全文获取类型
收费全文 | 180106篇 |
免费 | 1280篇 |
国内免费 | 27篇 |
专业分类
耳鼻咽喉 | 1172篇 |
儿科学 | 6725篇 |
妇产科学 | 3111篇 |
基础医学 | 17236篇 |
口腔科学 | 1557篇 |
临床医学 | 12824篇 |
内科学 | 31909篇 |
皮肤病学 | 928篇 |
神经病学 | 16829篇 |
特种医学 | 9073篇 |
外国民族医学 | 3篇 |
外科学 | 29601篇 |
综合类 | 2318篇 |
预防医学 | 18225篇 |
眼科学 | 2828篇 |
药学 | 9726篇 |
中国医学 | 638篇 |
肿瘤学 | 16710篇 |
出版年
2023年 | 34篇 |
2022年 | 66篇 |
2021年 | 138篇 |
2020年 | 90篇 |
2019年 | 151篇 |
2018年 | 22076篇 |
2017年 | 17439篇 |
2016年 | 19583篇 |
2015年 | 1006篇 |
2014年 | 970篇 |
2013年 | 959篇 |
2012年 | 7244篇 |
2011年 | 21315篇 |
2010年 | 18972篇 |
2009年 | 11677篇 |
2008年 | 19746篇 |
2007年 | 21951篇 |
2006年 | 749篇 |
2005年 | 2440篇 |
2004年 | 3608篇 |
2003年 | 4545篇 |
2002年 | 2690篇 |
2001年 | 376篇 |
2000年 | 545篇 |
1999年 | 301篇 |
1998年 | 261篇 |
1997年 | 239篇 |
1996年 | 120篇 |
1995年 | 138篇 |
1994年 | 118篇 |
1993年 | 79篇 |
1992年 | 114篇 |
1991年 | 154篇 |
1990年 | 202篇 |
1989年 | 146篇 |
1988年 | 107篇 |
1987年 | 89篇 |
1986年 | 71篇 |
1985年 | 65篇 |
1984年 | 51篇 |
1983年 | 48篇 |
1982年 | 36篇 |
1980年 | 50篇 |
1979年 | 32篇 |
1974年 | 33篇 |
1970年 | 34篇 |
1969年 | 33篇 |
1938年 | 60篇 |
1932年 | 56篇 |
1930年 | 46篇 |
排序方式: 共有10000条查询结果,搜索用时 17 毫秒
31.
32.
33.
Franck Ceppa Stephane Gidenne Alain Benois Eleonore Fontan Pascal Burnat 《Clinical chemistry and laboratory medicine》2002,40(8):799-801
Human butyrylcholinesterase is the enzyme responsible of mivacurium and succinylcholine metabolism, which may be significantly impaired when mutation Asp70Gly is found in patients. We describe a simple PCR method for the detection of this variant. Thirteen out of sixteen patients tested after prolonged apnea were positive for the presence of this mutation (50.0% homozygotes and 31.3% heterozygotes), suggesting that this test contributes to the explanation of some clinical events and to their prevention in relatives of these patients. 相似文献
34.
Irwin L. Flink 《Brain structure & function》2002,205(3):235-244
35.
36.
37.
38.
A simple tool to evoke physicians' real training needs. 总被引:1,自引:0,他引:1
David Pérol Jean-Pierre Boissel Christiane Broussolle Jean-Charles Cêtre Jean Stagnara Franck Chauvin 《Academic medicine》2002,77(5):407-410
Commonly used methods for identifying the training needs of general practitioners do not enable the real needs felt during interviews with patients during office visits to be detected. In this study, the authors evaluate how physicians' use of a personal-office-visit diary affects the level of specificity of their expressed training needs. In 1999, the authors carried out a controlled intervention trial using a random sample of 1,038 general practitioners from a region of France, randomized to intervention and control groups. The practitioners in the intervention group were asked to identify their training needs using a personal-office-visit diary. The level of specificity for their expressed needs was compared with that of the expressed needs of the practitioners in the control group. The use of the diary was associated with a significantly higher level of specificity in the training needs identified by the general practitioners who participated. Independent of the intervention, practitioners under 40 years of age, those in urban practice, and those who were members of a continuing medical education (CME) association expressed their training needs with higher specificity. The personal-office-visit diary would seem to be a simple, inexpensive, and useful tool for more specifically identifying training needs, which could help establish more appropriate and better-targeted training programs. However, it should be assessed further by those involved in CME for general practitioners. 相似文献
39.
Paul Hochstein Ulrich Glatzel Thomas Schmickal Andreas Wentzensen 《Trauma und Berufskrankheit》2002,4(2):s110-s114
The treatment of deep cartilage defects in load-bearing joints is a problem that still has no satisfactory solution. Full-thickness defects of the articular cartilage rarely heal spontaneously, usually leaving damage that can lead to early arthrosis. Techniques currently available for the treatment of chondral defects include abrasion, drilling, micro-fracturing, transplantation of tissue autografts and allografts, and cell transplantation. Osteochondral autograft transplantation is currently the only surgical cartilage repair technique known to lead to the formation of genuine hyaline articular cartilage and its retention at least in the medium term. The Draenert method, in which a water-cooled diamond bone-cutting system is used, is an effective procedure for resurfacing the joints affected by localised cartilaginous defects, even when there is also severe bone loss. Donor-side morbidity can be kept to a minimum by filling the defect caused by harvesting with a press-fit cylinder of cancellous bone covered with periosteum for protection. 相似文献
40.
Annemieke Smit-van Oosten Winston W. Bakker Harry van Goor 《Transplant international》2002,15(12):602-609
Ischemic injury plays an important role in chronic renal transplant failure (CRTF). Down-regulation of ecto-adenosine triphosphatase (ATPase) in combination with up-regulation of ecto-5'-nucleotidase is a hallmark of ischemic injury. We studied the expression of renal ecto-5'-nucleotidase and ecto-ATPase in experimental renal transplantation. Fisher 344-to-Lewis allografted rats were either treated with an angiotensin-converting enzyme inhibitor (ACEi) or left untreated. Lewis-to-Lewis syngrafted rats served as controls. Untreated allografted rats developed proteinuria, glomerulosclerosis, and mild intimal hyperplasia. ACEi completely prevented focal and segmental glomerulosclerosis (FGS) and proteinuria, but significantly enhanced intimal hyperplasia. Untreated allografted rats revealed marked vascular ecto-5'-nucleotidase activity, which increased with ACEi. Vascular ecto-5'-nucleotidase activity was absent in syngrafted animals. Ecto-5'-nucleotidase activity correlated well with intimal hyperplasia. Glomerular ecto-ATPase expression was significantly reduced in untreated allografted rats compared to syngrafted rats and correlated well with the extent of FGS. ACEi prevented reduction in glomerular ecto-ATPase. We found de-novo expression of ecto-5'-nucleotidase at sites of renal intimal hyperplasia. Glomerular ecto-ATPase expression was markedly reduced in allografted rats and was prevented by ACEi. These enzyme expression patterns suggest local ischemic damage in experimental CRTF. 相似文献