from the Community Youth Development Study (CYDS), a randomized controlled trial of the Communities
That Care (CTC) prevention system, on the adoption and implementation fidelity of science-based prevention programming in
24 communities. Data were collected using the Community Resource Documentation (CRD), which entailed a multi-tiered sampling
process and phone and web-based surveys with directors of community-based agencies and coalitions, school principals, service
providers, and teachers. Four years after the initiation of the CTC prevention system, the results indicated increased use
of tested, effective prevention programs in the 12 CTC intervention communities compared to the 12 control communities, and
significant differences favoring the intervention communities in the numbers of children and families participating in these
programs. Few significant differences were found regarding implementation quality; respondents from both intervention and
control communities reported high rates of implementation fidelity across the services provided. 相似文献
99.
100.
Genetic variation in UCP2 (uncoupling protein-2) is associated with energy metabolism in Pima Indians 总被引:10,自引:0,他引:10
Aims/hypothesis Uncoupling protein-2 (UCP2) is thought to play a role in insulin secretion and the development of obesity. In this study, we investigated the effects of genetic variation in UCP2 on type 2 diabetes and obesity, as well as on metabolic phenotypes related to these diseases, in Pima Indians.Methods The coding and untranslated regions of UCP2, and approximately 1 kb of the 5 upstream region, were sequenced in DNA samples taken from 83 extremely obese Pima Indians who were not first-degree relatives.Results Five variants were identified: (1) a –866G/A in the 5 upstream region; (2) a G/A in exon 2; (3) a C/T resulting in an Ala55Val substitution in exon 4; and (4, 5) two insertion/deletions (ins/del; 45-bp and 3-bp) in the 3 untranslated region. Among the 83 subjects whose DNA was sequenced, the –866G/A was in complete genotypic concordance with the Ala55Val and the 3-bp ins/del polymorphism. The G/A polymorphism in exon 2 was extremely rare. To capture the common variation in this gene for association analyses, the –866G/A variant (as a representative of Ala55Val and the 3-bp ins/del polymorphism) and the 45-bp ins/del were also genotyped for 864 full-blooded Pima Indians. Neither of these variants was associated with type 2 diabetes or body mass index. However, in a subgroup of 185 subjects who had undergone detailed metabolic measurements, these variants were associated with 24-h energy expenditure as measured in a human metabolic chamber (p=0.007 for the 45-bp ins/del and p=0.03 for the –866G/A after adjusting for age, sex, family membership, fat-free mass and fat mass).Conclusions/interpretation Our data indicate that variation in UCP2 may play a role in energy metabolism, but this gene does not contribute significantly to the aetiology of type 2 diabetes and/or obesity in Pima Indians. 相似文献