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81.
Aim: To investigate the inflammatory effect and testicular damage on rats exposed to low level of electromagnetic fields (EMF) at 2.45?GHz microwave radiation.

Methods: Twenty two Wistar rats were divided into two groups. Group 1 was the control group and not exposed to EMF. Group 2 was exposed to low level EMF (average E-field 3.68?±?0.36 V/m, whole body average SAR, 0.0233 W/kg, in 10?g tissue) at 2.45?GHz for 1?hour/day for 30 consecutive days. At the end of the study, interleukin-6 (IL-6), interleukin-10 (IL-10), interleukin-32 (IL-32), C-reactive protein (CRP) were measured in rat serum and IL-6, IL-10, IL-32 were measured in rat testis tissue. Furthermore, testicular tissues were evaluated histopathologically in terms of spermatogenesis and coagulation necrosis.

Results: Serum IL-6 and CRP levels were found to be significantly different in the study group compared to the control group (p?<?.05), but no significant difference was found in serum IL-10, IL-32 levels and testis tissue IL-6, IL-10, IL-32 levels compared to the control group (p?>?.05). On the other hand, histopathological evaluation of testicular tissue revealed a significant difference in necrosis and spermatogenesis when compared with the control group (p?<?.05).

Conclusions: It may be concluded that low level EMF at 2.45?GHz increases inflammation and testicular damage and negative impact on male reproductive system function.  相似文献   
82.
目的分析降钙素原、新喋呤与乳酸对脓毒血症患者预后评估的临床价值。方法按预后将95例脓毒血症患者分成生存组和死亡组,其中生存组65例,死亡组30例,将发病早期的降钙素原、新喋呤与乳酸水平和ACHEⅡ评分进行对比,通过建立ROC曲线探讨标记物对于预后评估的临床意义。结果分析得知3种标记物水平和APACHEⅡ评分在2组患者中差异均具有统计学意义(P0.05),并且3种标记物水平与APACHEⅡ评分具有明显的相关性;标记物阳性结果越多,病死率越高;3项标记物预测死亡的ROC曲线下面积在0.70~0.78之间。结论降钙素原、新喋呤与乳酸对脓毒血症患者的预后评估具有重要的临床研究价值,对患者的死亡具有较好的预测意义,并且联合检测能够提高预测的敏感程度。  相似文献   
83.
84.
This study is a prospective, consecutive, 3-year cohort study of women with back pain in an index pregnancy. The aim was to describe the physical status and disability among women with back pain 3 years after delivery. Pain was identified as lumbar back pain, posterior pelvic pain or combined lumbar as well as posterior pelvic pain. Previous studies have established that all three types of pain can be reduced by structured physiotherapy during pregnancy, and the beneficial effect may last for several years. Though it is known that some women have residual pain for a long time, the relative incidence of the three pain types and their degree of disability associated with each have never been reported. Neither has any study presented findings of a physical examination of women 3 years post partum with a focus on the type of pain. All women who were registered as having experienced back pain during an index pregnancy were interviewed by mail 3 years post partum. Women who had residual back pain filled in an additional questionnaire and were physically examined. Out of 799 pregnant women, 231 had some type of back pain during the index pregnancy, and 41 women had pain 3 years later. Women with combined lumbar and posterior pelvic pain were significantly more disabled ( P<0.05) and had significantly lower endurance in the lumbar back and hip abduction muscles ( P<0.01). Some 5% of all pregnant women, or 20% of all women with back pain during pregnancy, had pain 3 years later. The key problem may be poor muscle function in the back and pelvis.  相似文献   
85.
OBJECTIVE: To investigate whether patients with chronic obstructive pulmonary disease on long-term oxygen therapy would benefit from an early 8-week rehabilitation programme in terms of exercise performance, health-related quality of life and activities of daily living. METHODS: Two weeks after onset of oxygen therapy, 20 patients were randomized to rehabilitation (group A) or not (group B). Exercise performance was measured using a 6-minute walking test. Health-related quality of life was measured with the Chronic Respiratory Disease Questionnaire. Activity of daily living ability was measured with the Stanford Health Assessment Questionnaire. RESULTS: The mean 6-minute walking distance increased by 35% (p < 0.01) in group A after rehabilitation. The mean increase in group B was only 8% (n.s.). Patients in group A reported less overall dyspnoea after rehabilitation (p < 0.05) and, compared with group B, reported better activity of daily living ability (p < 0.01). CONCLUSION: Patients with chronic obstructive pulmonary disease on long-term oxygen treatment may improve their walking distance, experience less dyspnoea and improve activity of daily living ability with an early rehabilitation programme.  相似文献   
86.

Background  

Experiencing or being at risk of adverse reactions to certain food items is a common health issue, especially among children and adolescents. Research has shown that living with the risk of food reactions and always having to take measures to avoid certain food in one's diet has a negative impact on quality of life. The aim of this study was to illuminate adolescents' experiences of being food hypersensitive.  相似文献   
87.
SYNOPSIS
The prophylactic anti-migraine effect of atenolol was compared to placebo in a multicentre study on 63 patients with classical and/or common migraine. The study design was double-blind cross-over and patients were given atenolol 100 mg o.d. or matching placebo during a study treatment period of 24 weeks. The effect of atenolol was significantly better than that of placebo: integrated headache values were reduced in 70% of the patients (p = 0.004) and the proportion of days with headache was reduced in 59% of the patients (p = 0.010). Few side effects were reported with both atenolol and placebo. This study shows atenolol to be safe and effective in the prophylactic treatment of migraine.  相似文献   
88.

Background

Partial internal biliary diversion (PIBD) is an alternative approach for the treatment of devastating pruritus in patients with progressive familial intrahepatic cholestasis (PFIC). In these patients quality of life can be improved and progression of liver disease can be delayed while waiting for liver transplantation. The aim of our study was to evaluate six patients with PFIC who have undergone PIBD in long-term follow-up.

Methods

Retrospective review of the records of six patients who underwent PIBD for PFIC between 2008 and 2010 was conducted to evaluate age, growth, clinical and laboratory studies for long-term outcome.

Results

Serum postoperative bile acid levels were reduced from a mean 340.1 μmol/L (range 851–105) preoperatively to a mean of 96.3 μmol/L at postoperative fifth year. The difference between pre- and postoperative bile acid levels was statistically significant (p = 0.018). AST decreased from 79.1 U/L (range 43–150 U/L) to 64.6 U/L (range 18–172 U/L), ALT decreased from 102.8 U/L (range 35-270 U/L) to 84.6 U/L and total bilirubin decreased from 2.9 μmol/L (range 0.35–6.4 μmol/L) to 1.53 μmol/L (range 0.3–2.4). Again, the decrease in total bilirubin levels was significant (p = 0.043). Pruritus was diminished from a mean of + 4 (range 4–4) preoperatively to a mean of + 2 (4–0). One patient who underwent liver transplantation owing to relapsing pruritus died from postoperative sepsis in the early postoperative period at the fifth year after PBID. Five symptom-free patients have not required liver transplantation at a mean period of 6.1 ± 0.83 years (5.1–7.0 years) follow-up.

Conclusion

PBID is an effective surgical procedure in the long-term and can delay the need for liver transplantation in children with PFIC by reducing jaundice and pruritus.  相似文献   
89.
Introduction: The split‐hand phenomenon refers to preferential wasting of the thenar muscles with relative sparing of the hypothenar muscles in amyotrophic lateral sclerosis (ALS). Methods: We compared the split‐hand index (SI) calculated from the compound muscle action potential (CMAP; SICMAP) with that calculated from the motor unit number index (MUNIX; SIMUNIX). We performed MUNIX on the abductor policis brevis (APB), first dorsal interosseous (FDI), and abductor digiti minimi (ADM) muscles of 39 ALS patients and 40 age‐matched, healthy controls. SI is derived by multiplying the CMAP (or MUNIX) recorded over the APB and FDI and dividing by the CMAP (or MUNIX) recorded over the ADM. Results: Receiver‐operating characteristic curve analysis revealed good diagnostic accuracy for both indices, but better performance of SIMUNIX than SICMAP. Conclusion: SIMUNIX and SICMAP were useful in differentiating ALS patients from healthy controls. SIMUNIX appears to be a better electrophysiological marker than SICMAP for the split‐hand sign of ALS. Muscle Nerve 53 : 885–888, 2016  相似文献   
90.
Abstract Accessory tricuspid valve (TV) tissue is a rare congenital cardiac anomaly with varying clinical and hemodynamic features. We report a rare case of accessory TV tissue causing severe right ventricular outflow tract obstruction (RVOT) in a patient without associated cardiac anomaly. Surgical resection of the isolated accessory TV tissue resulted in complete relief of the RVOT without compromising TV function . (J Card Surg 2010;25:410‐411)  相似文献   
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