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131.
Nikki H. Stricker Jenna E. Keller Diane T. Castillo Kathleen Y. Haaland 《Journal of traumatic stress》2015,28(2):102-109
Neurocognitive problems are common with posttraumatic stress disorder (PTSD) and are important to understand because of their association with the success of PTSD treatment and its potential neural correlates. To our knowledge, this is the first neurocognitive study in an all‐female U.S. veteran sample, some of whom had PTSD. We examined neurocognitive performance and assessed whether learning deficits, common in PTSD, were associated with executive functioning. Veterans with PTSD (n = 56) and without (n = 53) were evaluated for psychiatric and neurocognitive status. The PTSD group had a lower estimated IQ (d = 0.53) and performed more poorly on all neurocognitive domains (d range = 0.57–0.88), except verbal retention (d = 0.04). A subset of the 2 groups that were matched on IQ and demographics similarly demonstrated poorer performance for the PTSD group on all neurocognitive domains (d range = 0.52–0.79), except verbal retention (d = 0.15). Within the PTSD group, executive functioning accounted for significant variance in verbal learning over and above IQ and processing speed (ΔR2 = .06), as well as depression (ΔR2 = .07) and PTSD severity (ΔR2 = .06). This study demonstrated that female veterans with PTSD performed more poorly than females without PTSD on several neurocognitive domains, including verbal learning, processing speed, and executive functioning. Replication of these results using a control group of veterans with more similar trauma exposure, history of mild traumatic brain injury, and psychiatric comorbidities would solidify these findings. 相似文献
132.
Effect of Preoperative Occlusal Matrices on the Vickers Microhardness of Composite Disks Polymerized with QTH and LED Lamps 下载免费PDF全文
133.
Preclinical cadaveric study of transanal robotic proctectomy with total mesorectal excision combined with laparoscopic assistance 下载免费PDF全文
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Natalia R. Genaro M.D. Daniel D. Anselm M.D. Nahuel Cervino M.D. Ariel O. Estevez M.D. Carlos Perona M.D. Alejandro M. Villamil M.D. Ruben Kervorkian M.D. Adrian Baranchuk M.D. 《Annals of noninvasive electrocardiology》2014,19(4):387-390
Brugada phenocopies (BrP) are clinical entities that are etiologically distinct from true congenital Brugada syndrome (BrS). BrP are characterized by type 1 or type 2 Brugada electrocardiogram (ECG) patterns in precordial leads V1–V3; however, BrP are elicited by various underlying clinical conditions such as electrolyte disturbances, myocardial ischemia, or poor ECG filters. In this report, we describe the first case of clinically reproducible BrP which is important to the conceptual evolution of BrP. 相似文献
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J. Costa‐Pinto A. Pérez‐Rodríguez M. del C. Goméz‐del‐Castillo E. Lourés Á. Rodríguez‐Trillo J. Batlle M. F. López‐Fernández 《Haemophilia》2014,20(4):559-567
Diagnostics of von Willebrand disease (VWD) includes assessment of factor VIII (FVIII) coagulant activity, von Willebrand factor (VWF) antigen (VWF:Ag) and VWF ristocetin cofactor activity (VWF:RCo), and more specific tests as multimeric and genetic analyses are necessary for the correct VWD classification. The ACL AcuStar? analyzer introduces chemiluminescence (CL) technology in detection of VWD with automated VWF:Ag and VWF:RCo assays. Compare VWF:Ag‐ELISA and VWF:RCo by aggregometry conventional assays with new CL VWF:Ag‐IL and VWF:RCo‐IL assays, investigate the ability to make accurate VWD diagnosis and concordance with multimeric and genetic analyses. 146 patients with congenital VWD (51 Type 1; 34 Type2A; 16 Type 2B; 31 Type 2M; 5 Type 2N; 9 Type 3) and 30 healthy normal subjects were included. A comparison was made between CL and conventional methods. Diagnostic evaluation included: VWF:RCo/VWF:Ag ratio, multimeric distribution (sodium dodecyl sulfate [SDS]‐agarose gel) of VWF and genetic analysis in 110 of 146 patients. CL and conventional methods revealed good correlation. Kappa test agreement diagnosis was >0.8. CL diagnostic sensitivity was 100% and specificity 97%. Multimeric and genetic analysis were of help in clarifying 13 discrepancies of diagnosis between methods, of which six discrepancies were explained by lack of conventional methods′ sensibility. CL methodology can detect VWD and discriminate between type 1, 3 and variant forms and offers an automated, faster, sensitive and less cumbersome method when compared to conventional assays, in particular VWF:RCo by aggregometry. In some cases, even with all phenotype and genetic analyses, discrepancies exist in the classification of VWD. 相似文献
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A. Esteban-Gil C. Grisez F. Prevot S. Florentin A. Decaudin N. Picard-Hagen X. Berthelot P. Ronsin J. P. Alzieu M. Marois N. Corboz M. Peglion C. Vilardell E. Liénard E. Bouhsira J. A. Castillo M. Franc P. Jacquiet 《Parasitology research》2014,113(6):2355-2362
Bovine besnoitiosis is a chronic and debilitating disease observed in many European countries that may cause important economic losses in cattle. The recent widespread of the parasite in Europe had led the European Food Safety Authority to declare bovine besnoitiosis as a re-emerging disease in Europe. Many aspects of the epidemiology of bovine besnoitiosis such as the main routes of transmission are still unclear and need to be further studied. Among the different hypotheses, a sexual transmission has not yet been investigated. Therefore, the aim of this study was to evaluate the presence of Besnoitia besnoiti DNA in the semen of naturally infected bulls by using a highly sensitive method (real-time qPCR). Both pre-sperm and sperm fractions of 40 bulls, including seronegative (n?=?11), seropositive subclinically (n?=?17), and seropositive clinically (n?=?12) infected animals, were collected by electroejaculation and analyzed by real-time qPCR. No B. besnoiti DNA was detected in 27 pre-sperm and 28 sperm fractions of the 40 examined bulls, suggesting that the transmission of B. besnoiti infection by the semen of chronically infected bulls is very unlikely. 相似文献