全文获取类型
收费全文 | 111篇 |
免费 | 2篇 |
专业分类
耳鼻咽喉 | 5篇 |
儿科学 | 4篇 |
妇产科学 | 2篇 |
基础医学 | 4篇 |
临床医学 | 15篇 |
内科学 | 29篇 |
皮肤病学 | 19篇 |
特种医学 | 10篇 |
外科学 | 11篇 |
综合类 | 3篇 |
预防医学 | 1篇 |
眼科学 | 1篇 |
药学 | 5篇 |
肿瘤学 | 4篇 |
出版年
2021年 | 1篇 |
2020年 | 2篇 |
2019年 | 2篇 |
2018年 | 2篇 |
2016年 | 7篇 |
2015年 | 3篇 |
2014年 | 2篇 |
2013年 | 6篇 |
2012年 | 4篇 |
2011年 | 11篇 |
2010年 | 1篇 |
2009年 | 3篇 |
2008年 | 4篇 |
2007年 | 7篇 |
2006年 | 10篇 |
2005年 | 14篇 |
2004年 | 7篇 |
2003年 | 13篇 |
2002年 | 10篇 |
2001年 | 4篇 |
排序方式: 共有113条查询结果,搜索用时 93 毫秒
61.
Kaya TI Kokturk A Guleryuz A Bagdatoglu C Ikizoglu G 《International journal of dermatology》2002,41(2):119-120
A 13‐year‐old girl was referred to our dermatology outpatient clinic for the treatment of a congenital, circumscribed, hypertrichotic area on the lumbosacral region because it was cosmetically embarrassing. Dermatologic examination revealed a 25 × 15 cm circumscribed hypertrichotic area on the lumbosacral region. Coarse, dark, terminal hairs were observed, but the underlying skin was normal ( Fig. 1 ). The lesion had been present since birth. Her history also revealed back pain, which developed by 3 years of age, and a long history of urinary incontinence. On neurologic examination, no motor weakness or sensory changes were observed. On orthopedic examination, minimal atrophy and 2 cm shortening of the right leg were detected, and the right foot was smaller than the left. There was an accentuation of lumbar lordosis. There was no history of a similar lesion in the family. There was no consanguinity in the relatives.
62.
63.
Elevated C-reactive protein levels and increased cardiovascular risk in patients with obstructive sleep apnea syndrome 总被引:8,自引:0,他引:8
Obstructive sleep apnea syndrome (OSAS) is associated with cardiovascular morbidity and mortality. Inflammatory processes associated with OSAS may contribute to cardiovascular morbidity in these patients. C-reactive protein (CRP) is an important serum marker of inflammation. We tested the hypothesis that patients with OSAS have increased plasma CRP. After 173 male subjects underwent polysomnography, 94 were considered to have OSAS (apnea-hypopnea index (AHI) > 5), 38 cardiovascular disease (CVD), and 56 without CVD. Seventy-nine subjects were considered not to have OSAS (AHI < 5) and from among these 57 patients without CVD were enrolled as control subjects. Serum CRP levels were significantly elevated in the OSAS + CVD group compared to the two other groups (P < 0.05). When we evaluated the association between the serum CRP level and severity of OSAS, CRP levels were positively correlated with AHI in OSAS patients (r = 0.61, P < 0.001) OSAS, as a marker of inflammation and cardiovascular risk, is associated with elevated levels of CRP. According to these results, the link between cardiovascular morbidity and OSAS may be explained by the coexistence of other cardiovascular risk factors such as circulating CRP levels. 相似文献
64.
Ayca Cordan Yazici Sakir Unal Guliz Ikizoglu Aysin Kokturk Kiymet Baz Leyla Cinel Aynur Koca 《Nordisk plastikkirurgisk forening [and] Nordisk klubb for handkirurgi》2006,40(1):54-56
Superficial basal cell carcinomas (BCC) comprise 9% to 11% of BCC, and are commonly found on the trunk or limbs. We report a case of a superficial BCC on the scalp that was misdiagnosed and treated as seborrhoeic dermatitis. Any erythematous plaque-type lesion of long duration must have superficial BCC considered in the differential diagnosis. 相似文献
65.
Clozapine and olanzapine are antipsychotic drugs commonly used to treat schizophrenia and psychosis; however, few studies have investigated their effects on cognitive function using animal models. Thus, the effects of olanzapine and clozapine on memory acquisition, consolidation and retrieval were investigated in naive mice using a modified elevated plus maze (mEPM) task. Olanzapine (0.15 and 0.30 mg/kg) and clozapine (0.5 and 1 mg/kg) were injected intraperitoneally (i.p.) into male Balb-c mice before training, immediately after training or before the second day of the trial. Our results showed that both olanzapine and clozapine disrupted the acquisition of spatial memory. In addition, clozapine impaired the consolidation of spatial memory, while olanzapine had no effect. Furthermore, olanzapine and clozapine significantly disrupted memory retrieval in naive mice. Thus, these results at least suggest that olanzapine can be a superior treatment for schizophrenia compared to clozapine. 相似文献
66.
67.
Oguz Mutlu Esen Gumuslu Guner Ulak Ipek Komsuoglu Celikyurt Furuzan Akar Emine Bektas Tugce Demirtas Hale Maral Kır Mahmut Mert Musul Faruk Erden 《Drug development research》2013,74(3):203-215
Preclinical Research |
68.
Fusun Comert Elif Aktas H. Agah Terzi Canan Kulah Yucel Ustundag Furuzan Kokturk Selim Aydemir 《Diagnostic microbiology and infectious disease》2013
To assess the stability of various sample types and storage conditions for quantitative detectability of hepatitis C virus (HCV) RNA viral loads, we studied serum and EDTA/citrate plasma samples obtained from 10 patients known to be positive for HCV RNA. Samples were subjected to the following conditions: 1) 10 freeze–thaw (FT) cycles, and 2) storage at room temperature for 24, 48, and 72 h. Detection of HCV RNA was performed by COBAS AmpliPrep/COBAS TaqMan HCV. The following conclusions were reached: 1) no significantly different viral loads were observed in different blood compartments; 2) no significantly different viral loads were observed after 24, 48, and 72 h at room temperature; 3) no significantly different viral loads were observed after 10 FT cycles in serum and plasma samples; and 4) HCV RNA is quite stable in serum and plasma (EDTA/citrate) samples. 相似文献
69.
Thrombolytic therapy may reduce the morbidity of pulmonary thromboembolism (PTE) and the risk of recurrent disease. The most important complication of thrombolytic therapy is bleeding. We report a patient with PTE complicated by massive vaginal bleeding due to thrombolytic therapy. 相似文献
70.