全文获取类型
收费全文 | 4264篇 |
免费 | 231篇 |
国内免费 | 53篇 |
专业分类
耳鼻咽喉 | 45篇 |
儿科学 | 92篇 |
妇产科学 | 82篇 |
基础医学 | 449篇 |
口腔科学 | 116篇 |
临床医学 | 310篇 |
内科学 | 1015篇 |
皮肤病学 | 58篇 |
神经病学 | 463篇 |
特种医学 | 163篇 |
外科学 | 965篇 |
综合类 | 5篇 |
预防医学 | 112篇 |
眼科学 | 107篇 |
药学 | 180篇 |
中国医学 | 4篇 |
肿瘤学 | 382篇 |
出版年
2024年 | 6篇 |
2023年 | 41篇 |
2022年 | 111篇 |
2021年 | 197篇 |
2020年 | 107篇 |
2019年 | 121篇 |
2018年 | 151篇 |
2017年 | 101篇 |
2016年 | 137篇 |
2015年 | 156篇 |
2014年 | 193篇 |
2013年 | 257篇 |
2012年 | 334篇 |
2011年 | 347篇 |
2010年 | 196篇 |
2009年 | 187篇 |
2008年 | 225篇 |
2007年 | 232篇 |
2006年 | 221篇 |
2005年 | 180篇 |
2004年 | 191篇 |
2003年 | 168篇 |
2002年 | 171篇 |
2001年 | 78篇 |
2000年 | 43篇 |
1999年 | 45篇 |
1998年 | 29篇 |
1997年 | 23篇 |
1996年 | 15篇 |
1995年 | 18篇 |
1994年 | 11篇 |
1993年 | 16篇 |
1992年 | 19篇 |
1991年 | 21篇 |
1990年 | 29篇 |
1989年 | 11篇 |
1988年 | 13篇 |
1987年 | 12篇 |
1986年 | 11篇 |
1985年 | 19篇 |
1984年 | 12篇 |
1983年 | 10篇 |
1982年 | 10篇 |
1981年 | 9篇 |
1979年 | 6篇 |
1978年 | 5篇 |
1971年 | 5篇 |
1969年 | 9篇 |
1968年 | 6篇 |
1966年 | 7篇 |
排序方式: 共有4548条查询结果,搜索用时 0 毫秒
991.
Scala Irene Bellavia Simone Luigetti Marco Brunetti Valerio Broccolini Aldobrando Gabrielli Maurizio Zileri Dal Verme Lorenzo Calabresi Paolo Della Marca Giacomo Frisullo Giovanni 《Neurological sciences》2022,43(8):4635-4643
Neurological Sciences - Evidence is emerging about an extra-pulmonary involvement of SARS-CoV-2, including the nervous system. Autonomic dysfunction in patients recovering from acute coronavirus... 相似文献
992.
Carelli V Franceschini F Venturi S Barboni P Savini G Barbieri G Pirro E La Morgia C Valentino ML Zanardi F Violante FS Mattioli S 《Environmental health perspectives》2007,115(1):113-115
CONTEXT: Leber hereditary optic neuropathy (LHON) is a maternally inherited loss of central vision related to pathogenic mutations in the mitochondrial genome, which are a necessary but not sufficient condition to develop the disease. Investigation of precipitating environmental/occupational (and additional genetic) factors could be relevant for prevention. CASE PRESENTATION: After a 6-month period of occupational exposure to n-hexane and other organic solvents, a 27-year-old man (a moderate smoker) developed an optic neuropathy. The patient had a full ophthalmologic and neurologic investigation, including standardized cycloergometer test for serum lactic acid levels and a skeletal muscle biopsy. His exposure history was also detailed, and he underwent genetic testing for LHON mitochondrial DNA mutations. The patient suffered a sequential optic neuropathy with the hallmarks of LHON and tested positive for the homoplasmic 11778G--> A/ND4 mutation. Routine laboratory monitoring revealed increased concentrations of urinary 2.5 hexandione (n-hexane metabolite) and hippuric acid (toluene metabolite) in the period immediately preceding the visual loss. DISCUSSION: In a subject carrying an LHON mutation, the strict temporal sequence of prolonged appreciable occupational exposure followed by sudden onset of visual loss must raise a suspicion of causality (with a possible further interaction with tobacco smoke). RELEVANCE: In this article, we add to the candidate occupational/environmental triggers of LHON and highlight the need for appropriate case-control (and laboratory) studies to validate the causal effect of mixed toxic exposures. 相似文献
993.
Luca Calabrese Giacomo Pietrobon Enrico Fazio Monir Abousiam Shadi Awny Roberto Bruschini Remo Accorona 《Head & neck》2020,42(5):1105-1109
The mainstream of treatment of early‐stage oral tongue squamous cell carcinoma (OTSCC) is represented by transoral resection with “adequate” free margins. Despite that, a precise and shared definition of “adequate margin” is lacking, and so is a standardized transoral surgical technique.The tongue is a symmetrically paired organ, consisting of intertwining intrinsic and extrinsic muscles, which can be distinguished during dissection. Routes of tumoral spread in oral tongue cancer are well‐known and should be taken into account during resection. We propose herein a standardized and replicable surgical technique to resect early‐stage OTSCC, based on rational anatomical considerations. 相似文献
994.
995.
996.
997.
998.
999.
Claudia Fabiani Antonio Vitale Donato Rigante Giacomo Emmi Giuseppe Lopalco Gerardo Di Scala 《Ocular immunology and inflammation》2020,28(2):298-304
ABSTRACTPurpose: To identify factors associated with sustained response to interleukin (IL)-1 inhibition among demographic, clinical and therapeutic data in patients with Behçet disease (BD).Methods: BD patients treated with anakinra or canakinumab were enrolled. Patients were divided into two groups according to the clinical response: group 1 included subjects showing a treatment duration of at least 52 weeks and no secondary inefficacy during the first follow-up year; the remaining patients were included in the group 2. Demographic, clinical and therapeutic data were analyzed to identify significant differences between groups.Results: Eighteen patients were included in group 1 and 18 patients in group 2. A better response to IL-1 inhibitors was significantly more common among patients with BD-related uveitis (p = 0.006) and patients with a longer disease duration (p = 0.03).Conclusion: IL-1 blockade is effective in BD, especially in the subset of patients presenting eye involvement and in those with long-lasting disease. 相似文献
1000.
Luigia Brugliera Massimo Filippi Ubaldo Del Carro Calogera Butera Francesca Bianchi Paola Castellazzi Paolo Cimino Paolo Capodaglio Giacomo Monti Pietro Mortini Luca G. Pradotto Lorenzo Priano Alfio Spina Sandro Iannaccone 《Archives of physical medicine and rehabilitation》2021,102(3):359-362
BackgroundProne positioning improves oxygenation in adult respiratory distress syndrome. This procedure has been widely used during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. However, this procedure can also be responsible for nerve damage and plexopathy.MethodsWe retrospectively reviewed a series of 7 infectious patients with coronavirus disease 2019 who underwent prone positioning ventilation at the San Raffaele Hospital of Milan, Italy, during the SARS-CoV-2 pandemic.ResultsClinical and neurophysiological data of 7 patients with nerve compression injuries have been reported.ConclusionsHealth care workers should take into consideration the risk factors for prone positioning–related plexopathy and nerve damage, especially in patients with coronavirus disease 2019, to prevent this type of complication. 相似文献