全文获取类型
收费全文 | 1865篇 |
免费 | 111篇 |
国内免费 | 6篇 |
专业分类
耳鼻咽喉 | 18篇 |
儿科学 | 103篇 |
妇产科学 | 14篇 |
基础医学 | 179篇 |
口腔科学 | 48篇 |
临床医学 | 143篇 |
内科学 | 410篇 |
皮肤病学 | 37篇 |
神经病学 | 95篇 |
特种医学 | 78篇 |
外科学 | 345篇 |
综合类 | 26篇 |
一般理论 | 1篇 |
预防医学 | 45篇 |
眼科学 | 179篇 |
药学 | 147篇 |
中国医学 | 4篇 |
肿瘤学 | 110篇 |
出版年
2024年 | 1篇 |
2023年 | 31篇 |
2022年 | 66篇 |
2021年 | 132篇 |
2020年 | 75篇 |
2019年 | 83篇 |
2018年 | 105篇 |
2017年 | 55篇 |
2016年 | 96篇 |
2015年 | 86篇 |
2014年 | 121篇 |
2013年 | 142篇 |
2012年 | 202篇 |
2011年 | 203篇 |
2010年 | 98篇 |
2009年 | 68篇 |
2008年 | 101篇 |
2007年 | 82篇 |
2006年 | 61篇 |
2005年 | 50篇 |
2004年 | 43篇 |
2003年 | 30篇 |
2002年 | 20篇 |
2001年 | 5篇 |
2000年 | 4篇 |
1998年 | 4篇 |
1997年 | 2篇 |
1996年 | 3篇 |
1994年 | 1篇 |
1991年 | 1篇 |
1990年 | 1篇 |
1989年 | 1篇 |
1987年 | 1篇 |
1986年 | 1篇 |
1985年 | 1篇 |
1982年 | 1篇 |
1980年 | 1篇 |
1979年 | 1篇 |
1978年 | 1篇 |
1976年 | 2篇 |
排序方式: 共有1982条查询结果,搜索用时 46 毫秒
21.
22.
Jeff Reeve Georg A. Böhmig Farsad Eskandary Gunilla Einecke Gaurav Gupta Katelynn Madill‐Thomsen Martina Mackova Philip F. Halloran INTERCOMEX MMDx‐Kidney Study Group 《American journal of transplantation》2019,19(10):2719-2731
We previously reported a system for assessing rejection in kidney transplant biopsies using microarray‐based gene expression data, the Molecular Microscope® Diagnostic System (MMDx). The present study was designed to optimize the accuracy and stability of MMDx diagnoses by replacing single machine learning classifiers with ensembles of diverse classifier methods. We also examined the use of automated report sign‐outs and the agreement between multiple human interpreters of the molecular results. Ensembles generated diagnoses that were both more accurate than the best individual classifiers, and nearly as stable as the best, consistent with expectations from the machine learning literature. Human experts had ≈93% agreement (balanced accuracy) signing out the reports, and random forest‐based automated sign‐outs showed similar levels of agreement with the human experts (92% and 94% for predicting the expert MMDx sign‐outs for T cell–mediated (TCMR) and antibody‐mediated rejection (ABMR), respectively). In most cases disagreements, whether between experts or between experts and automated sign‐outs, were in biopsies near diagnostic thresholds. Considerable disagreement with histology persisted. The balanced accuracies of MMDx sign‐outs for histology diagnoses of TCMR and ABMR were 73% and 78%, respectively. Disagreement with histology is largely due to the known noise in histology assessments (ClinicalTrials.gov NCT01299168). 相似文献
23.
24.
David D. Berg Muthiah Vaduganathan Gaurav A. Upadhyay Jagmeet P. Singh Mandeep R. Mehra Garrick C. Stewart 《Journal of the American College of Cardiology》2018,71(13):1483-1493
Recent progress and evolution in device engineering, surgical implantation practices, and periprocedural management have advanced the promise of durable support with left ventricular assist systems (LVAS) in patients with stage D heart failure. With greater uptake of LVAS globally, a growing population of LVAS recipients have pre-existing cardiac implantable electronic devices (CIEDs). Strategies for optimal clinical management of CIEDs in patients with durable LVAS are evolving, and clinicians will increasingly face complex decisions regarding implantation, programming, deactivation, and removal of CIEDs. Traditional decision-making pathways for CIEDs may not apply to LVAS-supported patients, as few patients die of arrhythmic causes and many arrhythmias may be well tolerated. Given limited data, treatment decisions must be individualized and made collaboratively among electrophysiologists, advanced heart failure specialists, and patients and their caregivers. Large, prospective, well-conducted studies are needed to better understand the contemporary utility of CIEDs in patients with newer-generation LVAS. 相似文献
25.
Gaurav Kumar Upadhyaya Ajay Shukla Vijay Kumar Jain Skand Sinha R.K. Arya Ananta Kumar Naik 《Journal of Clinical Orthopaedics and Trauma》2016,7(1):45-49
Fracture of isolated spinous processes at multiple levels is a rare injury. Herein, we present a 45-year-old male with cervical pain and swelling following a road traffic accident. Computerized tomography and magnetic resonance imaging revealed fractures of spinous process from C7 to D6 vertebra. The patient was managed with rest, analgesics and immobilization. At the 1-year follow-up, the patient is doing well without any neurological problem. 相似文献
26.
Hair shaft disorders are characterized by congenital or acquired abnormalities of the hair shaft. The objective was to review the literature regarding the prognosis and treatment options of hair shaft disorders. We used keywords in the search engines PubMed and Medline to identify all publications in the English language related to the prognosis and management of hair shaft disorders. Data were extracted from 96 articles that met search criteria. Findings were limited to case reports and small case series, as no studies were found. Disorders that improve in childhood include pili torti, trichorrhexis invaginata, wooly hair, and pili trianguli et canaliculi. Others, such as trichorrhexis nodosa, monilethrix, pili annulati, and pili bifurcati improve with minoxidil. Oral retinoids have improved hair abnormalities in trichorrhexis invaginata and monilethrix. There is no specific treatment for congenital hair shaft abnormalities. Gentle hair care is the mainstay of care for hair shaft disorders associated with fragility. Practices for gentle care include no brushing, backcombing, chemical products, tight braids, heat exposure, or mechanical grooming. Any inherited or congenital disorder requires genetic counseling as part of management. 相似文献
27.
Hair shaft disorders are characterized by congenital or acquired abnormalities of the hair shaft. The objective of this study was to review the literature regarding the prognosis and treatment options for hair shaft disorders. We used keywords in the search engines PubMed and Medline to identify all publications in English related to the prognosis and management of hair shaft disorders. Data were extracted from 96 articles that met search criteria. Findings were limited to case reports and small case series, as no studies were found. Disorders that improve in childhood include pili torti, trichorrhexis invaginata, woolly hair, and pili trianguli et canaliculi. Others, such as trichorrhexis nodosa, monilethrix, pili annulati, and pili bifurcati, improve with minoxidil. Oral retinoids have been found to improve hair abnormalities in trichorrhexis invaginata and monilethrix. There is no specific treatment for congenital hair shaft abnormalities. Gentle hair care is the mainstay of care for hair shaft disorders associated with fragility. Practices for gentle care include no brushing, backcombing, chemical products, tight braids, heat exposure, or mechanical grooming. Furthermore, any inherited or congenital disorder requires genetic counseling as part of management. 相似文献
28.
29.
30.