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111.
CHUNZENG LU M.D. GIAN L. NICOLOSI M.D. CLAUDIO BURELLI M.D. MATTEO CASSIN M.D. FABIO ZARDO M.D. MARCO BRIEDA M.D. EUGENIO CERVESATO Ph.D. DOMENICO ZANUTTINI M.D. 《Echocardiography (Mount Kisco, N.Y.)》1994,11(3):207-213
To investigate the influence of changes in loading conditions on Doppler echocardiography determination of left ventricular ejection dynamics (peak aortic flow velocity and mean acceleration), pulsed Doppler was performed on 20 patients from apical 5-chamber view. Doppler aortic flow velocity curves and hemodynamic values (left ventricular pressure, wedge pressure, and cardiac output) and the first derivative of ventricular pressure (dPIdt) by tip-transducer catheter were simultaneously recorded at baseline and during intravenous infusion of nitroglycerin as well as at baseline and immediately following left ventriculography. During nitroglycerin infusion, the hemodynamic values were reduced and peakdPIdt remained constant, Doppler aortic peak velocity and mean acceleration decreased significantly compared with baseline (0.87 ± 0.11 mlsec vs 1.01 ± 0.14 mlsec and 8.86 ± 1.68 ml sec2 vs 10.17 ± 1.88 mlsec2 respectively; bothP < 0.001). After ventriculography, the hemodynamic values increased and peak dPIdt was still constant, Doppler aortic peak velocity and mean acceleration increased significantly compared with baseline (1.15 ± 0.17 mlsec vs 0.98 ± 0.16 mlsec and 11.44 ± 2.06 mlsec2 vs 9.79 ± 1.88 mlsec2 respectively;both P < 0.001). In conclusion, left ventricular ejection dynamics, as evaluated by pulsed Doppler echocardiography, is modified by mild changes in loading conditions. Therefore, when serially evaluating the inotropic state of the left ventricle by the Doppler aortic flow velocity pattern, the potential influence of loading conditions should be takeninto account. 相似文献
112.
GIAN CARLO TOPI LUCIANA D'ALESSANDRO CATERINA CATRICALA ORESTE ZARDI 《The British journal of dermatology》1979,101(5):589-591
A woman had the typical clinical, cutaneous, and muscular picture of dermatomyositis but without some of the biochemical alterations of that disease. The positive serological investigations for toxoplasmosis, the pressure in muscles of very numerous toxoplasms and their culture in mice, and the improvement after treatment with pyrimethamine and sulphametoxypyridine demonstrated that the signs of dermatomyositis had been caused by infection with toxoplasmosis. 相似文献