全文获取类型
收费全文 | 1511249篇 |
免费 | 120221篇 |
国内免费 | 3581篇 |
专业分类
耳鼻咽喉 | 19909篇 |
儿科学 | 49633篇 |
妇产科学 | 43365篇 |
基础医学 | 214636篇 |
口腔科学 | 41361篇 |
临床医学 | 132431篇 |
内科学 | 309551篇 |
皮肤病学 | 36616篇 |
神经病学 | 124951篇 |
特种医学 | 56127篇 |
外国民族医学 | 464篇 |
外科学 | 223104篇 |
综合类 | 33324篇 |
现状与发展 | 3篇 |
一般理论 | 519篇 |
预防医学 | 120289篇 |
眼科学 | 33809篇 |
药学 | 105678篇 |
1篇 | |
中国医学 | 3849篇 |
肿瘤学 | 85431篇 |
出版年
2021年 | 13009篇 |
2019年 | 14091篇 |
2018年 | 20779篇 |
2017年 | 15111篇 |
2016年 | 16461篇 |
2015年 | 18474篇 |
2014年 | 25325篇 |
2013年 | 37681篇 |
2012年 | 53058篇 |
2011年 | 56074篇 |
2010年 | 32283篇 |
2009年 | 29893篇 |
2008年 | 50802篇 |
2007年 | 53784篇 |
2006年 | 53710篇 |
2005年 | 52111篇 |
2004年 | 49327篇 |
2003年 | 46866篇 |
2002年 | 45107篇 |
2001年 | 75448篇 |
2000年 | 77449篇 |
1999年 | 63700篇 |
1998年 | 17359篇 |
1997年 | 15660篇 |
1996年 | 15812篇 |
1995年 | 14964篇 |
1994年 | 13536篇 |
1993年 | 12704篇 |
1992年 | 46673篇 |
1991年 | 44189篇 |
1990年 | 42192篇 |
1989年 | 40111篇 |
1988年 | 36650篇 |
1987年 | 35819篇 |
1986年 | 33353篇 |
1985年 | 31683篇 |
1984年 | 24123篇 |
1983年 | 20261篇 |
1982年 | 12324篇 |
1981年 | 10882篇 |
1979年 | 20983篇 |
1978年 | 14753篇 |
1977年 | 12255篇 |
1976年 | 11532篇 |
1975年 | 11846篇 |
1974年 | 14252篇 |
1973年 | 13834篇 |
1972年 | 12884篇 |
1971年 | 11745篇 |
1970年 | 11170篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
31.
32.
33.
Ángel Becerra Héctor Trujillo Lucía Valencia Aurelio Rodríguez‐Pérez 《Brazilian Journal of Anesthesiology》2019,69(2):200-203
Background and objectives
A prompt and effective management of trauma patient is necessary. The aim of this case report is to highlight the importance of intraoperative echocardiography as a useful tool in patients suffering from refractory hemodynamic instability no otherwise explained.Case report
A 41 year‐old woman suffered a car accident. At the emergency department, no abnormalities were found in ECG or chest X‐ray. Abdominal ultrasound revealed the presence of abdominal free liquid and the patient was submitted to urgent exploratory laparotomy. Nevertheless, she persisted suffering arterial hypotension and metabolic acidosis. Looking for the reason of her hemodynamic instability, intraoperative transthoracic echocardiography was performed, finding out the presence of pericardial effusion. Once the cardiac surgeon extracted pericardial clots, patient's situation improved clinically and analytically.Conclusion
Every anesthesiologist should be able to use the intraoperative echocardiography as an effective tool in order to establish the appropriate measures to promote the survival of patients suffering severe trauma. 相似文献34.
Metabolism describes the series of chemical reactions that are concerned with the provision of energy to biological systems. They may be divided into reactions involved in energy yield (catabolism: demand exceeds supply), and energy storage (anabolism: supply exceeds demand). Regulation of these pathways is critical for homeostasis, and derangements in metabolism are seen in a wide variety of pathological processes. Understanding metabolism is key to the treatment of many diseases, notably diabetes, as well as underpinning clinical nutritional support. 相似文献
35.
Ali Mobasheri Csaba Matta Ilona Uzielienè Emma Budd Pablo Martín-Vasallo Eiva Bernotiene 《Joint, bone, spine : revue du rhumatisme》2019,86(1):29-35
Chondrocytes are the main cells in the extracellular matrix (ECM) of articular cartilage and possess a highly differentiated phenotype that is the hallmark of the unique physiological functions of this specialised load-bearing connective tissue. The plasma membrane of articular chondrocytes contains a rich and diverse complement of membrane proteins, known as the membranome, which defines the cell surface phenotype of the cells. The membranome is a key target of pharmacological agents and is important for chondrocyte function. It includes channels, transporters, enzymes, receptors, and anchors for intracellular, cytoskeletal and ECM proteins and other macromolecular complexes. The chondrocyte channelome is a sub-compartment of the membranome and includes a complete set of ion channels and porins expressed in these cells. Many of these are multi-functional proteins with “moonlighting” roles, serving as channels, receptors and signalling components of larger molecular assemblies. The aim of this review is to summarise our current knowledge of the fundamental aspects of the chondrocyte channelome, discuss its relevance to cartilage biology and highlight its possible role in the pathogenesis of osteoarthritis (OA). Excessive and inappropriate mechanical loads, an inflammatory micro-environment, alternative splicing of channel components or accumulation of basic calcium phosphate crystals can result in an altered chondrocyte channelome impairing its function. Alterations in Ca2+ signalling may lead to defective synthesis of ECM macromolecules and aggravated catabolic responses in chondrocytes, which is an important and relatively unexplored aspect of the complex and poorly understood mechanism of OA development. 相似文献
36.
37.
38.
39.
Autoimmune comorbid diseases associated with lichen planus: a nationwide case–control study 下载免费PDF全文
40.
Pradeep Balasubramanian M.D. C. R. Srinivas M.D. Pavai Arunachalam M.S. M.Ch. K. S. Thirumurthy M.S. M.Ch. P. R. Rajkumar M.S. M.Ch. H. Manuvidhya M.B.B.S. 《Pediatric dermatology》2015,32(3):e78-e81
We report on a child with several café au lait spots in association with a lumbar lipomeningomyelocele as an apparently new association. Cutaneous markers, the identification of which plays a crucial role in the early diagnosis and management of spinal malformations, can accompany occult spinal dysraphism. Herein we report a case of lumbar lipomeningomyelocele associated with an overlying café au lait spot that served as a marker of occult spinal dysraphism. The patient also had segmental café au lait spots on the face, making the association unique. 相似文献