全文获取类型
收费全文 | 82206篇 |
免费 | 7081篇 |
国内免费 | 3504篇 |
专业分类
耳鼻咽喉 | 655篇 |
儿科学 | 1539篇 |
妇产科学 | 1500篇 |
基础医学 | 10348篇 |
口腔科学 | 1479篇 |
临床医学 | 9217篇 |
内科学 | 14057篇 |
皮肤病学 | 1193篇 |
神经病学 | 5141篇 |
特种医学 | 3037篇 |
外国民族医学 | 34篇 |
外科学 | 9258篇 |
综合类 | 9182篇 |
现状与发展 | 15篇 |
一般理论 | 43篇 |
预防医学 | 6198篇 |
眼科学 | 1846篇 |
药学 | 7750篇 |
52篇 | |
中国医学 | 3116篇 |
肿瘤学 | 7131篇 |
出版年
2024年 | 201篇 |
2023年 | 1029篇 |
2022年 | 2421篇 |
2021年 | 3491篇 |
2020年 | 2486篇 |
2019年 | 2494篇 |
2018年 | 2713篇 |
2017年 | 2332篇 |
2016年 | 2398篇 |
2015年 | 3181篇 |
2014年 | 3989篇 |
2013年 | 4348篇 |
2012年 | 6117篇 |
2011年 | 6385篇 |
2010年 | 4011篇 |
2009年 | 3353篇 |
2008年 | 4828篇 |
2007年 | 4827篇 |
2006年 | 4457篇 |
2005年 | 4191篇 |
2004年 | 3476篇 |
2003年 | 3316篇 |
2002年 | 2963篇 |
2001年 | 1797篇 |
2000年 | 1678篇 |
1999年 | 1558篇 |
1998年 | 956篇 |
1997年 | 932篇 |
1996年 | 752篇 |
1995年 | 653篇 |
1994年 | 566篇 |
1993年 | 413篇 |
1992年 | 560篇 |
1991年 | 479篇 |
1990年 | 438篇 |
1989年 | 391篇 |
1988年 | 300篇 |
1987年 | 303篇 |
1986年 | 250篇 |
1985年 | 214篇 |
1984年 | 171篇 |
1983年 | 130篇 |
1982年 | 130篇 |
1981年 | 126篇 |
1980年 | 84篇 |
1979年 | 109篇 |
1978年 | 71篇 |
1976年 | 58篇 |
1974年 | 69篇 |
1973年 | 61篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
31.
Julie A. Schmidt Georgina K. Fensom Sabina Rinaldi Augustin Scalbert Paul N. Appleby David Achaintre Audrey Gicquiau Marc J. Gunter Pietro Ferrari Rudolf Kaaks Tilman Kühn Heiner Boeing Antonia Trichopoulou Anna Karakatsani Eleni Peppa Domenico Palli Sabina Sieri Rosario Tumino Bas Bueno-de-Mesquita Antonio Agudo Maria-Jose Sánchez María-Dolores Chirlaque Eva Ardanaz Nerea Larrañaga Aurora Perez-Cornago Nada Assi Elio Riboli Konstantinos K. Tsilidis Timothy J. Key Ruth C. Travis 《International journal of cancer. Journal international du cancer》2020,146(3):720-730
Metabolomics may reveal novel insights into the etiology of prostate cancer, for which few risk factors are established. We investigated the association between patterns in baseline plasma metabolite profile and subsequent prostate cancer risk, using data from 3,057 matched case–control sets from the European Prospective Investigation into Cancer and Nutrition (EPIC). We measured 119 metabolite concentrations in plasma samples, collected on average 9.4 years before diagnosis, by mass spectrometry (AbsoluteIDQ p180 Kit, Biocrates Life Sciences AG). Metabolite patterns were identified using treelet transform, a statistical method for identification of groups of correlated metabolites. Associations of metabolite patterns with prostate cancer risk (OR1SD) were estimated by conditional logistic regression. Supplementary analyses were conducted for metabolite patterns derived using principal component analysis and for individual metabolites. Men with metabolite profiles characterized by higher concentrations of either phosphatidylcholines or hydroxysphingomyelins (OR1SD = 0.77, 95% confidence interval 0.66–0.89), acylcarnitines C18:1 and C18:2, glutamate, ornithine and taurine (OR1SD = 0.72, 0.57–0.90), or lysophosphatidylcholines (OR1SD = 0.81, 0.69–0.95) had lower risk of advanced stage prostate cancer at diagnosis, with no evidence of heterogeneity by follow-up time. Similar associations were observed for the two former patterns with aggressive disease risk (the more aggressive subset of advanced stage), while the latter pattern was inversely related to risk of prostate cancer death (OR1SD = 0.77, 0.61–0.96). No associations were observed for prostate cancer overall or less aggressive tumor subtypes. In conclusion, metabolite patterns may be related to lower risk of more aggressive prostate tumors and prostate cancer death, and might be relevant to etiology of advanced stage prostate cancer. 相似文献
32.
OBJECTIVES: To assess the effectiveness and safety of additional bedtime H2‐receptor antagonists (H2RAs) in suppressing nocturnal gastric acid breakthrough (NAB) via a systematic review. METHODS: Eligible trials were identified by searching the Cochrane Central Register of Controlled Trials (CENTRAL) (Cochrane Library Issue 2, 2004), MEDLINE (January 1966–June 2004), EMBASE (January 1980–June 2004) and CINAHL (January 1982–June 2004). Additional hand‐searching was conducted on the proceedings of correlated conferences, eight important Chinese journals and references of all included trials. All randomized controlled trials evaluating H2RAs for the control of NAB were eligible for inclusion. The systematic review was conducted using methods recommended by The Cochrane Collaboration. RESULTS: Only two randomized crossover studies, comprising 32 participants, met the inclusion criteria. Because the design, dosage and duration of the treatments were different between the studies, it was not possible to conduct meta‐analysis. There were no consistent conclusions found between the two included studies in evaluating H2RAs for the control of NAB. CONCLUSIONS: No implications for practice at this stage can be concluded. Appropriately designed large‐scale randomized controlled trials with long‐term follow up are needed to determine the effects of additional bedtime H2RAs in suppressing NAB. 相似文献
33.
Meng Qingyue Li Renzhong Cheng Gang 《中国防痨杂志》2003,25(Z1):22-23
INTRODUCTION: The financial responsibility in health sector was decentralizedfrom central and provincial governments to county and township governments. It was argued that a decentralized system without effective transfer payment mechanism has pushed the poverty area to more disadvantaged positions in economic development in general. 相似文献
34.
Mei-Ju Chen Ching-Yu Cheng Yen-Cheng Chen Ching-Kuang Chou Wen-Ming Hsu 《Journal of ocular pharmacology and therapeutics》2006,22(3):188-193
PURPOSE: The aim of this study was to investigate the effects of bimatoprost 0.03% on ocular hemodynamics in patients with normal tension glaucoma (NTG). METHODS: Twenty-two (22) patients with NTG were consecutively recruited. After basic eye examination and diurnal intraocular pressure (IOP) measurement, color Doppler imaging was used to measure the peak systolic and end diastolic velocities and resistive index of the central retinal, lateral posterior ciliary, and medial posterior ciliary arteries. Patients received bimatoprost 0.03% for 4 weeks, and these measurements were then repeated. The worse eye of each NTG patient was used in the statistical analysis. RESULTS: Bimatoprost 0.03% significantly reduced mean IOP from 15.1 +/- 3.8 mmHg at baseline to 12.0 +/- 2.9 mmHg after treatment in our sample of NTG patients (P < 0.001). No significant changes in blood velocities or resistance indices were observed in the retrobulbar vessels after the 4-week treatment. CONCLUSIONS: Topical bimatoprost 0.03% significantly reduced IOP in our NTG patients without causing significant hemodynamic changes in the retrobulbar vessels. 相似文献
35.
外科学教学中的审美教育 总被引:1,自引:0,他引:1
医学审美教育是医学生全面素质教育不可分割的组成部分,笔者结合长期外科教学实践,阐述了在外科学教学中运用医学美学原理对外科学的美进行开发和挖掘,使医学生在熟练掌握外科学基本理论和基本技能的同时,潜移默化地接受美的教育,美的熏陶,更能激发他们对外科学的热爱和兴趣,达到全面提高医学生整体素质的目的。 相似文献
36.
Pulmonary Lophomonas blattarum infection in patients with kidney allograft transplantation 总被引:3,自引:0,他引:3
Yong Wang Zheng Tang Shuming Ji Zhen Zhang Jinsong Chen Zhen Cheng Dongrui Cheng Zhihong Liu Leishi Li 《Transplant international》2006,19(12):1006-1013
The aim of the study was to analyse the clinical manifestation and management of pulmonary Lophomonas blattarum infection in four allograft transplantation recipients retrospectively. Four patients with pulmonary L. blattarum infection were diagnosed by using Fiberoptic bronchoscopy (FOB) and bronchoalveolar lavage (BAL) examination. Their clinical manifestation and management are summarized. Four cases of pulmonary L. blattarum were found during the period from the second month to the third month after transplantation. Concurring infection by other pathogens was found in three of them. Common initial symptoms included fever (>38 degrees C) without cough and breathlessness. Lower lobe shadowing could be found on chest X-ray. Body temperature decreased to the normal range in three patients and to 37.5 degrees C in the other one, after intravenous injection of metronidazole and tapering immunosuppressant. Radiological examination confirmed improved health condition of the patients afterwards. Two patients received repeated FOB and only dead L. blattarum was found. Pulmonary L. blattarum infection in allograft transplant recipients carry relatively obscure initial symptoms. Possible L. blattarum infection needs to be screened in post-transplantation pulmonary infection patients with similar symptoms, especially in those who respond poorly to anti-infection treatment. Microscopic examination of BAL fluid can help to identify pulmonary L. blattarum infection and metronidazole is an ideal treatment choice. 相似文献
37.
成虹 《世界核心医学期刊文摘》2006,2(3):59-62
颈部食管的异位胃黏膜:是否参与了后壁喉炎患咽喉部反流的发病机制;结肠直肠癌手术联合放疗与单纯手术治疗后的大便失禁患,在盆底运动/生物反馈训练的短期和远期疗效方面的比较:一项临床、功能性及内镜/超声内镜检查的前瞻性对照研究。 相似文献
38.
分析近年来国内高校教育形式的变化,肯定扎实学生基础、培养创新型人才的重要性,结合多年来在工科物理教改中的探索经验和初步成果,提出了深化工科物理教学改革、培养创新型人才的思路和实现途径。 相似文献
39.
40.
医源性胆管狭窄X线表现 总被引:1,自引:0,他引:1
本文报道了13例医源性胆管狭窄,分析其影像表现。特点为:环形狭窄;线样狭窄,包括规则的和不规则的线样狭窄;闭塞性狭窄;胆管闭塞和胆管中断分离。ERCT和PCT对狭窄的形态,位置及长度显示优于CT和US。 相似文献