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Hossein Khorramdelazad Gholamhossein Hassanshahi Behzad Nasiri Ahmadabadi Mohammad Kazemi Arababadi 《Hepatitis monthly》2012,12(11)
Background
The transforming growth factor-β (TGF-β) is an important cytokine with anti-inflammatory properties.Objectives
The main purpose of this study was to compare the serum levels of TGF-β in a group of chronic HBV infected (CHB) patients as well as healthy individuals from South-East of Iran.Patients and Methods
Sixty patients with CHB as well as sixty healthy individuals were enrolled in the study. ELISA technique was applied to measure the serum levels of TGF-β in both groups.Results
Our results revealed that the serum levels of TGF-β were significantly increased in CHB patients in compare to healthy controls.Conclusions
According to this result, it may be concluded that high serum levels of TGF-β may be a mechanism by which immune response against HBV is suppressed. 相似文献84.
Mazyar Ziyaeyan Abdolvahab Alborzi Marziyeh Jamalidoust Mahsa Moeini Gholam R. Pouladfar Bahman Pourabbas Mandana Namayandeh Mohsen Moghadami Kamran Bagheri‐Lankarani Talat Mokhtari‐Azad 《Influenza and other respiratory viruses》2012,6(6):e80-e84
Please cite this paper as: Ziyaeyan et al. (2012) Pandemic 2009 influenza A H1N1 infection among 2009 Hajj Pilgrims from Southern Iran: a real‐time RT‐PCR‐based study. Influenza and Other Respiratory Viruses 6(601), e80–e84. Background Hajj is a mass gathering undertaken annually in Mecca, Saudi Arabia. The 2009 Hajj coincided with both the pandemic influenza A/H1N1 2009 (A(H1N1)pdm09) and seasonal types of influenza A viruses. The interaction between pandemic influenza and Hajj could cause both a high level of mortality among the pilgrims and the spread of infection in their respective countries upon their return home. Objective The present study attempted to determine the point prevalence of A(H1N1)pdm09 among returning Iranian pilgrims, most of whom had been vaccinated for seasonal influenza but not A(H1N1)pdm09. Methods Pharyngeal swabs were collected from 305 pilgrims arriving at the airport in Shiraz, Iran. RNA was extracted from the samples and A(H1N1)pdm09 and other seasonal influenza A viruses were detected using TaqMan real‐time PCR. For A(H1N1)pdm09‐positive samples, the sensitivity to oseltamivir was also evaluated. Results Subjects included 132 (43·3%) men and 173 (56·7%) women, ranging in age from 24 to 65 years. The A(H1N1)pdm09 virus was detected in five (1·6%) pilgrims and other influenza A viruses in eight (2·6%). All the A(H1N1)pdm09 were sensitive to oseltamivir. Conclusions Only five cases were found to be positive for A(H1N1)pdm09, and it seems unlikely that the arrival of infected pilgrims to their homelands would cause an outbreak of a new wave of infection there. Thus, the low morbidity and mortality rates among the pilgrims could be attributed to the characteristics of A(H1N1)pdm09, which causes morbidity and mortality in a way similar to the seasonal influenza infections, absence of high‐risk individuals among the Iranian pilgrims, and the instructions given to them about contact and hand hygiene, and respiratory etiquette. 相似文献
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The aim of this in vitro study was to assess the effect of Er:YAG laser surface treatment on the tensile bond strength of
a sealant in permanent teeth. A total of 30 sound third molars were selected and embedded in cold-cure acrylic resin. The
enamel surfaces were flattened by a grinding. The teeth were randomly divided into three groups and pretreated as follows:
(1) 37% phosphoric acid; (2) Er:YAG laser (1.5 ml/min water spray, 100 mJ energy output, 10 Hz frequency, focal distance 17 mm);
(3) Er:YAG laser + 37% phosphoric acid. The treated surfaces were isolated by double adhesive Sellotape and after insertion
of a split Teflon matrix at an isolated site, sealant was applied. The specimens were thermocycled and stored at 37°C in distilled
water for 72 h, then subjected to a tensile bond strength test (50 kgf at 0.5 mm/min). The mean tensile bond strengths (±SD,
in megapascals) were: 18.51±5.68 in group 1, 8.06±2.69 in group 2, and 17.33±5.04 in group 3. Data were submitted to analysis
of variance and the Tukey test. No significant difference were found between groups 1 (37% phosphoric acid) and group 3 (Er:YAG
laser + 37% phosphoric acid) but treatment with the Er:YAG laser alone (group 2) resulted in significantly lower tensile bond
strength than seen in the other groups. In this setting, the Er:YAG laser prepared the enamel surface for sealing but did
not eliminate the need for acid etching before sealant application. 相似文献
89.
Hossein Ebrahimi Ali Abbasi Hossein Bagheri Mohammad Hasan Basirinezhad Sara Shakeri Reza Mohammadpourhodki 《Patient education and counseling》2021,104(1):130-135
ObjectiveThis study aimed to assess the effect of peer education on the quality of life and self-care behaviors of patients with myocardial infarction.MethodsIn this clinical trial, 70 patients with myocardial infarction meeting the inclusion criteria were assigned to experimental (n = 35) or control (n = 35) groups using block randomization. Patients in the intervention group received two one-hour training sessions on the third day after myocardial infarction during the CCU stay along with routine care. Education intervention was performed by peers. The control group will follow routine care. All patients selected were assessed using McNews' quality of life questionnaire and Miller self-care questionnaire, respectively before the intervention and also one month after discharge. Chi-square and t-test were used to analyze the data.ResultsAfter the intervention, the mean of quality of life and the mean score of self-care behaviors in the experimental group were significantly higher compared to the control group.ConclusionsAccording to the results, to improve the quality of life and promote the self-care behaviors in such patients, using peer education along with healthcare professionals is recommended.Practice ImplicationThis patient education approach had a significant impact on quality of life and self-care behavior. 相似文献
90.
Jean-Baptiste Bouillon-Minois Justin Outrey Bruno Pereira Oluwaseun John Adeyemi Vincent Sapin Damien Bouvier David Thivel Sarah de Saint-Vincent Ukadike Chris Ugbolue Julien S. Baker Reza Bagheri Jeannot Schmidt Marion Trousselard Frdric Dutheil 《Nutrients》2022,14(23)
Despite the available literature on the consequences of night shiftwork on stress and food intake, its impact on leptin and ghrelin has never been studied. We previously demonstrated that leptin and ghrelin were biomarkers related to stress, and acute stress-induced a decrease in leptin levels and an increase in ghrelin levels. We performed a prospective observational study to assess the influence of night work, nutrition, and stress on the levels of ghrelin and leptin among emergency healthcare workers (HCWs). We took salivary samples at the beginning of a day shift and/or at the end of a night shift. We also monitored stress using the job demand-control-support model of Karasek. We recorded 24-h food intake during the day shift and the consecutive night shift and during night work and the day before. We included 161 emergency HCWs. Emergency HCWs had a tendency for decreased levels of leptin following the night shift compared to before the dayshift (p = 0.067). Furthermore, the main factors explaining the decrease in leptin levels were an increase in job-demand (coefficient −54.1, 95 CI −99.0 to −0.92) and a decrease in job control (−24.9, −49.5 to −0.29). Despite no significant changes in ghrelin levels between shifts, social support was the main factor explaining the increase in ghrelin (6.12, 0.74 to 11.5). Food intake (kcal) also had a negative impact on leptin levels, in addition to age. Ghrelin levels also decreased with body mass index, while age had the opposite effect. In conclusion, we confirmed that ghrelin and leptin as biomarkers of stress were directly linked to the job demand-control-support model of Karasek, when the main cofounders were considered. 相似文献