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51.
Fabio Salvatore Macaluso Marco Ventimiglia Walter Fries Anna Viola Aldo Sitibondo Maria Cappello Barbara Scrivo Anita Busacca Antonino Carlo Privitera Salvatore Camilleri Serena Garufi Roberto Di Mitri Filippo Mocciaro Nunzio Belluardo Emiliano Giangreco Carmelo Bertolami Sara Renna Rosalba Orlando Giulia Rizzuto Mario Cottone Ambrogio Orlando 《Journal of gastroenterology and hepatology》2021,36(1):105-111
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In vitro development of engineered muscle using a scaffold based on the pressure‐activated microsyringe (PAM) technique
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![点击此处可从《Journal of tissue engineering and regenerative medicine》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Daniele Cei Adriana Malena Carmelo de Maria Emanuele Loro Federica Sandri Giulia del Moro Sara Bettio Lodovica Vergani Giovanni Vozzi 《Journal of tissue engineering and regenerative medicine》2017,11(1):138-152
The development of new human skeletal muscle tissue is an alternative approach to the replacement of tissue after severe damage, for example in the case of traumatic injury, where surgical reconstruction is often needed following major loss of natural tissue. Treatment to date has involved the transfer of muscle tissue from other sites, resulting in a functional loss and volume deficiency of donor sites. Approaches that seek to eliminate these problems include the relatively new solution of skeletal muscle engineering. Here there are two main components to consider: (a) the cells with their regenerative potential; and (b) the polymeric structure onto which cells are seeded and where they must perform their activities. In this paper we describe well‐defined two‐ and three‐dimensional polymeric structures able to drive the myoblast process of adhesion, proliferation and differentiation. We examine a series of polymers and protein adhesions with which to functionalize the structures, and cell‐seeding methods, with a view to defining the optimal protocol for engineering skeletal muscle tissue. All polymer samples were tested for their mechanical and biological properties, to support the validity of our results in the real context of muscle tissue engineering. Copyright © 2014 John Wiley & Sons, Ltd. 相似文献
53.
Recurrent NAB2–STAT6 gene fusions and oestrogen receptor‐α expression in pulmonary adenofibromas
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![点击此处可从《Histopathology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Nicola Fusco Elena Guerini‐Rocco Claudia Augello Andrea Terrasi Giulia Ercoli Caterina Fumagalli Davide Vacirca Paola Braidotti Antonina Parafioriti Marta Jaconi Letterio Runza Vijayalakshmi Ananthanarayanan Fabio Pagni Silvano Bosari Massimo Barberis Stefano Ferrero 《Histopathology》2017,70(6):906-917
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Manuel Menzocchi Giulia Paoletti Alexa Huber Giancarlo Carli Francesca I. Cavallaro Diego Manzoni 《The International journal of clinical and experimental hypnosis》2013,61(1):122-135
In highly hypnotizable individuals (highs), postural control is more independent of sensory information than in low hypnotizable subjects (lows). The aim of the study was to find out whether locomotion is also less affected in highs than in lows by visual suppression and changes in the neck proprioceptive input. Eighteen highs and 20 lows were asked to walk straight ahead, blindfolded, in basal conditions (face forward), during real and imagined right/left head rotation and mental computation. Highs detected deviations from the straight trajectory better than lows. Their walking direction was more straight during basal conditions and less influenced than the lows' one by mental computation and real/imagined rotation of the head. The results confirm highs' lower dependence on sensory inputs, although this cannot be definitely attributed to a better internal representation of space or to higher behavioral automaticity. 相似文献
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Giuseppe Fanetti Giulia Marvaso Delia Ciardo Annaisabel Rese Rosalinda Ricotti Elena Rondi Stefania Comi Federica Cattani Dario Zerini Cristiana Fodor Ottavio de Cobelli Roberto Orecchia Barbara A. Jereczek-Fossa 《Medical oncology (Northwood, London, England)》2018,35(5):75
To evaluate outcome in patients treated with stereotactic body radiotherapy (SBRT) on bone oligometastases from castration-sensitive prostate cancer after primary treatment. We retrospectively collected data of patients with less than five lesions at time of SBRT and hormone-naïve disease at the first extra-regional localization, treated between 03/2012 and 11/2016. Prostate-specific antigen (PSA) was measured every 3 months after SBRT. Imaging was performed in case of progression. Survival analysis was performed with Kaplan–Meier (log-rank test) approach. Fifty-five patients were treated on 77 bone oligometastases. Median age, initial PSA and pre-SBRT PSA were 72 years, 9.12 and 3.5 ng/mL, respectively. Twenty-five patients (45%) received SBRT alone while the remaining 30 patients (55%) received concomitant ADT. Median follow-up was 24.6 months (range 3.0–67.2 months). No acute or late toxicity of grade?>?1 was reported. Clinical progression was observed in 38 (69%) patients. 1-year biochemical progression-free survival (b-PFS), clinical progression-free survival (c-PFS), prostate-specific survival (PCSS) and local control (LC) rates were 51, 56, 100 and 83%, respectively. Comparing patients treated with SBRT alone and with concomitant ADT, no significant differences were found for those outcomes. SBRT is safe and allows high 1-year LC rate (83%) with low toxicity profile. No significant improvement in outcomes was registered with the addition of ADT to SBRT. 相似文献
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