全文获取类型
收费全文 | 1076篇 |
免费 | 70篇 |
专业分类
耳鼻咽喉 | 7篇 |
儿科学 | 16篇 |
妇产科学 | 11篇 |
基础医学 | 115篇 |
口腔科学 | 8篇 |
临床医学 | 76篇 |
内科学 | 224篇 |
皮肤病学 | 30篇 |
神经病学 | 107篇 |
特种医学 | 22篇 |
外科学 | 71篇 |
综合类 | 22篇 |
预防医学 | 227篇 |
眼科学 | 5篇 |
药学 | 33篇 |
肿瘤学 | 172篇 |
出版年
2023年 | 7篇 |
2022年 | 27篇 |
2021年 | 32篇 |
2020年 | 24篇 |
2019年 | 40篇 |
2018年 | 41篇 |
2017年 | 30篇 |
2016年 | 29篇 |
2015年 | 21篇 |
2014年 | 24篇 |
2013年 | 30篇 |
2012年 | 56篇 |
2011年 | 44篇 |
2010年 | 13篇 |
2009年 | 32篇 |
2008年 | 46篇 |
2007年 | 57篇 |
2006年 | 60篇 |
2005年 | 69篇 |
2004年 | 51篇 |
2003年 | 32篇 |
2002年 | 37篇 |
2001年 | 51篇 |
2000年 | 31篇 |
1999年 | 43篇 |
1998年 | 14篇 |
1997年 | 8篇 |
1996年 | 15篇 |
1995年 | 4篇 |
1994年 | 9篇 |
1992年 | 10篇 |
1991年 | 14篇 |
1990年 | 12篇 |
1988年 | 8篇 |
1987年 | 4篇 |
1986年 | 11篇 |
1985年 | 7篇 |
1984年 | 8篇 |
1983年 | 7篇 |
1981年 | 8篇 |
1980年 | 4篇 |
1978年 | 5篇 |
1977年 | 4篇 |
1975年 | 6篇 |
1974年 | 7篇 |
1973年 | 11篇 |
1972年 | 6篇 |
1971年 | 7篇 |
1970年 | 4篇 |
1967年 | 4篇 |
排序方式: 共有1146条查询结果,搜索用时 0 毫秒
31.
32.
33.
Plasma adrenomedullin and obstructive sleep apnea 总被引:2,自引:0,他引:2
Wolk R Svatikova A Otto ME Hoffmann MS Duenwald CJ Somers VK 《American journal of hypertension》2004,17(1):74-76
BACKGROUND: Obstructive sleep apnea (OSA) is associated with hypertension. The vasorelaxing peptide adrenomedullin (ADM) may counteract effects of OSA-induced release of vasopressor substances. METHODS: Plasma ADM levels were measured at 9:30 PM, 2:00 AM (after 4 to 5 h of untreated OSA), and 6:00 AM (after 4 h of continuous positive airway pressure treatment) in 15 OSA patients and in 10 controls. RESULTS: Baseline ADM levels were similar in the OSA and control groups (28.7 +/- 6.7 v 27.7 +/- 6.4 pg/mL, respectively), did not change overnight in either group, and were not affected by continuous positive airway pressure. CONCLUSIONS: OSA does not exert any significant acute or chronic effects on plasma ADM levels. 相似文献
34.
35.
Steven E. Arnold Natalia Louneva Kajia Cao Li-San Wang Li-Ying Han David A. Wolk Selamawit Negash Sue E. Leurgans Julie A. Schneider Aron S. Buchman Robert S. Wilson David A. Bennett 《Neurobiology of aging》2013
Although neuritic plaques and neurofibrillary tangles in older adults are correlated with cognitive impairment and severity of dementia, it has long been recognized that the relationship is imperfect, as some people exhibit normal cognition despite high levels of Alzheimer's disease (AD) pathology. We compared the cellular, synaptic, and biochemical composition of midfrontal cortices in female subjects from the Religious Orders Study who were stratified into three subgroups: (1) pathological AD with normal cognition (“AD-Resilient”), (2) pathological AD with AD-typical dementia (“AD-Dementia”), and (3) pathologically normal with normal cognition (“Normal Comparison”). The AD-Resilient group exhibited preserved densities of synaptophysin-labeled presynaptic terminals and synaptopodin-labeled dendritic spines compared with the AD-Dementia group, and increased densities of glial fibrillary acidic protein astrocytes compared with both the AD-Dementia and Normal Comparison groups. Further, in a discovery-type antibody microarray protein analysis, we identified a number of candidate protein abnormalities that were associated with a particular diagnostic group. These data characterize cellular and synaptic features and identify novel biochemical targets that may be associated with resilient cognitive brain aging in the setting of pathological AD. 相似文献
36.
Ian W. Holloway Eric Rice Jeremy Gibbs Hailey Winetrobe Shannon Dunlap Harmony Rhoades 《AIDS and behavior》2014,18(2):285-296
Young men who have sex with men (YMSM) are increasingly using mobile smartphone applications (“apps”), such as Grindr, to meet sex partners. A probability sample of 195 Grindr-using YMSM in Southern California were administered an anonymous online survey to assess patterns of and motivations for Grindr use in order to inform development and tailoring of smartphone-based HIV prevention for YMSM. The number one reason for using Grindr (29 %) was to meet “hook ups.” Among those participants who used both Grindr and online dating sites, a statistically significantly greater percentage used online dating sites for “hook ups” (42 %) compared to Grindr (30 %). Seventy percent of YMSM expressed a willingness to participate in a smartphone app-based HIV prevention program. Development and testing of smartphone apps for HIV prevention delivery has the potential to engage YMSM in HIV prevention programming, which can be tailored based on use patterns and motivations for use. 相似文献
37.
38.
39.
Liisa Byberg Andrea Bellavia Susanna C Larsson Nicola Orsini Alicja Wolk Karl Michaëlsson 《Journal of bone and mineral research》2016,31(12):2098-2105
A Mediterranean diet, known to have beneficial effects on cardiovascular health, may also influence the risk of hip fracture although previous studies present discrepant results. We therefore aimed to determine whether the rate of hip fracture was associated with degree of adherence to a Mediterranean diet. We combined two Swedish cohort studies consisting of 37,903 men and 33,403 women (total n = 71,333, mean age 60 years) free of previous cardiovascular disease and cancer who answered a medical and a food‐frequency questionnaire in 1997. A modified Mediterranean diet score (mMED; range, 0 to 8 points) was created based on high consumption of fruits and vegetables, legumes and nuts, whole grains, fermented dairy products, fish, and olive/rapeseed oil, moderate intake of alcohol, and low intake of red and processed meat. Incident hip fractures between January 1, 1998, and December 31, 2012, were retrieved from the National Patient Register. Hazard ratios (HRs) and 95% confidence intervals (CIs) adjusted for potential confounders were calculated using Cox proportional hazards regression. Differences in age at hip fracture were calculated using multivariable Laplace regression. During follow‐up, 3175 hip fractures occurred at a median age of 73.3 years. One unit increase in the mMED was associated with 6% lower hip fracture rate (adjusted HR = 0.94; 95% CI, 0.92 to 0.96) and with a 3‐month higher median age at hip fracture (50th percentile difference = 2.8 months; 95% CI, 1.4 to 4.2). Comparing the highest quintile of adherence to the mMED (6 to 8 points) with the lowest (0 to 2 points) conferred an adjusted HR of hip fracture of 0.78 (95% CI, 0.69 to 0.89) and a 12‐month higher median age of hip fracture (50th percentile difference = 11.6 months; 95% CI, 4.2 to 19.0). Results were similar in men and women. We conclude that higher adherence to a Mediterranean‐like diet is associated with lower risk of future hip fracture. © 2016 American Society for Bone and Mineral Research. 相似文献
40.
Caroline?NordenvallEmail author Viktor?Oskarsson Alicja?Wolk 《European journal of nutrition》2018,57(1):75-81