首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   6564篇
  免费   338篇
  国内免费   39篇
耳鼻咽喉   53篇
儿科学   101篇
妇产科学   129篇
基础医学   761篇
口腔科学   146篇
临床医学   481篇
内科学   1757篇
皮肤病学   96篇
神经病学   342篇
特种医学   119篇
外科学   868篇
综合类   39篇
一般理论   1篇
预防医学   192篇
眼科学   262篇
药学   824篇
中国医学   15篇
肿瘤学   755篇
  2023年   42篇
  2022年   105篇
  2021年   121篇
  2020年   62篇
  2019年   100篇
  2018年   119篇
  2017年   97篇
  2016年   114篇
  2015年   112篇
  2014年   134篇
  2013年   188篇
  2012年   346篇
  2011年   331篇
  2010年   197篇
  2009年   156篇
  2008年   261篇
  2007年   301篇
  2006年   280篇
  2005年   281篇
  2004年   258篇
  2003年   287篇
  2002年   268篇
  2001年   283篇
  2000年   273篇
  1999年   249篇
  1998年   83篇
  1997年   49篇
  1996年   59篇
  1995年   53篇
  1994年   39篇
  1993年   46篇
  1992年   149篇
  1991年   121篇
  1990年   129篇
  1989年   155篇
  1988年   140篇
  1987年   128篇
  1986年   134篇
  1985年   116篇
  1984年   76篇
  1983年   49篇
  1982年   34篇
  1980年   26篇
  1979年   42篇
  1978年   23篇
  1977年   35篇
  1974年   26篇
  1973年   31篇
  1972年   29篇
  1968年   23篇
排序方式: 共有6941条查询结果,搜索用时 15 毫秒
991.
Ossifying fibroma in maxilla. Report of case   总被引:1,自引:0,他引:1  
Since first reported by Montgomery in 1927, ossifying fibroma, a benign neoplasm of bone or bone tissue, has been the subject of numerous studies. In the present paper, a case of ossifying fibroma in a woman is presented. The woman was 49 years old. She visited our clinic with a complaint of swelling in the right maxillary region. Thorough examinations were conducted. From X-ray, CT, scintigraphy and biopsy findings, the case was diagnosed as ossifying fibroma. Under a general anesthetic, the tumor was extirpated. It measured 40 x 40 x 60mm. It's weight, including that of teeth, was 60.5 g. Histopathological examination revealed fibroblasts and hard, bone-like masses of varying shapes in the connective tissue. Nearly one year has elapsed since the surgical operation. The patient is doing well. Since 1957, a total of 107 cases of ossifying fibroma have been reported in Japan. The ages of the patients were mostly between 10 and 49. By sex, 42 were male and 65 female. By region, in 28 case, fibroma occurred in the maxillary part, 68 in the mandibular part, and 11 in the region extending from maxillary to mandibular area. More 70% of the cases were fibroma originating in the molar area.  相似文献   
992.
Sixteen cases with ovarian immature teratoma received our managements have been reviewed. After exhaustive tissue examination, those neoplasms were graded histologically according to the criteria proposed by Thurlbeck and Scully, in addition, to exclude the mixed germ cell tumors, alfa fetoprotein stainings by PAP method were performed. Ten of all patients are alive without any signs of recurrence and none of grade 3 patients could survive. In our small series, the histologic grade seemed to correlate with the prognosis. Now-a-days the prognostic significance of the grading systems, however, still remains controversial, and it is discussed in this paper. Of particular interest is that the immature teratoma containing glioblastoma element took most fulminant clinical course. It was suggested that special attention should be paid to the histologic components of glioblastoma in the neoplasm. Serum alfa feto-protein level, elevated in two cases, was not associated with the clinical situation and AFP value appears to have questionable diagnostic importance as the tumor marker. Although we had no standard chemotherapeutic programs for immature teratomas, it is believed that the more aggressive surgery followed by good combination chemotherapy brings better prognosis.  相似文献   
993.
994.
In recent years, chemotherapy has markedly advanced after cisplatin became available. In addition, it has recently been found that the efficacy of chemotherapy differs according to the diameter of the residual tumor (less than 2 approximately 3 cm). For these reasons, debulking or cytoreduction surgery has been frequently carried out in advanced cancer cases to reduce the diameter of tumors. Basic procedures adopted by an increasing number of medical institutions are bilateral adnexectomy + simple total hysterectomy and omentectomy. In addition, since lymph node metastasis is found even in early cancer cases, dissection of lymph nodes extending from the pelvic lymph node to the paraaortic lymph node is now considered to be essential, and is referred to also by the FIGO's new classification of cancer stages. SLO is also important in judging the necessity of excising a residual tumor and assessing therapeutic efficacy. In chemotherapy, high effectiveness rates have been reported chiefly for cisplatin + CAP therapy in epithelial tumor cases and cisplatin + VAC or VBP therapy in germ cell tumor cases. However, since the effect of cisplatin in second and third lines is not satisfactory, development of new platinum compounds and studies of more effective regimens (such as massive cisplatin therapy) are now being performed. Radiation therapy, on the other hand, is merely an auxiliary therapy at present.  相似文献   
995.
A novel enzyme immunoassay of anti-insulin IgG in human serum is described. A serum sample containing anti-insulin IgG was treated with dextran-charcoal at pH 6.0 to remove endogenous insulin and subsequently incubated with dinitrophenyl biotinyl nonspecific rabbit IgG-insulin conjugate. The reaction mixture was further incubated with a rabbit (antidinitrophenyl bovine serum albumin) IgG-coated polystyrene ball to trap the complex formed between anti-insulin IgG and the conjugate. After washing to eliminate nonspecific IgG in the test serum, the polystyrene ball was incubated with dinitrophenyl-L-lysine to elute the complex. The eluate was incubated with an avidin-coated polystyrene ball. Finally, the amount of human anti-insulin IgG in the complex trapped onto the avidin-coated polystyrene ball was measured by incubation with rabbit (antihuman IgG (γ-chain)) Fab'-peroxidase conjugate. This enzyme immunoassay was 1,000-fold more sensitive than the conventional enzyme immunoassay, in which an insulin-bovine serum albumin-coated polystyrene ball was incubated with a serum sample containing anti-insulin IgG and subsequently with rabbit (antihuman IgG (γ-chain)) Fab'-peroxidase conjugate. The principle of the novel enzyme immunoassay can be used to more sensitively measure antibodies for most kinds of haptens and antigens than the conventional enzyme immunoassay.  相似文献   
996.
Summary Muscle biopsies from 16 patients with cytochromec oxidase (CCO) deficiency were examined morphologically. Two siblings had the fatal infantile form. The muscle of the older sister at the age of 5 months had numerous ragged-red fibers (RRF) and increased numbers of lipid droplets; at 28 days the brother had no RRF suggesting that the RRF formed later than 28 days. The muscle pathology in two patients with the benign infantile form improved as they grew older; numbers of RRF, lipid droplets and glycogen particles decreased and CCO activity increased in the second biopsy. In the encephalomyopathic form, RRF were seen in 5 of 12 muscles mostly in patients more than 6 years of age. Muscle spindles and blood vessel walls in the biopsies from three patients with rapid clinical aggravation had no CCO activity, suggesting that enzyme activity differed from tissue to tissue (tissue specificity).Supported in part by a Grant-in-Aid for Scientific Research on Priority Areas (No. 62617523) from the Ministry of Education, Science and Culture of Japan  相似文献   
997.
998.
999.
Ulcerative colitis is a borderline disease between medicine and surgery and ultimate evaluation of medical or surgical therapy remains to be settled. Except for the absolute indication for operation (toxic dilatation, perforation, bleeding and etc.), it is not always easy to consider surgery for this disease because so many factors influence its clinical course. Nevertheless, a prudent decision regarding surgery seems mandatory for a reasonable surgical therapy with a low mortality and high curability that enables an earlier rehabilitation and more complete social activity. The total number of primary operative cases of ulcerative colitis in our clinic over a period of March 1954 through the end of December 1983 was 30. A comparison of our experience up to the end of 1965 and since then has shown an operative mortality of 2/14 in the first and 1/16 in the second period, and that all these 3 deaths were through an emergency operation but not through 29 cases of elective surgery. It is emphasized that one of the most important factors influencing outcome of operation is whether or not it is undertaken as an urgent surgery during a hard time of the disease that has failed to respond to intensive medical treatment.  相似文献   
1000.
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号