收费全文 | 1276516篇 |
免费 | 92735篇 |
国内免费 | 1987篇 |
耳鼻咽喉 | 18185篇 |
儿科学 | 42257篇 |
妇产科学 | 37812篇 |
基础医学 | 186987篇 |
口腔科学 | 35381篇 |
临床医学 | 108105篇 |
内科学 | 251429篇 |
皮肤病学 | 26497篇 |
神经病学 | 99171篇 |
特种医学 | 49981篇 |
外国民族医学 | 366篇 |
外科学 | 197579篇 |
综合类 | 26516篇 |
现状与发展 | 1篇 |
一般理论 | 300篇 |
预防医学 | 92581篇 |
眼科学 | 29056篇 |
药学 | 97756篇 |
1篇 | |
中国医学 | 2496篇 |
肿瘤学 | 68781篇 |
2018年 | 11808篇 |
2015年 | 11610篇 |
2014年 | 15994篇 |
2013年 | 24346篇 |
2012年 | 33544篇 |
2011年 | 35935篇 |
2010年 | 21206篇 |
2009年 | 20013篇 |
2008年 | 34973篇 |
2007年 | 37940篇 |
2006年 | 38497篇 |
2005年 | 37792篇 |
2004年 | 36377篇 |
2003年 | 35367篇 |
2002年 | 34915篇 |
2001年 | 58093篇 |
2000年 | 59584篇 |
1999年 | 50686篇 |
1998年 | 14232篇 |
1997年 | 12809篇 |
1996年 | 13071篇 |
1995年 | 12345篇 |
1994年 | 11757篇 |
1993年 | 10860篇 |
1992年 | 40984篇 |
1991年 | 40358篇 |
1990年 | 39885篇 |
1989年 | 38706篇 |
1988年 | 36108篇 |
1987年 | 35349篇 |
1986年 | 33724篇 |
1985年 | 32134篇 |
1984年 | 23922篇 |
1983年 | 20818篇 |
1982年 | 12377篇 |
1981年 | 10927篇 |
1980年 | 10204篇 |
1979年 | 22635篇 |
1978年 | 15877篇 |
1977年 | 13729篇 |
1976年 | 12970篇 |
1975年 | 14201篇 |
1974年 | 16682篇 |
1973年 | 16076篇 |
1972年 | 15318篇 |
1971年 | 14229篇 |
1970年 | 13214篇 |
1969年 | 12731篇 |
1968年 | 11978篇 |
1967年 | 10478篇 |
Methods: Rats (n = 30) were injected with varying doses (0.625, 2.5, and 10 U) of botulinum toxin into the tibialis muscle. Control animals (n = 9) received an equivalent volume of saline. At 128 days after injection, neuromuscular function, pharmacodynamics of atracurium, and nAChRs were evaluated.
Results: Nerve-evoked tensions, including tetanic tension and muscle mass, were decreased on the toxin-injected side in a dose-dependent manner relative to saline-injected controls as well as the contralateral side. Specific muscle tension and specific tetanic muscle tension (tensions/muscle mass) were not reduced. The ED10 of atracurium was reduced, the ED50 was unchanged, and the ED90 was increased in the highest (10-U) dose of toxin group. The atracurium plasma concentration to maintain a steady state 50% paralysis was significantly reduced in the 10-U toxin group. The nAChR concentrations in the tibialis muscle were significantly increased in a dose-dependent manner in all experimental groups. 相似文献
Methods: With approval, 300 consenting healthy patients, aged 18-50 yr, presenting for elective surgery requiring relaxant general anesthesia with a broad range of agents were studied. Patients were interviewed on emergence and 2-4 h postoperatively. The Bispectral Index was recorded from induction until the first interview. Dream content and form were also assessed.
Results: Dreaming was reported by 22% of patients on emergence. There was no difference between dreamers and nondreamers in median Bispectral Index values during maintenance (37 [23-55] vs. 38 [20-59]; P = 0.68) or the time at Bispectral Index values greater than 60 (0 [0-7] vs. 0 [0-31] min; P = 0.38). Dreamers tended to be younger and male, to have high home dream recall, to receive propofol maintenance or regional anesthesia, and to open their eyes sooner after surgery. Most dreams were similar to dreams of sleep and were pleasant, and the content was unrelated to surgery. 相似文献