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61.
Nicola Crea Giacomo Pata Ernesto Di Betta Amin Titi Francesco Mittempergher 《Obesity surgery》2011,21(2):151-156
Although the appendix has been recognized as a preferential site for carcinoid tumors in obese patients, no definitive guidelines
are so far available regarding the management of these patients when candidates for bariatric surgery. This study was designed
to fill that gap. Between 2000-2008, 558 patients underwent bariatric procedures. Appendectomy was routinely performed in
477 cases. Their charts were retrospectively retrieved and histopathology responses on surgical specimens were recorded. We
aimed to assess: incidence of appendix carcinoid tumors (ACTs) and any possible risk-factor; modality of diagnosis (pre-,
intra- or post-operatively); impact on the planned bariatric procedure; treatment reserved to such cases. Typical ACTs were
diagnosed in 7 patients (1.4%) (median age: 33 years; median BMI: 49 kg/m2; males/females: 1/6). Four were diagnosed intra-operatively.
Because of dimensions (<2 cm) and absence of mesoappendiceal or serosal involvement, simple appendectomy was performed during
bariatric procedure, as planned. Three were diagnosed post-operatively (all <2 cm). In 1 case right hemicolectomy was performed
1 month later due to mesoappendiceal involvement. No appendectomy-related complication was encountered. All patients remained
tumor-free during follow-up (mean: 64 months; range, 25-92). Young age, female sex, high BMI and diabetes mellitus resulted
significantly associated with ACT. Our study sustains routine appendectomy or at least careful investigation of the appendix
during bariatric surgery. For tumors <2 cm without mesoappendiceal or serosal involvement, simple appendectomy proved sufficient.
Bariatric surgery did not have a negative effect on the treatment of malignancies that are discovered intra- or post-operatively. 相似文献
62.
63.
64.
Primary cardiac T-cell lymphoma 总被引:1,自引:0,他引:1
Giunta R Cravero RG Granata G Sellitto A Romano C De Fanis U Foccillo G De Capite C Santini M Rossiello L Rossiello R Lucivero G 《Annals of hematology》2004,83(7):450-454
Primary cardiac lymphoma (PCL), defined as a lymphoma clinically mimicking cardiac disease, with the bulk of the tumor located intrapericardially, is extremely rare in immunocompetent patients. Clinical manifestations vary depending on sites of involvement in the heart and include chest pain, arrhythmias, pericardial effusion, and heart failure. Diagnosis is often difficult and may require invasive procedures; in some cases, diagnosis is not made until autopsy. Histologically, nearly all cases of PCL reported thus far have been of B-cell origin. In this report, we describe a case of PCL of T-cell origin in an adult immunocompetent patient, the second reported in the literature to the best of our knowledge, and provide a brief overview of the features of previously published PCL cases. 相似文献
65.
66.
Ghyslaine Bruna Djeunang Dongho Karthigayan Gunalan Mariangela LEpiscopia Giacomo Maria Paganotti Michela Menegon Rose Efeutmecheh Sangong Georges Bouting Mayaka Joseph Fondop Carlo Severini Martin Sanou Sobze Louis H. Miller Gianluca Russo 《The American journal of tropical medicine and hygiene》2021,104(3):987
67.
68.
Simon Rauch Tomas Dal Cappello Giacomo Strapazzon Martin Palma Francesco Bonsante Elisabeth Gruber Mathias Ströhle Peter Mair Hermann Brugger 《The American journal of emergency medicine》2018,36(10):1749-1753
Objective
We investigated pre-hospital times, clinical characteristics and therapeutic interventions in multisystem trauma patients injured in mountainous areas in comparison to both urban and suburban trauma patient admissions.Methods
Pre-hospital and in-hospital data collected from trauma patients included in the International Alpine Trauma Register (IATR) hosted in Bolzano, Italy (aged 16–80?yr with an ISS?≥?16), were compared with trauma patient data published from those urban and suburban areas included in the Trauma Register DGU® (TR-DGU) of the German Trauma Society.Results
A total of 94 patients from the IATR and 11,020 patients from the TR-DGU met the inclusion criteria. Due to longer treatment-free intervals (mean 59.1 vs. 19.7?min), total out-of-hospital time was reportedly longer in individuals injured in mountainous areas, compared to urban/suburban areas (117.4?±?142.9 vs. 68.7?±?28.6?min, p?=?0.002), despite the more frequent helicopter rescue (93% vs. 40%, p?<?0.001). 57% of IATR patients were hypothermic at hospital arrival, mean ISS was higher (38.5?±?15.8 vs. 28.6?±?12.2, p?<?0.001) and patients with a systolic blood pressure (SBP) ≤90?mm?Hg were more frequent (27% vs. 15%, p?=?0.005), yet less patients had received volume therapy (82% vs. 93%, p?=?0.001). However, overall no difference in hospital mortality was observed (11% vs. 17%, p?=?0.159).Conclusion
Trauma incidents in mountainous areas commonly feature significantly increased out-of-hospital time which is associated with a more severe ISS, higher risk of accidental hypothermia and more frequent hypotension compared to urban/suburban trauma. Nonetheless, the mortality rate of IATR patients is comparable to urban/suburban trauma patients. 相似文献69.
Lorenzin Mariagrazia Ortolan Augusta Cozzi Giacomo Calligaro Antonia Favaro Maria Del Ross Teresa Doria Andrea Ramonda Roberta 《Clinical rheumatology》2021,40(11):4569-4580
Clinical Rheumatology - We aimed to evaluate the (a) potential predictors of first biological disease-modifying anti-rheumatic drug (bDMARD) failure and (b) factors associated with failure of... 相似文献
70.
De Lorenzis Enrico Natalello Gerlando Bruno Dario Tanti Giacomo Magurano Maria Rosaria Lucchetti Donatella Di Mario Clara Tolusso Barbara Peluso Giusy Gremese Elisa 《Clinical rheumatology》2021,40(5):1893-1902
Clinical Rheumatology - Depression is commonly associated with psoriatic arthritis (PsA), but its risk factors in these patients are largely unrecognized. Pro-inflammatory cytokines involved in the... 相似文献