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31.
Hasan Fatih ?ay Ilhan Sezer Mehmet Z. Firat Cahit Ka?ar 《Rheumatology international》2011,31(3):377-385
It is believed that there is an association between the weather and rheumatic symptoms. We aimed to investigate what kind
of association is present and what are the factors which determine the nature of this association. Fifty-six subjects with
rheumatic disease (31 RA, 15 SpA, 10 OA) who live in Antalya were followed between December 2005 and July 2006. Patients were
asked to fill diaries which contain questions regarding the symptoms of their rheumatic diseases everyday. In every monthly
visit, disease activity measurement, laboratory assessment and Beck depression inventory assessment were recorded. The symptomatic
and psychological measurements were matched with the meteorological data of Antalya Regional Directorate of Meteorological
Service of Turkish State. Correlation of symptoms with weather variables was investigated. Contributory effect of weather
and of psychologic factors on symptom scores were evaluated by stepwise multiple regression analysis. Eighty-four percent
of subjects belive in an association between weather and rheumatism, while 57% claimed to have ability to forecast weather.
The maximum correlation coefficient between weather and arthritis symptoms was −0.451 and the maximum contribution of weather
on symptoms was 17.1%. Arthritis symptoms were significantly contributed by Beck depression score. The belief about presence
of weather–arthritis association was found to be stronger than its statistical power. Our results did not prove or rule out
the presence of weather–rheumatism association. As long as the scientific attempts result in failure, the intuitive support
in favour of the presence of weather–arthritis association will go on forever. 相似文献
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Jeremy Michals Schraw Yong Quan Dong Mehmet Fatih Okcu Michael E. Scheurer Michele R. Forman 《Cancer causes & control : CCC》2014,25(1):73-80
Milk formula feeding can elevate insulin-like growth factor-1 levels, possibly impacting leukemogenesis. The intent of the current study is to examine the associations between infant feeding practices and age at introduction of solids on risk of childhood acute lymphoblastic leukemia (ALL). Incident cases of infant and childhood (aged ≤14 years) ALL (n = 142) were enrolled in a case–control study. Cases were frequency matched on age, sex, race, and ethnicity to two sets of controls (n = 284 total). Multivariable logistic regression was used to determine the association between infant feeding practices and age at the introduction of solids and the odds ratio of ALL. In adjusted multivariable analyses, each additional month of formula feeding was associated with a 1.17 (1.09–1.25) odds ratio; each additional month of age at introduction of solids was associated with a 1.18 (1.07–1.30) odds ratio. In this study, longer duration of formula feeding and later age at the introduction of solid foods were independently associated with increased risk of ALL. Additional studies are needed to address the factors influencing duration of formula feeding and delayed introduction of solids. The results support the potential role of energy balance in early life as a contributor to risk for pediatric acute lymphoblastic leukemia. 相似文献
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Ergün Seyfeli Mehmet Duru Güven Kuvandik Hasan Kaya Fatih Yal?in 《Anadolu kardiyoloji dergisi》2006,6(2):126-129
OBJECTIVE: Increased QTc dispersion is a predictor for ventricular arrhythmias. The aim of this study was to investigate whether QTc dispersion decreases after weight loss program with diet and medical treatment. METHODS: Total 30 (24 women and 6 men, mean age: 44+/-8 years) obese subjects who lost at least 10% of their original weight after 12 week weight loss program were included in present study. Obesity was defined as > or =30 kg/m(2) of body mass index (BMI). Normal weight was defined as < or = 25 kg/m(2) of BMI. RESULTS: After 12 week weight loss program, BMI decreased from 42+/-5 kg/m(2) to 36+/-4 kg/m(2) (p<0.001) and mean weight of obese subjects decreased from 110+/-17 kg to 95+/-15 kg (p<0.001). The mean amount of weight loss was 14.5+/-5.0 kg (range 9-32 kg). The average percent of weight loss was 13% (10.0%-20.3%). Maximum QTc interval (from 446+/-19 ms to 433+/-27 ms, p=0.024) and QTc dispersion (from 66+/-18 ms to 52+/-25 ms, p=0.024) significantly decreased after weight loss program. A statistically significant correlation was found between decrease in level of QTc dispersion and amount of weight loss (r=0.487, p=0.007). CONCLUSION: Substantial weight loss in obese subjects is accompanied by significantly decreased QTc dispersion. The degree of QTc dispersion reduction is associated with amount of weight loss. 相似文献
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Calkavur T Yagdi T Apaydin A Islamoglu F Posacioglu H Durmaz I Ozbaran M 《The Journal of heart valve disease》2002,11(2):263-269
BACKGROUND AND AIM OF THE STUDY: Although over 20,000 Edwards-Duromedics valves were implanted worldwide between 1982 and May 1988, use of the valve was voluntarily suspended by the manufacturer in May 1988 on the basis of reported leaflet escapes. In 1990, a modified version was introduced to the market, the Edwards-Tekna. The study aim was to evaluate the short-term outcome with this revised valve. METHODS: Between 1994 and 1998, 137 patients (67 males, 70 females; mean age 36.3+/-9.1 years) underwent heart valve replacement with the Edwards-Tekna prosthesis. Among these patients, 72 had isolated mitral valve replacement, 59 isolated aortic valve replacement, and six double-valve replacement. RESULTS: Early hospital mortality was 0.72% (n = 1). Follow up was 95% complete (129/136 patients discharged from hospital). Mean follow up was 24.9+/-10.5 months (range: 2 to 48 months); total follow up was 282.9 patient-years (pt-yr). Actuarial freedom from complications at two-year follow up and linearized incidence (%/pt-yr) of these events were: late mortality 87.8+/-8.5% (1.77%/pt-yr); thromboembolism 89.8+/-4.9% (2.12%/pt-yr); anticoagulation-related bleeding 97.8+/-1.5% (0.71%/pt-yr); prosthetic valve endocarditis 99.1+/-0.9% (0.35%/pt-yr); valve-related mortality 98.2+/-1.2% (0.71%/pt-yr); and valve-related morbidity and mortality 85.0+/-5.0% (4.24%/pt-yr). There was no structural valve failure such as leaflet escape in this series. Clinically significant hemolysis was not encountered (mean postoperative plasma LDH level 345+/-124 IU/l). Preoperatively, 69% of patients were in NYHA classes III/IV; at two years postoperatively 90% of survivors were in classes I/II. CONCLUSION: The Edwards-Tekna mechanical valve prosthesis has shown excellent overall clinical performance in the short term, though long-term data are needed to confirm its durability. 相似文献
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Kar Fatih Hacioglu Ceyhan Kar Ezgi Donmez Dilek Burukoglu Kanbak Güngör 《Metabolic brain disease》2022,37(5):1387-1399
Metabolic Brain Disease - The gut microbiota influences brain development and functioning through the gut-brain axis. This is first study regulate maternal gut microbiota and fetal neurodevelopment... 相似文献
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