特发性单侧透明肺的影像诊断

目的分析特发性单侧透明肺的影像诊断。方法本组共29例特发性单侧透明肺。29例均拍胸部正侧位片,其中19例行电视透视,14例行胸部CT扫描,2例做支气管造影,1例行体层摄影,1例行肺动脉、主动脉造影。结果29例患肺透亮度增大,其中左全肺23例,左下叶5例,左全肺并右肺中下叶1例。左肺门及肺血管性纹理细小。21例左侧胸廓轻度塌陷,21例纵隔气管左偏,19例电视透视见纵隔摆动,14例CT扫描见左肺动脉细小,其中主干细小9例,左肺下叶动脉细小5例。12例见右下肺动脉干增粗,5例动脉段延长,7例肺动脉段突出,4例心脏增大,19例支气管扩张。结论影像学检查是特发性单侧透明肺的关键确诊手段。     

次黄嘌呤－内源性单胺氧化酶（MAO）抑制剂样活性的研究

体外实验证明，嘌呤类化合物对Ｂ－型ＭＡＯ活性有不同程度的抑制作用，其抑制强度为：次黄嘌呤＞鸟便嘌呤＞腺嘌呤＞嘌呤＞黄嘌呤＞尿酸。老龄小鼠（１８月龄）的血、脑及肝组织ＭＡＯ活性较年青小鼠（１月龄）显著升高，而上述组织中嘌呤类化合物的含量却随年龄增加而降低。老龄小鼠肝线粒体外膜ＭＡＯ提取物中次黄嘌呤含量明显低于年青小鼠，但两组ＭＡＯ中腺嘌呤含量却无明显差异。离体温孵实验证明［３Ｈ］次黄嘌呤与老龄小鼠脑和肝ＭＡＯ结合量明显高于年青小鼠。体内结合实验结果亦表明［３Ｈ］次黄嘌呤与老龄小鼠肝ＭＡＯ结合量高于年青小鼠外，并证明［３Ｈ］次黄嘌呤的结合部位是在ＭＡＯ酶蛋白上，而非在辅基上。此外，多次灌服次黄嘌呤２００ｍｇ／ｋｇ可明显抑制老龄小鼠脑ＭＡＯ－Ｂ活性，并使单胺类物质（５－ＨＴ、ＤＡ）含量明显增加。     

美白中药之水及乙醇提取物对酪氨酸酶抑制功效之比较

 目的　鲁府禁方内之八白散为我国有名的美容方剂,有着使皮肤白晰的作用。本研究旨在观察方中个别中药水提物之活性,及探讨使用80%乙醇作替代提取媒介之可行性。方法　通过酪氨酸酶活性之抑制测试,并用曲酸作阳性对照,来评价个别中药水提物之有效程度。并将抑制作用明显较高的中药用80%乙醇提取,以和其水提物作一对比。结果　白水蔹提物的抑制作用最高,白芷及白及之水提物也有相当高的抑制效果。但白蔹、白芷及白及之80%乙醇提物抑制酪氨酸酶效果较差,其IC50比水提物之数值大5.9～23.8倍左右。结论　在提取白蔹、白芷及白及作美白用途时,在单纯考虑其提取物生物活性之基础上,水比80%乙醇为更好的提取媒介。     

Effect of auricular acupuncture on oxygen consumption of boxing athletes

Boxing is an official sport at the 2008 Beijing Olympic Games and the fast development of world-class high strength training and sport science has made a significant impact on scientific training. Boxing needs high cardio-respiratory function, speed, muscle strength, and anaerobic and intensive physical demands including weight control covering the grading of athlete's.     

Successful Coronary Stent Implantation Using Local Nitric Oxide Donor Delivery

With the introduction of high pressure balloon inflations and antiplatelet therapy, the incidence of stent thrombosis has been markedly reduced, but the incidence of late stent restenosis has not. A new strategy may be local drug delivery, which maintains sustained local concentration and limits systemic complications. To evaluate the efficacy of local nitric oxide (NO) donor delivery on stent thrombosis and complications, local NO donor delivery was performed in stented patients. NO donor (2.0-mg molsidomine) was delivered (1.0 mL/min > 10 min) using the Dispatch Catheter after predilation of target lesions in 13 patients (6 angina, 7 myocardial infarction, age 53.1 ± 11.4 years). After local NO donor delivery, Palmaz-Schutz stents were placed using standard methods. Follow-up coronary angiograms were performed 48 hours and 6 months after stenting. None of the patients had hypotensive effects, ischemic symptoms, or ECG changes during and after local NO donor delivery. APTT and CK values were unchanged at 3 and 24 hours after local NO donor delivery and stenting. Follow-up coronary angiograms at 48 hours and 6 months showed all stents patent with TIMI III flow and without intrastent thrombus. No target lesion revascularization and 100% event-free survival were observed during the 6-month clinical follow-up period. Intracoronary stenting may be performed safely and effectively by local NO donor delivery prior to stent implantation.