全文获取类型
收费全文 | 7174篇 |
免费 | 477篇 |
国内免费 | 25篇 |
专业分类
耳鼻咽喉 | 125篇 |
儿科学 | 197篇 |
妇产科学 | 183篇 |
基础医学 | 956篇 |
口腔科学 | 151篇 |
临床医学 | 497篇 |
内科学 | 1827篇 |
皮肤病学 | 226篇 |
神经病学 | 580篇 |
特种医学 | 229篇 |
外科学 | 1110篇 |
综合类 | 38篇 |
一般理论 | 1篇 |
预防医学 | 616篇 |
眼科学 | 108篇 |
药学 | 370篇 |
中国医学 | 33篇 |
肿瘤学 | 429篇 |
出版年
2023年 | 41篇 |
2022年 | 105篇 |
2021年 | 188篇 |
2020年 | 101篇 |
2019年 | 199篇 |
2018年 | 238篇 |
2017年 | 167篇 |
2016年 | 185篇 |
2015年 | 191篇 |
2014年 | 279篇 |
2013年 | 367篇 |
2012年 | 456篇 |
2011年 | 491篇 |
2010年 | 311篇 |
2009年 | 306篇 |
2008年 | 424篇 |
2007年 | 432篇 |
2006年 | 430篇 |
2005年 | 425篇 |
2004年 | 348篇 |
2003年 | 365篇 |
2002年 | 304篇 |
2001年 | 144篇 |
2000年 | 183篇 |
1999年 | 171篇 |
1998年 | 52篇 |
1997年 | 54篇 |
1996年 | 42篇 |
1995年 | 29篇 |
1994年 | 24篇 |
1993年 | 31篇 |
1992年 | 74篇 |
1991年 | 59篇 |
1990年 | 73篇 |
1989年 | 54篇 |
1988年 | 39篇 |
1987年 | 43篇 |
1986年 | 41篇 |
1985年 | 38篇 |
1984年 | 27篇 |
1983年 | 19篇 |
1982年 | 12篇 |
1981年 | 9篇 |
1980年 | 9篇 |
1979年 | 8篇 |
1978年 | 10篇 |
1977年 | 8篇 |
1976年 | 8篇 |
1975年 | 10篇 |
1971年 | 13篇 |
排序方式: 共有7676条查询结果,搜索用时 15 毫秒
71.
72.
73.
74.
75.
76.
Alfonso Gil R Hurtado Navarro I Espacio Casanovas A Santos Rubio G Tomás Dols S 《Gaceta sanitaria / S.E.S.P.A.S》1999,13(1):16-21
OBJECTIVE: The purpose of this study was to describe the sociodemographic and serologic profiles in a first time consultant population at the Information and AIDS Prevention Center of Valencia (Spain). In addition, the HIV infection risk factors were analyzed. METHOD: A cross-sectional study was performed on 1,573 persons who consulted during the year 1995. Sociodemographic and infection risk practices data were recorded and serologic information about HIV, HBV and HCV infection were obtained. Exact binomial method with a 95% interval confidence was used to calculate infection prevalence and the chi square test to make comparisons between qualitative variables. RESULTS: Sex distribution was 66,1% males and 31,9% females; mean age was 29,01 (SD: 9.2) years. Sexual intercourse without condom (25.2%) and parenteral drug abusers (22.6%) were the more frequent risk groups seeking consultation about HIV infection. Global HIV infection prevalence was 12.7% (95% CI= 11,2-14,5%). Among HIV seropositive patients, sexual transmission accounted for 30.8% of cases, of which 69.4% were heterosexual relations. The HIV infection prevalence for different risk groups were the following: parenteral drug abusers 36.8% (95% CI= 31,7-42%), heterosexual intercourse with an HIV-infected partner 24.1% (95% CI= 17,1-32,2%) and homosexual intercourse between men 9,5% (95% CI= 5,8-14,5%). HCV antibody prevalence for parenteral drug abusers was 81.2% (95% CI= 76,7-85,1%). Risk practices with a statistically significant association with HIV infection were: being an injecting drug abuser, as well as having an HIV infected and/or a injecting drug abuser partner. CONCLUSIONS: Drug parenteral abusers are still the target population for prevention programs. Data suggest that prevention and sexual education programs must continue. The main effort should be focused on the young population and on sexual partners of injecting drug abusers and/or HIV seropositive partners. 相似文献
77.
Cosín-Aguilar J Marrugat J Sanz G Massó J Gil M Vargas R Pérez-Casar F Simarro E De Armas D García-García J Azpitarte J Diago JL Rodrigo-Trallero G Lekuona I Domingo E Marin-Huerta E 《Journal of cardiovascular pharmacology》1999,33(5):733-740
A randomized open-label clinical trial was conducted to determine whether mortality, readmission, or quality of life differed between heart failure patients managed with captopril plus diuretics and those with digoxin plus diuretics. A total of 345 heart failure patients in New York Heart Association functional classes 2 and 3 without atrial fibrillation, dyspnea of bronchopulmonary origin, or hypertension not controlled with diuretics was randomized for digoxin (n = 175) or captopril (n = 170) treatment and followed up for a median of 4.5 years. Socioeconomic, demographic, electrocardiographic, echocardiographic, spirometric, and chest radiograph data were obtained at the initial examination. In a random sample of half the patients, ergometric, echocardiographic, and Holter records were obtained at entry and at 3 and 18 months. Patients were followed up for > or = 3 years. The end points were mortality, hospitalization for cardiac events, deterioration in quality of life, worsening of functional class, and need for digoxin or captopril in the captopril and digoxin groups, respectively. The trial had to be terminated prematurely owing to the difficulty in finding candidates free of angiotensin-converting enzyme (ACE)-inhibitor treatment. Baseline patient characteristics were similar in both groups. From the clinical point of view, only the 48-month mortality was relevantly lower (20.9 vs. 31.9%, respectively) among patients treated with captopril than that in those receiving digoxin (log rank test, p = 0.07). No statistically or clinically relevant differences were found in other end points or adverse effects. The results suggest but do not confirm the hypothesis that captopril treatment in mild to moderate heart failure might provide better long-term survival than digoxin. 相似文献
78.
The GU-MACH study: the effect of 1-week omeprazole triple therapy on Helicobacter pylori infection in patients with gastric ulcer 总被引:5,自引:0,他引:5
P. Malfertheiner E. Bayerdörffer U. Diete J. Gil T. Lind P. Misiuna C. O''Morain P. Sipponen R. C. Spiller J. Stasiewicz H.-C. Treichel L. Ujszászy P. Unge S. J. O. Veldhuyzen van Zanten & L. Zeijlon 《Alimentary pharmacology & therapeutics》1999,13(6):703-712
AIMS: To study the efficacy of omeprazole triple therapy in the eradication of Helicobacter pylori in patients with active gastric ulcer, and to assess healing and relapse of gastric ulcer. METHODS: A double-blind, randomized study was carried out in 18 centres in Germany, Hungary and Poland. Patients (n = 160) with gastric ulcer and a positive H. pylori screening test were randomized to a 7-day twice daily treatment with omeprazole 20 mg, clarithromycin 500 mg and amoxycillin 1000 mg (OAC) or omeprazole 20 mg, clarithromycin 250 mg and metronidazole 400 mg (OMC), or with omeprazole 20 mg once daily (O). After completion of this 1-week treatment, patients were treated with omeprazole until healing (maximum 12 weeks), and followed for 6 months. H. pylori was assessed by urea breath test (UBT) and histology. RESULTS: Eradication rates ITT were OAC 79% (95% CI: 65-90%), OMC 86% (95% CI: 73-94%) and O 4% (95% CI: 0-14%). Eradication rates PP were OAC 83% (95% CI: 68-93%), OMC 93% (95% CI: 80-98%) and O 3% (95% CI: 0-13%). Gastric ulcer relapses occurred in 5, 0 and 11 patients in the groups, respectively. CONCLUSIONS: The results from the study demonstrate that OMC and OAC 1-week regimens are safe and effective for eradication of H. pylori in gastric ulcer patients, and that ulcer relapse is infrequent after successful eradication. 相似文献
79.
Prof. Dr. J. Simões da Fonseca M. Teresa Gil M. Luisa Figueira J. Guerreiro Barata Fernando Pego M. Fernanda Pacheco 《European archives of psychiatry and clinical neuroscience》1978,225(1):31-53
Summary The authors studied the behavior of normal subjects and paranoid schizophrenic patients in a simple problem-solving situation. The schizophrenics were divided into two sample groups, one of individuals under treatment and the other of individuals not under treatment.The learning process involved in this problem-solving situation is very similar to an instrumental conditioning, and can be understood by means of the following assumptions: (1) the subjects use decision functions in reacting to the stimuli, although they may be not fully aware of this; (2) learning is the result of successive transformations of these decisions in the course of time; (3) the changes have specific probabilities and are related to (a) those responses which are made to the latest stimuli, and (b) a differential probability for decision functions which were effective, or only interrupted painful reinforcement, or were completely ineffective.In schizophrenics further factors of importance were (1) an inertia factor and (2) the rigidly continued use of unsuccessful or only partially successful decision criteria.The authors used a systems theory based on Galois field theory and a calculus of operators specifying three groups of subjects. A computer program based on these hypotheses was tested in a simulation experiment.The statistical evaluation of the results showed a congruence between the theoretical approach and the experimental data.This work was carried out with financial support from the Institute de Alta Cultura, Lisbon, between 1970 and 1974 相似文献
80.
Rahmani R Gil P Martin M Durand A Barbet J Cano JP 《Journal of pharmaceutical and biomedical analysis》1983,1(3):301-309
The response of tumours to adriamycin, and the cardiotoxicity of the drug, may be related to its pharmacokinetics and plasma levels. Rapid and sensitive methods of adriamycin determination in plasma and urine samples are thus needed. A comparative study shows that high-performance liquid chromatography with fluorimetric detection is a reliable and specific method, but it is relatively slow and sometimes lacks sensitivity. A commercially-available radioimmunoassay kit is convenient, but there is a cross reaction with the major metabolise adriamycinol and unless the assay is combined with an extraction step, it gives erroneously high results. 相似文献