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Association between disease activity and quality of life in ulcerative colitis: Results from the CRONICA‐UC study
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The effects were analysed of a unilateral lesion in the anterior or medial hypothalamus made on the day of oestrus on right or left hemicastrated rats. On the day of oestrus after two consecutive oestrous cycles of the same length, the ovulation rate in rats with lesions in the anterior left hypothalamus was lower than in control hemicastrated animals (5/16 vs 18/20; P less than 0.01), and normal in those rats with lesions in the right side (14/18). None of the animals with lesions in the left side of the anterior hypothalamus and with the left ovary in situ ovulated (0/7), but 5/9 with the right ovary in situ did ovulate (P less than 0.05). Lesions on either side of the medial hypothalamus did not modify ovulation rate. Compensatory ovulation was reduced in those animals with lesions in the right anterior hypothalamus and with the right ovary in situ. Lesions in either side of the medial hypothalamus reduced compensatory ovulation. Lesions in the right side of the anterior and medial hypothalamus increased compensatory ovarian hypertrophy in the left ovary and decreased it in the right ovary. Lesions in the left side of the anterior hypothalamus increased compensatory ovarian hypertrophy in the left ovary only, whereas lesions in the left side of the medial hypothalamus reduced compensatory ovarian hypertrophy in the right ovary. The results suggest that the information arising in each side of the anterior and medial hypothalamus plays different roles in the ipsi-and contralateral ovary, when either the left or the right ovary is absent. 相似文献
127.
León-Carrión J Domínguez-Morales Mdel R Barroso y Martín JM Murillo-Cabezas F 《Pituitary》2005,8(3-4):197-202
Incidence rates of traumatic brain injury are high in both industrialized and non-industrialized countries and have been estimated
variously to be between 150–250 cases per 100,000 population per year. The estimated incidence rates for subarachnoid hemorrhage
(SAH) are between 10 to 25 cases per 100,000 population per year. Seasonal variation in the occurrence of subarachnoid hemorrhage
has been reported in studies from different countries, with significant seasonal variations and peak periods for aneurysmal
SAH differing widely. A differential racial distribution for SAH has been found as well as a higher mortality rate for women
than for men. The cognitive and behavioral consequences of TBI and SAH are significant and affect the quality of life of patients
and their families. Recent publications have informed of hypopituitary deficits in patients sustaining TBI or SAH. It is not
clear whether the cognitive deficits found in these patients are due to the consequences of the brain injury itself or are
related to the hypopituitary deficits. There is a need for research distinguishing the differential cognitive and behavioral
effects of the brain injury and the endocrinological deficits in these patients, and for developing adequate treatment. 相似文献
128.
A Moreno-Ancillol C Domínguez-Noche A C Gil-Adrados P M Cosmes 《Journal of investigational allergology & clinical immunology》2004,14(2):165-167
Hypersensitivity pneumonitis or extrinsic allergic alveolitis can be defined as a lung disease caused by a wide group of antigens that reach the lung by inhalation of organic and/or inorganic dust of various sources. The dust of the stored maize corn has been reported as cause of respiratory symptoms. During the storage process, maize corn dust can be contaminated by moulds and thermophilic actinomycetes, which have not been described until now as the causing antigens of these symptoms. We present a case of occupational hypersensitivity pneumonitis in an agricultural worker who cultured and stored maize corn. Clinical findings, precipitating antibodies, and evolution after having removed him from his work, confirmed the diagnosis. In our case, Aspergillus species contaminating the maize corn dust are probably the antigens that caused the disease. 相似文献
129.
Seijo Ríos S Lariño Noia J Iglesias García J Lozano León A Domínguez Muñoz JE 《Gastroenterologia y hepatologia》2008,31(2):92-97
Primary cystic pancreatic neoplasms are rare tumors, with an approximate prevalence of 10% of cystic pancreatic lesions. Most of these lesions correspond to mucinous cystic neoplasm, serous cystoadenoma and intraductal papillary mucinous tumor (IPMT). IPMT is characterized by diffuse dilatation of the main pancreatic duct and/or side branches with inner defects related to mucin or tumor, or mucin extrusion from a patent ampulla. IPMT has a low potential for malignancy, with a low growth rate, a low rate of metastatic spread and postsurgical recurrence. Over the last few years, major advances have been made in the diagnostic and therapeutic management of this tumor. 相似文献
130.
Marjolijn Duijvestein Robert Battat Niels Vande Casteele Geert R. D’Haens William J. Sandborn Reena Khanna Vipul Jairath Brian G. Feagan 《Current Treatment Options in Gastroenterology》2018,16(1):129-146