Development of a condition-specific quality of life measure for patients with dentofacial deformity: II. Validity and responsiveness testing

The assessment of quality of life is becoming increasingly important in dentistry. This may be measured using two groups of instruments: generic and condition-specific. OBJECTIVES: This paper describes the processes of validity and responsiveness testing of a condition-specific quality of life measure for patients who present with severe dentofacial deformity requesting orthognathic treatment (the so-called Orthognathic Quality of Life Questionnaire). The development of the instrument is described in a previous paper. METHOD: The OQLQ was tested for validity using a visual analogue scale and also the Short-Form 36 health survey questionnaire. Responsiveness was tested using longitudinal data obtained before, during and after orthognathic treatment. RESULTS AND CONCLUSIONS: The OQLQ shows good evidence of validity and responsiveness. This, together with previous evidence of good reliability, suggests that the instrument may prove useful in both clinical trials and in quality assurance.     

Reliability,validity and psychometric properties of the Greek translation of the Major Depression Inventory

Background  

The Major Depression Inventory (MDI) is a brief self-rating scale for the assessment of depression. It is reported to be valid because it is based on the universe of symptoms of DSM-IV and ICD-10 depression. The aim of the current preliminary study was to assess the reliability, validity and psychometric properties of the Greek translation of the MDI.     

Responsiveness of generic and specific measures of health outcome in low back pain

STUDY DESIGN: A longitudinal study using patient questionnaires was performed. OBJECTIVE: To compare the discriminatory power and responsiveness of the Aberdeen Back Pain Scale (ABPS), the Roland Disability Questionnaire (RDQ), and the EuroQol in patients with low back pain. SUMMARY OF BACKGROUND DATA: A number instruments specific to low back pain have not been compared for measurement properties. The EuroQol is a widely used generic instrument that has not been compared with specific instruments in patients with back pain. METHODS: A questionnaire incorporating the Aberdeen Back Pain Scale, the Roland Disability Questionnaire, and the EuroQol was completed by patients taking part in a clinical trial of exercise treatments for back pain. Patients completed follow-up questionnaires at 6 weeks, 6 months, and 1 year. The discriminatory power of these instruments was assessed against variables relating to activity limitations, medication, and comorbidity. Responsiveness was assessed using standardized response means. RESULTS: The questionnaire was completed by 187 patients taking part in the clinical trial. The Aberdeen instrument was found to be the most powerful at discriminating between different groups of patients on variables relating to activity limitations, medication, and comorbidity. The specific instruments demonstrated good levels of responsiveness, with the Aberdeen instrument producing the largest standardized response means. The Aberdeen instrument was more responsive to the smaller changes experienced by the control group, but was less powerful than the Roland at measuring differences in the levels of change between the two groups of patients at two of the three follow-up assessments in the trial. The EuroQol demonstrated a moderate level of responsiveness. CONCLUSIONS: The two specific instruments are capable of greater levels of discrimination between groups of patients, and are more responsive over time than the generic EuroQol. The Aberdeen instrument performed most satisfactorily in relation to these criteria, but the Roland instrument was more sensitive to differences between the two groups in the clinical trial. The measurement properties of these two instruments reflect their origin: The Aberdeen instrument is based on clinical questions, whereas the Roland instrument is based on the generic Sickness Impact Profile. Instrument content should be carefullyconsidered when selecting instruments for applications, including clinical trials.     

The UK version of the Seattle Angina Questionnaire (SAQ-UK): reliability, validity and responsiveness

The study assesses the reliability, validity and responsiveness of the UK version of the Seattle Angina Questionnaire (SAQ-UK). The instrument was anglicised and administered by self-completed postal questionnaire to 959 patients recruited from general practices in the North East of England. A total of 655 (68.3%) patients returned a completed questionnaire. Principal component analysis produced three important dimensions: physical limitations, anginal frequency and perception and treatment satisfaction. Four items that performed poorly were removed from the instrument. The removal of items greatly increased the number of computable scale scores. Estimates of internal reliability for the three dimensions ranged from 0.83-0.92. Estimates of test-retest reliability were above accepted standards. The correlation between the SAQ-UK scores and the SF-12, EuroQol and health transition was evidence for the validity of the instrument. The SAQ-UK produced responsiveness statistics that were comparable to the parent instrument and was more responsive to improvements in health than the generic instruments. The SAQ-UK is recommended as a measure of health outcome for the evaluation of angina management.     

Recurrent urinary tract infection in girls. Group with lower tract findings and a benign course

A group of girls is described with recurrent urinary tract infections characterized by predominantly lower tract symptoms. Clinical, laboratory, and radiography findings during the period of follow-up are presented. Infection persisted in most patients over several years. Response to medical and surgical treatment was unsatisfactory. The mean interval between the initial and most recent radiological study was 6 1/2 years. No case of renal parenchymal scarring was seen.     

General practitioners' evaluation of community psychiatric services: responsiveness to change of the General Practitioner Experiences Questionnaire (GPEQ)

Background  

Instruments have been developed to assess professional views of the quality of care but have rarely been tested for responsiveness to change. The objective of this study was to test the responsiveness of the General Practitioner Experiences Questionnaire (GPEQ) for the measurement of Community Mental Health Centres in Norway.