全文获取类型
收费全文 | 3930篇 |
免费 | 162篇 |
国内免费 | 36篇 |
专业分类
耳鼻咽喉 | 71篇 |
儿科学 | 109篇 |
妇产科学 | 218篇 |
基础医学 | 311篇 |
口腔科学 | 139篇 |
临床医学 | 317篇 |
内科学 | 885篇 |
皮肤病学 | 126篇 |
神经病学 | 222篇 |
特种医学 | 135篇 |
外科学 | 777篇 |
综合类 | 59篇 |
预防医学 | 127篇 |
眼科学 | 114篇 |
药学 | 193篇 |
中国医学 | 6篇 |
肿瘤学 | 319篇 |
出版年
2024年 | 3篇 |
2023年 | 27篇 |
2022年 | 56篇 |
2021年 | 70篇 |
2020年 | 46篇 |
2019年 | 72篇 |
2018年 | 111篇 |
2017年 | 70篇 |
2016年 | 118篇 |
2015年 | 126篇 |
2014年 | 153篇 |
2013年 | 206篇 |
2012年 | 295篇 |
2011年 | 321篇 |
2010年 | 149篇 |
2009年 | 129篇 |
2008年 | 277篇 |
2007年 | 338篇 |
2006年 | 300篇 |
2005年 | 311篇 |
2004年 | 244篇 |
2003年 | 195篇 |
2002年 | 158篇 |
2001年 | 89篇 |
2000年 | 73篇 |
1999年 | 62篇 |
1998年 | 11篇 |
1997年 | 13篇 |
1996年 | 11篇 |
1995年 | 13篇 |
1993年 | 6篇 |
1992年 | 17篇 |
1991年 | 18篇 |
1990年 | 13篇 |
1989年 | 9篇 |
1988年 | 7篇 |
1987年 | 2篇 |
1986年 | 2篇 |
1983年 | 1篇 |
1980年 | 1篇 |
1979年 | 1篇 |
1978年 | 2篇 |
1977年 | 2篇 |
排序方式: 共有4128条查询结果,搜索用时 0 毫秒
71.
Berkdemir Siverekli N Sahin O Senel S Hayta E Kaptanoglu E Elden H 《Rheumatology international》2012,32(8):2453-2457
The aim of this study was to evaluate the bone mineral density (BMD) in familial Mediterranean fever (FMF) and to search the effects of genetic factors, family history of FMF and types of clinical attacks on BMD. Forty-four attack-free patients with FMF and 36 healthy voluntary subjects were included in the study. BMD measurements of lumbar spine and left proximal femur were performed by dual energy X-ray absorptiometry (DEXA). There was no statistically significant difference between patient and control groups regarding median values of lumbar BMD (P?=?0.06), lumbar T (P?=?0.08) and Z (P?=?0.12) scores, femoral neck BMD (P?=?0.13), femoral T (P?=?0.22) and Z (P?=?0.16) scores and total femur BMD (P?=?0.14), T (P?=?0.19) and Z (P?=?0.27) scores. Patients with negative FMF family history had significantly lower femoral neck BMD (P?=?0.018), femoral neck T (P?=?0.009) and Z (P?=?0.01) scores and total femur BMD (P?=?0.033) than patients with positive FMF family history. There was no significant difference among the groups regarding mutation characteristic and types of attacks in lumbar BMD, T and Z scores, femoral neck BMD, T and Z scores and total femur BMD, T and Z scores (P?>?0.05). We found that the bone loss of patients with FMF is not different from that of the controls. The increased bone loss in the patients with negative family history for FMF should be further investigated with larger patient groups taking into consideration of the risk factors related to family history for osteoporosis. 相似文献
72.
73.
74.
Kırış A Karaman K Kırış G Sahin M Durmuş I Kaplan S Orem A Kutlu M Ayar A 《Echocardiography (Mount Kisco, N.Y.)》2012,29(8):914-922
Objectives: Left ventricular (LV) systolic synchrony, defined as simultaneous peak contractions of corresponding cardiac segments, is well documented to be impaired in hypertension but its effect on LV function is not clear. The aim of this study was to assess the impacts of LV systolic dyssynchrony on LV function in newly diagnosed hypertensives. Methods: Forty-eight newly diagnosed hypertensive patients and 33 controls were enrolled. All study population underwent a comprehensive echocardiographic evaluation including tissue synchrony imaging. The time to regional peak systolic tissue velocity (Ts) in LV by 12 segmental models was measured and two parameters of systolic dyssynchrony were computed. Results: Baseline demographic characteristics were similar in both study groups. Dyssynchrony parameters prolonged in newly diagnosed hypertensive patients compared to controls: the standard deviation (SD) of 12 LV segments Ts (40.2 ± 21 vs. 26.2 ± 13.4, P = 0.003); the maximal difference in Ts between any 2 of 12 LV segments (123.3 ± 61.5 vs. 79.8 ± 37.9, P = 0.001). In multivariable analysis, Ts-SD-12 was found to be an independent predictor for systolic function (β=-0.29, P = 0.008). But, both diastolic and global functions were not independently related to Ts-SD-12. Conclusion: LV synchronization is impaired in newly diagnosed hypertensive patients. LV dyssynchrony is one of the independent predictors of systolic function in hypertensive patients. 相似文献
75.
Yazar S Yaman O Demirtaş F Yalçin S Yücesoy M Sahin I 《Acta gastro-enterologica Belgica》2002,65(4):241-244
A 52 year-old male patient with idiopathic hepatic cirrhosis complaining of diarrhea and weakness was accepted to the gastroenterology clinic. In order to find out the causative etiologic agent of diarrhea, stool samples were examined by different methods and stained using modified Kinyoun's acid-fast stain. Following examination, approximately 9 microns diameter, acid-fast variable wrinkled spheres were seen and diagnosed as Cyclospora cayetanensis. Confirmation of the diagnosis was established by fluorescent microscope (380 to 420 nm excitation filter), which showed bright green to intense blue autofluorescent oocysts. It has been shown that, Cyclospora cayetanensis is a coccidian parasite mainly found in immunocompromised patients and that it may be the agent of prolonged diarrhea. Only three cyclosporiosis cases have been previously reported in our country; all three cases were AIDS patients. We report here a further case of Cyclospora cayetanensis infection in a patient with hepatic cirrhosis and we consider that this is the first case, which was reported in hepatic cirrhosis. 相似文献
76.
77.
The potential use of unmanned aircraft systems (drones) in mountain search and rescue operations 总被引:4,自引:0,他引:4
Yunus Karaca Mustafa Cicek Ozgur Tatli Aynur Sahin Sinan Pasli Muhammed Fatih Beser Suleyman Turedi 《The American journal of emergency medicine》2018,36(4):583-588
Objective
This study explores the potential use of drones in searching for and locating victims and of motorized transportation of search and rescue providers in a mountain environment using a simulation model.Methods
This prospective randomized simulation study was performed in order to compare two different search and rescue techniques in searching for an unconscious victim on snow-covered ground. In the control arm, the Classical Line Search Technique (CLT) was used, in which the search is performed on foot and the victim is reached on foot. In the intervention arm, the Drone-snowmobile Technique (DST) was used, the search being performed by drone and the victim reached by snowmobile. The primary outcome of the study was the comparison of the two search and rescue techniques in terms of first human contact time.Results
Twenty search and rescue operations were conducted in this study. Median time to arrival at the mannequin was 57.3 min for CLT, compared to 8.9 min for DST. The median value of the total searched area was 88,322.0 m2 for CLT and 228,613.0 m2 for DST. The median area searched per minute was 1489.6 m2 for CLT and 32,979.9 m2 for DST (p < 0.01 for all comparisons).Conclusions
In conclusion, a wider area can be searched faster by drone using DST compared to the classical technique, and the victim can be located faster and reached earlier with rescuers transported by snowmobile. 相似文献78.
Eroglu Didem Sahin Torgutalp Murat Baysal Serdar Colaklar Anil Sezer Serdar Yayla Mucteba Enes Uzun Caglar Turgay Tahsin Murat Kinikli Gulay Ates Askin 《Clinical rheumatology》2021,40(10):4127-4134
Clinical Rheumatology - To report the clinical characteristics of pulmonary artery involvement (PAI) in patients with Behçet’s syndrome (BS) and to define the predictors of relapses. We... 相似文献
79.
Uzuner Selcuk Durcan Gizem Sahin Sezgin Bahali Kayhan Barut Kenan Kilicoglu Ali Guven Adrovic Amra Bilgic Ayhan Kasapcopur Ozgur 《Clinical rheumatology》2021,40(12):5025-5032
Clinical Rheumatology - Having a child with a chronic illness is a source of stress for the whole family, especially the primary caregiver. The aim of this study was to evaluate the associations... 相似文献
80.
Zehra Narli Ozdemir Guldane Cengiz Seval Ugur Sahin Atilla Uslu Mehmet Gunduz Sinem Civriz Bozdag Selami Kocak Toprak Meltem Kurt Yuksel Pervin Topcuoglu Isinsu Kuzu Muhit Ozcan Gunhan Gurman Osman Ilhan 《Indian journal of hematology & blood transfusion》2021,37(1):67
PurposeBlastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and poor prognostic hematological malignancy. There is still no standard treatment established for BPDCN patients. We aim to summarize the main clinical, biological features and treatment of 9 BPDCN patients.MethodsNine patients with BPDCN who had been diagnosed between July 2008 and December 2018 in Ankara University School of Medicine, were retrospectively evaluated.ResultsAll patients (n = 9) were male, median age was 64 (21–80). Five patients (55.6%) had bone marrow infiltration, 5 patients (55.6%) cutaneous lesions, 6 patients (66.7%) lymph node involvement, 2 patients (22.2%) central nervous system involvement and 2 patients (22.2%) spleen involvement at time of diagnosis. Complex karyotype was observed in 2 patients. CHOP was given to 5 patients (55.6%), hyper-CVAD to 2 patients (22.2%), fludarabine, cyclophosphamide and mitoxantrone to 1 patient (11.1%) and cyclophosphamide, etoposide, methylprednisolone to 1 patient (11.1%) as first line chemotherapy. Four patients (44.4%) underwent allogeneic hematopoietic stem cell transplantation (AHSCT) in complete remission (CR) 1. Venetoclax was given to a transplant ineligible patient who had skin and lymph node involvement, with the off-label use. The median follow-up time was 15.9 months (3–48.6 months). Estimated median overall survival was 15.9 + 1.6 (95% CI 12.7–19.1) months.ConclusionIntensive induction therapies followed by AHSCT in CR seems to be best approaches for patients with BPDCN. Thus, more effective treatment strategies particularly targeted therapies should be warranted to improve the survival of patients with this rare disease. 相似文献