全文获取类型
收费全文 | 2477篇 |
免费 | 95篇 |
国内免费 | 30篇 |
专业分类
耳鼻咽喉 | 3篇 |
儿科学 | 98篇 |
妇产科学 | 22篇 |
基础医学 | 433篇 |
口腔科学 | 83篇 |
临床医学 | 252篇 |
内科学 | 538篇 |
皮肤病学 | 123篇 |
神经病学 | 48篇 |
特种医学 | 304篇 |
外科学 | 240篇 |
综合类 | 49篇 |
预防医学 | 88篇 |
眼科学 | 25篇 |
药学 | 222篇 |
中国医学 | 1篇 |
肿瘤学 | 73篇 |
出版年
2015年 | 26篇 |
2014年 | 24篇 |
2013年 | 85篇 |
2012年 | 29篇 |
2010年 | 49篇 |
2009年 | 38篇 |
2008年 | 35篇 |
2007年 | 53篇 |
2006年 | 59篇 |
2005年 | 41篇 |
2004年 | 36篇 |
2003年 | 36篇 |
2002年 | 29篇 |
2001年 | 41篇 |
2000年 | 33篇 |
1999年 | 45篇 |
1998年 | 85篇 |
1997年 | 97篇 |
1996年 | 107篇 |
1995年 | 74篇 |
1994年 | 74篇 |
1993年 | 76篇 |
1992年 | 49篇 |
1991年 | 39篇 |
1990年 | 47篇 |
1989年 | 70篇 |
1988年 | 65篇 |
1987年 | 58篇 |
1986年 | 60篇 |
1985年 | 46篇 |
1984年 | 60篇 |
1983年 | 33篇 |
1982年 | 33篇 |
1981年 | 40篇 |
1980年 | 49篇 |
1979年 | 27篇 |
1978年 | 30篇 |
1977年 | 38篇 |
1976年 | 41篇 |
1975年 | 39篇 |
1972年 | 27篇 |
1971年 | 25篇 |
1970年 | 26篇 |
1969年 | 23篇 |
1965年 | 53篇 |
1964年 | 50篇 |
1963年 | 47篇 |
1962年 | 42篇 |
1961年 | 40篇 |
1960年 | 65篇 |
排序方式: 共有2602条查询结果,搜索用时 15 毫秒
121.
CHARLES R. CANNAN M.B. Ch.B. STUART T. HIGANO M.D. DAVID R. HOLMES JR. M.D. KIRK N. GARRATT M.D. AMIR LERMAN M.D. 《Journal of interventional cardiology》1996,9(2):153-161
Coronary artery disease is a progressive and diffuse process. The focus in the past decade was on the late stage of coronary atherosclerosis, with efforts being devoted to the development of thrombolytic drugs and sophisticated interventional devices. However, in spite of the success in decreasing morbidity and mortality from coronary atherosclerosis, the disease process continues. Early diagnosis and treatment of patients with nonobstructive coronary artery disease, may prevent the development of unstable angina and myocardial infarction. It has become apparent that the endothelium is the primary target and/or participant in the early stages of coronary atherosclerosis. The endothelium is as an active paracrine organ capable of regulating coronary vascular tone as well as the atherosclerotic and restenosis process by releasing vasorelaxing factors with antiproliferative activity and vasoconstricting and growth factors. During the evolution of coronary atherosclerosis endothelial dysfunction occurs, which is characterized by attenuated release and activity of endothelium derived vasorelaxing factors and enhanced release of vasoconstricting factors. The goal of cardiology is to develop diagnostic methods and treatment for these patients who present to us with cardiac symptoms and nonobstructive coronary artery disease. This article will review the current knowledge of endothelial function as it applies to coronary circulation and describe a clinical approach to the patient with suspected coronary disease and a normal coronary angiogram. (J Interven Cardiol 1996;9:153–161) 相似文献
122.
We report our experience with nasal mask ventilation in children and adolescents with type II respiratory failure admitted to the paediatric intensive care unit (PICU) over an 18-month period. Seven patients were treated with nasal mask ventilation during part of their PICU stay. All showed significant improvement in arterial pH, PaCO2, and PaO2/FiO2 from presentation to discharge, although at discharge PaCO2 and PaO2/FiO2 fell outside of the normal range. Complications occurred in four patients. When compared to 11 patients with type II respiratory failure not treated with nasal mask ventilation, the nasal mask ventilation group had a similar PICU length of stay and incidence of complications. We conclude that nasal mask ventilation may be useful in maintaining near normal alveolar ventilation in selected children with type II respiratory failure and that a prospective study of this technique is indicated. 相似文献
123.
MOLLER M.; THAYSSEN P.; ALSTRUP P.; HAGHFELT T.; ANDERSEN P. E. JR. 《European heart journal》1983,4(1):26-30
The effect of coronary artery bypass surgery (CAB) on ventriculararrhythmias (VA) was studied in a prospective investigationinvolving 32 patients (mean age 54 years) who underwent CABbecause of severe stable angina pectoris. Prior to CAB as wellas 12 months later each patient was subjected to the followinginvestigational programme: resting ECG, exercise ECG, 24-h ECG,selective coronary arteriography, ventriculography and cardiaccatheterization. Exercise ECG showed VA in only three patients.The prevalence of VA during 24-h ECG was 56 and 66% on the twooccasions (NS), while complicated VA (multiform, repetitive,R on T) was seen in 18 and 28%, respectively (NS). The persistence(number of 6-h periods showing VA) was 33 and 47% with regardto any VA (P<0.05), while complicated VA occurred in 13 and15% of the 6-h periods (NS). Except for an increase in dp/dtmax/Pat the postoperative measurement (P<0.05), no significantchange in the performance of the left ventricle was seen afterCAB though the graft patency was 77%. It is concluded that inpatients with medically intractable stable anginapectoris, CAB does not effect the occurrence of VA to any greatextent probably because left ventricular function isunchanged one year after as compared with that prior to CAB. 相似文献
124.
Computed tomography of the pancreas 总被引:2,自引:0,他引:2
125.
SMETHURST P. W. R.; FORREST W. H. JR.; HAYDEN J. 《British journal of anaesthesia》1971,43(12):1129-1135
The respiratory depressant effects of a potent analgesic (GPA2087) were compared with morphine in a randomized double-blindcross-over study in human volunteers. Using a rebreathing technique,carbon dioxide response curves were plotted automatically witha special-purpose analog computer. The respiratory depressantrelative potency of GPA 2087 to morphine was found to be 1.21with lower and upper 95 per cent confidence limits of 0.88 and2.04. Our best estimate based on the displacement of the respiratoryresponse curve is that GPA 2087 8 mg is the equivalent of morphine10 mg in our population of volunteers.
*Geigy Pharmaceuticals, Ardsley, New York, U.S.A.
*Present address: Salisbury General Infirmary, Odstock Branch,Salisbury, Wiltshire, England. 相似文献
126.
127.
BENIGN ORGASMIC CEPHALGIA 总被引:3,自引:0,他引:3
GEORGE W. PAULSON M.D. Neurologist HAROLD L. KLAWANS JR. M.D. Associate Professor 《Headache》1974,13(4):181-187
128.
129.
MIELKE C. H. JR.; KANESHIRO M. M.; MAHER I. A.; WEINER J. M.; RAPAPORT S. I. 《Blood》1969,34(2):204-215
A standardized, reproducible Ivy bleeding time technic has been describedwhich permits one to obtain accurate bleeding time data in man. Thetechnic was used to standardize an aspirin tolerance test in which 60 normal males had a control bleeding time; were given, on a double blind basis,either placebo or 1 Gm. of aspirin, and had a second bleeding time 2 hourslater. The control values were: mean, 5 min.; mean ± 2 st. dev., 2 min.,30 sec. to 10 min. The values after placebo were: mean, 5 min., 30 sec.;mean ± 2 st. dev., 2 min., 30 sec. to 11 min. The values after aspirin were:mean, 9 min., 30 sec.; mean ± 2 st. dev., 4 min. to 21 min. The differencebetween the mean bleeding time after placebo and after aspirin was highlysignificant (p < 0.001). The distribution of the bleeding times after aspirinsuggested that normal subjects do not respond to aspirin as a single population. The degree of prolongation of the bleeding time and the large size ofthe drops of blood observed in some subjects suggested to us that smallamounts of aspirin may exert a significant effect upon hemostasis in normalindividuals. Submitted on January 10, 1969 Accepted on April 23, 1969 相似文献
130.