全文获取类型
收费全文 | 10122篇 |
免费 | 544篇 |
国内免费 | 78篇 |
专业分类
耳鼻咽喉 | 116篇 |
儿科学 | 226篇 |
妇产科学 | 184篇 |
基础医学 | 1305篇 |
口腔科学 | 240篇 |
临床医学 | 1041篇 |
内科学 | 2430篇 |
皮肤病学 | 112篇 |
神经病学 | 1164篇 |
特种医学 | 352篇 |
外科学 | 1658篇 |
综合类 | 14篇 |
预防医学 | 290篇 |
眼科学 | 105篇 |
药学 | 610篇 |
中国医学 | 12篇 |
肿瘤学 | 885篇 |
出版年
2024年 | 10篇 |
2023年 | 54篇 |
2022年 | 151篇 |
2021年 | 217篇 |
2020年 | 133篇 |
2019年 | 184篇 |
2018年 | 253篇 |
2017年 | 211篇 |
2016年 | 252篇 |
2015年 | 237篇 |
2014年 | 361篇 |
2013年 | 496篇 |
2012年 | 779篇 |
2011年 | 712篇 |
2010年 | 401篇 |
2009年 | 387篇 |
2008年 | 673篇 |
2007年 | 641篇 |
2006年 | 683篇 |
2005年 | 660篇 |
2004年 | 688篇 |
2003年 | 599篇 |
2002年 | 510篇 |
2001年 | 101篇 |
2000年 | 76篇 |
1999年 | 86篇 |
1998年 | 116篇 |
1997年 | 86篇 |
1996年 | 93篇 |
1995年 | 81篇 |
1994年 | 69篇 |
1993年 | 73篇 |
1992年 | 66篇 |
1991年 | 66篇 |
1990年 | 48篇 |
1989年 | 53篇 |
1988年 | 39篇 |
1987年 | 36篇 |
1986年 | 39篇 |
1985年 | 31篇 |
1984年 | 37篇 |
1983年 | 29篇 |
1982年 | 37篇 |
1981年 | 33篇 |
1980年 | 28篇 |
1979年 | 16篇 |
1978年 | 16篇 |
1977年 | 12篇 |
1975年 | 10篇 |
1972年 | 9篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
991.
目的 评价二次冠状动脉旁路移植术的临床疗效.方法 51例病人(占医院同期进行冠状动脉旁路移植术病人的2.5%)进行二次冠状动脉旁路移植术,距首次手术(15.1±5.8)年.10例采用非体外循环冠状动脉旁路移植术(OPCABG),41例采用体外循环冠状动脉旁路移植术(CABG).正中切口43例,左胸侧切口8例.结果 3例行CABG病人手术后呼吸衰竭,需呼吸机辅助.所有病人住ICU(2.2±0.7)天,住院(9.2±2.4)天.术后死亡2例(3.9%),采用OPCABG和CABG者各1例,死亡原因分别为急性心肌梗死、低心排血量综合征和呼吸功能衰竭、重症肺炎.完全再血管化44例,其中行OPCABG者6例,CABG者38例.部分再血管化7例,行OPCABG者4例,CABG者3例.结论 CABG和OPCABG行二次冠状动脉旁路移植术均安全,疗效满意,能达到完全再血管化的目的. 相似文献
992.
Carmignani L Morabito A Gadda F Bozzini G Rocco F Colpi GM 《The Journal of urology》2005,174(3):1035-1038
993.
Peter B. Marschik Walter E. Kaufmann Jeff Sigafoos Thomas Wolin Dajie Zhang Katrin D. Bartl-Pokorny Giorgio Pini Michele Zappella Helen Tager-Flusberg Christa Einspieler Michael V. Johnston 《Research in developmental disabilities》2013,34(4):1236-1239
We delineated the achievement of early speech-language milestones in 15 young children with Rett syndrome (MECP2 positive) in the first two years of life using retrospective video analysis. By contrast to the commonly accepted concept that these children are normal in the pre-regression period, we found markedly atypical development of speech-language capacities, suggesting a paradigm shift in the pathogenesis of Rett syndrome and a possible approach to its early detection. 相似文献
994.
Successful conception and pregnancy in p‐ANCA‐associated vasculitis in course of treatment with immunosuppressive drugs and renal replacement therapy 下载免费PDF全文
995.
Paola Ballerini Saro Oriana Piergiorgio Duca Antonia Martinetti Elisabetta Venturelli Leonardo Ferrari Stella Dolci Giorgio Secreto 《Breast cancer research and treatment》1993,26(1):1-6
Summary We investigated the role of urinary testosterone levels as a marker of risk of recurrent disease in 113 operable breast cancer patients (70 premenopausal, 43 postmenopausal). Twenty-four-hour urine collections for testosterone measurement were obtained before surgical treatment, between 20–40 days thereafter, and then every 6 months for 5 years. The cutoff values to separate high testosterone (A+) from normal testosterone (A–) were 8.0µg/24h in premenopause and 4.9µg/24h in postmenopause. Urinary testosterone levels were considered high when they exceeded the cutoff value in at least 2 of the first 3 measurements (pretreatment, post-treatment, 6 months) of each patient. According to the aforementioned criterion, 33 patients (29.2%) had high testosterone levels, which were associated to axillary node involvement in 16 patients. Thirteen of the latter relapsed during the 5-year follow-up period (5/7 in premenopause, 8/9 in postmenopause). Relapse-free survival (RFS) curves were drawn only for node-positive patients owning to the small number of recurrences observed in the node-negative group. In premenopausal node-positive patients, RFS was significantly different for patients presenting high and normal urinary testosterone levels (77% vs 28%, respectively; logrank test, p< 0.006). In postmenopausal node-positive patients, RFS was also different between the two groups (54% vs 11% in high and normal excretors, respectively) but the difference was not statistically significant. The present findings suggest that urinary testosterone is a prognostic indicator of early breast cancer recurrence in node-positive patients. 相似文献
996.
Michele Giuliani MD DDSa Carlo Lajolo MDa Giorgio Deli MD DDSb Caterina Silveri MD 《Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics》2001,92(6):670-674
Sensory disturbances such as anesthesia, hypoesthesia, hyperesthesia, and paresthesia may be present in the oral cavity, stemming from many local and systemic factors. Paresthesia of the inferior alveolar nerve is quite rare because of the unique anatomy of this nerve. Among other effects, periapical lesions can damage the nerve, resulting in paresthesia of its innervated area. Only a few cases of paresthesia caused by these lesions are reported in the literature. In this report we present a case of paresthesia of the right inferior alveolar nerve; discuss the anatomy, pathobiology, and etiology; and suggest that a periapical lesion affecting the lower right second molar (No. 31) may have been the cause. The routine x-rays (intraoral and panorex) and the axial and cross-sectional tomographs of the mandible by means of computed tomography contribute to making this case a good example of nerve injury. 相似文献
997.
998.
Longitudinal Evaluation of Vitamin D Status in Healthy Subjects from Southern Italy: Seasonal and Gender Differences 总被引:4,自引:0,他引:4
V. Carnevale S. Modoni M. Pileri A. Di Giorgio I. Chiodini S. Minisola R. Vieth A. Scillitani 《Osteoporosis international》2001,12(12):1026-1030
Vitamin D status is currently considered among the relevant determinants of skeletal integrity. Since vitamin D levels present
seasonal variations, we longitudinally studied young healthy men and women in order to investigate the related physiologic
modifications of both calcium homeostasis and bone remodeling. Thirty-two men (mean age 39.4 ± 7.8 years) and 58 premenopausal
women (aged 36.9 ± 6.4 years) from southern Italy were studied. In all subjects the following parameters were measured both
in winter and in summer: serum calcium, phosphorus, creatinine, total alkaline phosphatase activity, 25-hydroxyvitamin D (25OHD),
parathyroid hormone (PTH), osteocalcin (BGP), together with urinary calcium (Ca/Cr), total pyridinoline (Pyr/Cr) and deoxypyridinoline
(d-Pyr/Cr), corrected for creatinine excretion. In both sexes 25OHD levels were significantly higher in summer, while PTH
values were lower, than in winter. The prevalence of hypovitaminosis D, defined by concentrations of 25OHD lower than 30 nmol/l,
was 17.8% in winter and 2.2% in summer in the whole sample, while it was 27.8% and 3.4%, respectively, among female subjects.
Indeed male subjects did not display hypovitaminosis D, having throughout the year significantly higher calcium and 25OHD
levels together with lower PTH values, than the women. Moreover, alkaline phosphatase total activity was more elevated in
men both in winter and in summer. In women, during winter, bone remodeling markers levels were higher while urinary calcium
levels were lower than in summer. In the whole sample serum 25OHD correlated positively with serum calcium and inversely with
PTH. The seasonal percentage variations in PTH were inversely correlated with those of Ca/Cr. Our results show a relatively
high prevalence of subclinical vitamin D deficiency among young healthy women from southern Italy. Significant gender-specific
differences have been demonstrated in both calcium homeostasis and skeletal remodeling indexes; the seasonal fluctuations
in the vitamin D–PTH axis are accompanied by cyclical variations of bone turnover rate, which were more pronounced in women.
Received: 11 January 2001 / Accepted: 6 July 2001 相似文献
999.
Identification of pathologically favorable disease in intermediate‐risk prostate cancer patients: Implications for active surveillance candidates selection 下载免费PDF全文
1000.
Toffoli G Vattovani O Cecchini P Pastori G Rinaldi G Ravalico G 《Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde》2002,216(3):159-163
OBJECTIVE: To establish a correlation between the retinal nerve fiber layer (RNFL) thickness measured by a scanning laser polarimeter (GDx) and the pattern electroretinogram (p-ERG) amplitudes in a heterogeneous population sample composed of normal subjects, ocular hypertensive and glaucomatous patients. METHODS: 112 subjects were considered: 40 glaucomatous patients, 39 ocular hypertensive and 33 normal subjects. All were examined with the GDx, and the RNFL thickness was measured. A transient p-ERG was then recorded. RESULTS: A statistically significant correlation was observed between the RNFL thickness and the p-ERG amplitudes (p < 0.001) by means of linear regression analysis. CONCLUSION: We observed a strict correlation between the measurements of the RNFL thickness obtained with the GDx and the amplitude of the p-ERG signal. These techniques represent additional objective tools to detect an early glaucomatous damage. 相似文献