全文获取类型
收费全文 | 8525篇 |
免费 | 783篇 |
国内免费 | 30篇 |
专业分类
耳鼻咽喉 | 104篇 |
儿科学 | 384篇 |
妇产科学 | 162篇 |
基础医学 | 849篇 |
口腔科学 | 157篇 |
临床医学 | 868篇 |
内科学 | 2238篇 |
皮肤病学 | 463篇 |
神经病学 | 867篇 |
特种医学 | 263篇 |
外科学 | 1074篇 |
综合类 | 193篇 |
现状与发展 | 20篇 |
一般理论 | 11篇 |
预防医学 | 739篇 |
眼科学 | 153篇 |
药学 | 360篇 |
中国医学 | 5篇 |
肿瘤学 | 428篇 |
出版年
2021年 | 121篇 |
2020年 | 78篇 |
2019年 | 107篇 |
2018年 | 175篇 |
2017年 | 130篇 |
2016年 | 147篇 |
2015年 | 170篇 |
2014年 | 210篇 |
2013年 | 273篇 |
2012年 | 332篇 |
2011年 | 353篇 |
2010年 | 242篇 |
2009年 | 240篇 |
2008年 | 346篇 |
2007年 | 352篇 |
2006年 | 338篇 |
2005年 | 321篇 |
2004年 | 308篇 |
2003年 | 264篇 |
2002年 | 261篇 |
2001年 | 262篇 |
2000年 | 289篇 |
1999年 | 259篇 |
1998年 | 96篇 |
1997年 | 105篇 |
1996年 | 99篇 |
1995年 | 91篇 |
1994年 | 82篇 |
1993年 | 79篇 |
1992年 | 180篇 |
1991年 | 177篇 |
1990年 | 132篇 |
1989年 | 172篇 |
1988年 | 158篇 |
1987年 | 165篇 |
1986年 | 172篇 |
1985年 | 171篇 |
1984年 | 134篇 |
1983年 | 127篇 |
1982年 | 96篇 |
1981年 | 68篇 |
1979年 | 114篇 |
1978年 | 104篇 |
1977年 | 78篇 |
1976年 | 83篇 |
1975年 | 98篇 |
1974年 | 94篇 |
1973年 | 94篇 |
1971年 | 83篇 |
1969年 | 76篇 |
排序方式: 共有9338条查询结果,搜索用时 78 毫秒
51.
Z A Arlin T Ahmed A Mittelman E Feldman R Mehta P Weinstein E Rieber P Sullivan P Baskind 《Journal of clinical oncology》1987,5(3):371-375
Amsacrine and high-dose cytarabine (HiDAc), when administered as single agents, are effective treatment of acute leukemia. When used in combination, a high remission rate is also possible. We treated 47 patients with acute myelogenous leukemia (AML), acute lymphoblastic leukemia (ALL), and blastic phase of chronic myelogenous leukemia (CML) with a combination of amsacrine and HiDAc. The patients received amsacrine 200 mg/m2 daily for three days and, concurrently, HiDAc 3 g/m2 over three hours once daily for five days. Of 20 evaluable patients with AML in relapse, there were 12 remissions; of seven additional patients with primary refractory AML, there were two remissions, and of 12 patients with ALL in relapse, there were eight remissions. The three patients with blastic phase CML and the three patients with biphenotypic leukemia did not respond. Nausea, vomiting, stomatitis, hepatic dysfunction, and diarrhea were common, but cutaneous, conjunctival, and significant cerebellar and cerebral side effects were absent. We conclude that this regimen is highly effective therapy for AML and ALL and is also safe, eliminating the major toxicities encountered with HiDAc. 相似文献
52.
Otoplasty is a common cosmetic surgical procedure. Various techniques have been described through the years, many of these addressing only specific aspects of the deformity rather than overall correction of the multiple defects that often occur. To achieve optimal results, an understanding of the embryology of the external ear and an appreciation of the development of otoplasty techniques are useful. Current surgical concepts are emphasized and the authors' graduated approach to otoplasty is presented. Thirty-five cases over a four-year period are reviewed. All achieved a satisfactory cosmetic result; there were 5 complications, 3 being due to Mustarde suture pull-away. Two of these required revision, and revision was also required in another patient who developed a hypertrophic scar. The remaining complication was a minor suture granuloma. 相似文献
53.
54.
55.
M. C. Miller R. C. Byrd N. Ensslin W. C. Feldman M. S. Krick T. H. Prettyman P. A. Russo 《Applied radiation and isotopes》1997,48(10-12)
Monte Carlo simulations were carried out to simulate the response of a boron-loaded plastic scintillator array. These detectors offer potential advantages compared to moderated 3He systems because of their fast response and high efficiency. Tallies were made of neutron capture probability as a function of time and the results were coupled to assay variance estimates to evaluate detector performance. Orders-of-magnitude reductions in count time relative to a 50% efficient thermal counter are possible, in principle, for high (α,n) samples. 相似文献
56.
57.
58.
59.
The computerized database system described was initially developed in 1986 to facilitate analysis of retrospective head and neck cancer data from the Royal Adelaide Hospital Department of Otolaryngology. This has now been expanded to become an on-going patient information management system. It is based on the dBase-III-Plus database package and is implemented on an IBM XT compatible computer. The system was designed to be used by staff without specialist computer skills and is therefore largely “menu-driven.” The main functions include patient record creation, update, and retrieval, and the production of reports including graphical presentations. There is also a powerful but easy to use query facility. The system has already provided much useful epidemiological material but is now beginning to fulfill an even more important role in patient follow-up and in assisting evaluation of alternative treatment protocols. 相似文献
60.
Nodular glomerulopathy associated with nonamyloidotic kappa light chain deposits and excess immunoglobulin light chain synthesis 总被引:6,自引:3,他引:6
下载免费PDF全文
![点击此处可从《The American journal of pathology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
G R Gallo H D Feiner L A Katz G M Feldman E B Correa J V Chuba J N Buxbaum 《The American journal of pathology》1980,99(3):621-644
A nodular glomerulopathy characterized by mesangial deposits of monoclonal kappa light chains was detected by immunofluorescence in a renal biopsy from a patient with proteinuria and hypertension. These nodules lacked the tinctorial and morphologic features of amyloid. Ultrastructurally, the nodules contained electron-dense granular deposits as well as fibrils in parallel arrangement. The fibrils measured 110-140 A in diameter. They were consistent in size with amyloid fibrils. However, they differed in lacking the randomly oriented network of typical amyloid fibrils and more closely resembled fibrils intrinsic to mesangial matrix. The patient had no bone marrow or X-ray evidence of myeloma and no evidence of free monoclonal light chains in serum or concentrated urines. Biosynthetic studies of the patient's bone marrow cells demonstrated unbalanced immunoglobulin synthesis with excess production of monoclonal kappa light chains. These observations suggest that the observed glomerulopathy results from direct deposition of monoclonal light chains. Deposits with kappa light chain determinants have been found in 7 other patients with similar nodular glomerulopathies, 4 of whom had diagnosed clinical myeloma. The lesion of nonamyloidotic nodular glomerulopathy previously described in 19 patients, nor examined by immunopathologic techniques or not shown to contain light chain determinants, may have a similar pathogenesis. 相似文献