全文获取类型
收费全文 | 739篇 |
免费 | 43篇 |
国内免费 | 1篇 |
专业分类
耳鼻咽喉 | 4篇 |
儿科学 | 33篇 |
妇产科学 | 8篇 |
基础医学 | 56篇 |
口腔科学 | 8篇 |
临床医学 | 83篇 |
内科学 | 317篇 |
皮肤病学 | 4篇 |
神经病学 | 17篇 |
特种医学 | 37篇 |
外科学 | 67篇 |
综合类 | 2篇 |
预防医学 | 19篇 |
眼科学 | 1篇 |
药学 | 40篇 |
中国医学 | 1篇 |
肿瘤学 | 86篇 |
出版年
2023年 | 5篇 |
2021年 | 19篇 |
2020年 | 7篇 |
2019年 | 10篇 |
2018年 | 14篇 |
2017年 | 9篇 |
2016年 | 8篇 |
2015年 | 17篇 |
2014年 | 21篇 |
2013年 | 21篇 |
2012年 | 27篇 |
2011年 | 28篇 |
2010年 | 20篇 |
2009年 | 17篇 |
2008年 | 32篇 |
2007年 | 28篇 |
2006年 | 28篇 |
2005年 | 36篇 |
2004年 | 20篇 |
2003年 | 21篇 |
2002年 | 16篇 |
2001年 | 21篇 |
2000年 | 26篇 |
1999年 | 18篇 |
1998年 | 9篇 |
1997年 | 11篇 |
1996年 | 8篇 |
1995年 | 11篇 |
1994年 | 7篇 |
1993年 | 8篇 |
1992年 | 33篇 |
1991年 | 25篇 |
1990年 | 18篇 |
1989年 | 27篇 |
1988年 | 24篇 |
1987年 | 20篇 |
1986年 | 10篇 |
1985年 | 19篇 |
1984年 | 16篇 |
1983年 | 7篇 |
1982年 | 5篇 |
1981年 | 7篇 |
1980年 | 3篇 |
1979年 | 7篇 |
1978年 | 4篇 |
1977年 | 5篇 |
1976年 | 5篇 |
1975年 | 5篇 |
1974年 | 5篇 |
1966年 | 3篇 |
排序方式: 共有783条查询结果,搜索用时 0 毫秒
781.
Joanne M. Carson Sebastiano Barbieri Evan Cunningham Eric Mao Marc van der Valk Jürgen K. Rockstroh Margaret Hellard Arthur Kim Sanjay Bhagani Jordan J. Feld Ed Gane Maria C. Thurnheer Julie Bruneau Elise Tu Gregory J. Dore Gail V. Matthews Marianne Martinello the REACT study group 《Journal of the International AIDS Society》2023,26(9):e26168
Introduction
Exploration of sexual and drug use behaviours following treatment for recent hepatitis C virus (HCV) is limited. This analysis modelled behavioural trajectories following treatment for recent HCV and assessed reinfection.Methods
Participants treated for recent HCV in an international trial (enrolled 2017–2019) were followed at 3-monthly intervals for up to 2 years to assess longitudinal behaviours. Population-averaged changes were assessed using generalized estimating equations. Distinct behavioural trajectories were identified using group-based trajectory modelling. HCV reinfection incidence was calculated using person-years (PY) of observation.Results
During the follow-up of 212 participants (84% gay and bisexual men [GBM]; 69% HIV; 26% current injecting drug use [IDU]), behavioural trajectories for IDU and stimulant use (past month) did not change. However, population-averaged decreases in the likelihood of daily IDU (adjusted odds ratio [AOR] 0.83; 95% CI 0.72, 0.95) and opioid use (AOR 0.84; 95% CI 0.75, 0.93) were observed. Among GBM, behavioural trajectories for chemsex did not change. Population-averaged decreases in condomless anal intercourse with casual male partners (CAI-CMP) (AOR 0.95; 95% CI 0.90, 0.99) and group-sex (AOR 0.86; 95% CI 0.80, 0.93) were observed, but masked distinct trajectories. While a proportion had a decreased probability of CAI-CMP (23%) and group-sex (59%) post-treatment, a substantial proportion retained a high probability of these behaviours. High HCV reinfection incidence was observed for the sustained high probability IDU (33.0/100 PY; 95% CI 17.7, 61.3) and chemsex (23.3/100 PY; 95% CI 14.5, 37.5) trajectories.Conclusions
Limited sexual and drug use behavioural change was observed following treatment for recent HCV, supporting access to surveillance and (re)treatment. 相似文献782.
Atul Verma MD FRCPC Gregory K. Feld MD James L. Cox MD Thomas A. Dewland MD Alexei Babkin PhD Tom De Potter MD Narayan Raju DVM PhD Michel Haissaguerre MD 《Journal of cardiovascular electrophysiology》2023,34(10):2124-2133
Background
Combining pulsed field ablation (PFA) with ultra-low temperature cryoablation (ULTC) represents a novel energy source which may create more transmural cardiac lesions. We sought to assess the feasibility of lesions created by combined cryoablation and pulsed field ablation (PFCA) versus PFA alone.Methods
Ablations were performed using a custom PFA generator, ULTC console, and an ablation catheter with insertable stylets. PFA was delivered in a biphasic, bipolar train. PFCA precooled the tissue for 30 s followed by a concurrent PFA train. Benchtop testing using Schlieren imaging and microbubble volume assessment were used to compare PFA and PFCA. PFA and PFCA lesions using pre-optimized and optimized ablation protocols were studied in 6 swine. Pre and post-ECGs were recorded for each ablation and a gross necropsy was performed at 14 days.Results
Consistent with benchtop comparisons of heat and microbubble generation, PFA deliveries in the animals were accompanied by muscle contractions and significant microbubbles (Grade 2–3) visible on intracardiac echo while neither occurred during PFCA at higher voltage levels. Both PFA and PFCA acutely eliminated or highly attenuated (>80%) local atrial electrograms. Histology of PFA and PFCA lesions indicated depth up to 6–7 mm and nearly all lesions were transmural. Optimized PFCA produced wider cavotricuspid isthmus lesions with evidence of tissue selectivity.Conclusion
A novel technology combining PFA and ULTC into one energy source demonstrated in-vivo feasibility for PFCA ablation. PFCA had a more favorable thermal profile and did not produce muscle contraction or microbubbles while extending lesion depth beyond cryoablation. 相似文献783.
William W. L. Wong Josephine Wong Karen E. Bremner Yasmin Saeed Kate Mason Arcturus Phoon Valérie Martel-Laferrière Julie Bruneau Jordan J. Feld Zeny Feng Elizabeth Baguley Samuel S. Lee Jeff Powis Murray D. Krahn 《Liver international》2023,43(4):805-818