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151.
本文报告260例恶性肿瘤患者血清维生素A、E、C水平的测定结果。发现除慢性白血病外,蓁7种恶性肿瘤患者血清维生素A水平平均显著低于健康人(P<0.01);急性白血,肝癌、食管癌患者血清维生素E水平显著低于健康人(P<0.05);急性粒细胞白血病、急性单核细胞白血病、肝癌患者血维生素C水平显著低于健康人(P<0.01)。本研究工作为维生素A、E、C药物在肿瘤临床上的应用提供了参考。 相似文献
152.
我们对30例住院病人用荧光分光光度法测定了不同烧伤时间、不同烧伤指数(BI)血儿茶酚胺类(CA)释放量,以期了解病人的应激状况,同时测血糖(BS)和用放射免疫法测血胰岛素(SI)。结果表明烧伤后CA类释放是持续性的,且有休克和感染两个高峰(P<0.05,P<0.01);CA类释放主要是去甲肾上腺素(NE)的持续性增加,是正常量的两倍以上。休克期CA类释放如不增加,脓毒症阶段肾上腺素(E)与去甲肾上腺素从高值骤然下降,且低于休克期。提示:交感-肾上腺系统已处于衰竭状态,死亡似不可避免,而胰岛素分泌正常或相对不足。因此我们认为,CA类释放增加、糖原异生、胰岛β细胞分泌受抑制,是烧伤后全过程内分泌变化的主要原因。扩容纠酸、早期切痂预防感染以及使用抗CA类药物是防治的主要措施。 相似文献
153.
Central sensory and motor conduction in vitamin B12 deficiency. 总被引:7,自引:0,他引:7
V Di Lazzaro D Restuccia D Fogli R Nardone S Mazza P Tonali 《Electroencephalography and clinical neurophysiology》1992,84(5):433-439
Four patients with subacute combined degeneration were studied through upper and lower limb SEPs recorded with a non-cephalic reference montage and through cortical and spinal magnetic stimulation. Clinical signs were confined to the lower limbs in 3 patients; the remaining patient presented only paraesthesiae in 4 limbs. Median nerve SEPs showed a normal cervical N13 response with a significant increase of central conduction time concerning exclusively the P9-P14 interpeak interval. Central motor conduction to upper and lower limb muscles was abnormal. Nerve conduction studies provided no evidence of peripheral nerve involvement. These electrophysiological findings suggest that in vitamin B12 deficiency the higher segments of the cervical cord are usually affected first and that central sensory and motor conduction studies are sensitive methods for detecting such damage. 相似文献
154.
X F Sun H Zhang X C Wu Y M Han G Q Hou M S Xian 《Acta oncologica (Stockholm, Sweden)》1992,31(1):37-40
The microcirculatory architecture of normal tissue, transitional mucosa and adenocarcinoma of the human colon was investigated with microvascular corrosion casting (MVCC) combined with scanning electron microscopy (SEM). The study showed that the capillaries within the normal mucosa were arranged in a regular hexagonal pattern around the mucosal glands and that the microvessels of transitional mucosa mostly had lost the typical hexagonal pattern and become slightly wider in diameter. The microvessels in the tumor periphery were increased in number and disorganized, and presented large variation in morphology with claw-like formations, widened sinuses, diverticula and appendixoid patterns. Microvessels were lacking in the central areas of tumors. These morphological alterations may serve as additional indicators of tumor development. 相似文献
155.
白细胞介素—2新的功能位点及其中枢镇痛作用 总被引:2,自引:0,他引:2
白细胞介素-2(IL-2)不仅是重要的免疫调节因子,而且还具有重要的中枢调节作用。本实验以钾离子透入引起大鼠甩尾反应为指标,发现侧脑室注射IL—2能显著提高动物痛阈,并能被纳洛酮所阻断,表示IL-2的中枢镇痛作用可能与阿片受体有关。利用基因定位突变技术获得的无免疫活性IL-2实查体仍具有中枢镇痛作用,表明IL—2分子上发挥镇痛和免疫调节作用的功能位点是相互独立的。纳洛酮能够阻断IL—2的中枢镇痛作用,而不能影响IL—2增殖CTLL-2细胞的作用,提示IL-2发挥镇痛和免疫调节作用可能通过不同的受体途径。IL-2分子中第45位Tyr残基突变为Val后,虽仍保留了免疫活性,但丧失了镇痛功能,表示45位Tyr残基是IL—2发挥中枢镇痛功能的关键残基之一。我们推测IL—2的镇痛功能位点可能在IL—2分子中第45位Tyr残基附近区域。 相似文献
156.
157.
B B Toner E Koyama P E Garfinkel K N Jeejeebhoy I Di Gasbarro 《International journal of psychiatry in medicine》1992,22(1):99-103
The Marlowe-Crowne Social Desirability Scale, a 33-item self-report questionnaire, was administered to an age-matched sample of twenty-five irritable bowel syndrome (IBS) patients, twenty-four psychiatric patients meeting a diagnosis of major depression, and nineteen controls. As predicted, planned comparisons analysis showed a significant group effect: IBS group scores were significantly higher than both depressed and control group scores (p less than .05). Implications of this social desirability response set for the psychological assessment and treatment of IBS are discussed. 相似文献
158.
A Oehling B García F Santos H Córdoba I Diéguez M Fernández M L Sanz 《Journal of investigational allergology & clinical immunology》1992,2(2):78-83
We studied the histories of patients who had visited our Department during the last 5 years, presenting food allergy with exclusively respiratory symptoms (18.5%). We studied the correlation between IgE levels and the histamine release test and the type of food implicated. Seventy-seven percent of patients presented sensitization to one food, and 23% presented polysensitization. We found that foods such as snails and eggs have a strong predilection for the bronchial tree as the shock organ. High total IgE was found in 85.2% of patients. The histamine release test was positive in 66% of cases. We conclude that this is a highly sensitive method for the in vitro diagnosis of food allergy. 相似文献
159.
160.
The Authors report a case of bilateral ureteropelvic junction obstruction in a pregnant woman at to 20th week of gestation. The pathology arose suddenly during the second trimester. An anhydramnios was picant and the enlarged kidneys filled the entire fetal abdomen. The woman decided for abortion. The Authors describe the etiopathology and management of this disease. 相似文献