全文获取类型
收费全文 | 9177篇 |
免费 | 889篇 |
国内免费 | 184篇 |
专业分类
耳鼻咽喉 | 69篇 |
儿科学 | 331篇 |
妇产科学 | 173篇 |
基础医学 | 709篇 |
口腔科学 | 122篇 |
临床医学 | 1622篇 |
内科学 | 2242篇 |
皮肤病学 | 159篇 |
神经病学 | 593篇 |
特种医学 | 305篇 |
外国民族医学 | 1篇 |
外科学 | 2138篇 |
综合类 | 26篇 |
一般理论 | 3篇 |
预防医学 | 579篇 |
眼科学 | 384篇 |
药学 | 253篇 |
中国医学 | 13篇 |
肿瘤学 | 528篇 |
出版年
2023年 | 136篇 |
2022年 | 86篇 |
2021年 | 175篇 |
2020年 | 159篇 |
2019年 | 140篇 |
2018年 | 226篇 |
2017年 | 250篇 |
2016年 | 252篇 |
2015年 | 227篇 |
2014年 | 349篇 |
2013年 | 447篇 |
2012年 | 333篇 |
2011年 | 400篇 |
2010年 | 350篇 |
2009年 | 464篇 |
2008年 | 339篇 |
2007年 | 270篇 |
2006年 | 287篇 |
2005年 | 270篇 |
2004年 | 204篇 |
2003年 | 212篇 |
2002年 | 224篇 |
2001年 | 167篇 |
2000年 | 110篇 |
1999年 | 183篇 |
1998年 | 222篇 |
1997年 | 252篇 |
1996年 | 334篇 |
1995年 | 285篇 |
1994年 | 218篇 |
1993年 | 140篇 |
1992年 | 169篇 |
1991年 | 180篇 |
1990年 | 120篇 |
1989年 | 193篇 |
1988年 | 151篇 |
1987年 | 114篇 |
1986年 | 138篇 |
1985年 | 113篇 |
1984年 | 115篇 |
1983年 | 90篇 |
1982年 | 85篇 |
1981年 | 75篇 |
1980年 | 84篇 |
1978年 | 71篇 |
1977年 | 58篇 |
1976年 | 57篇 |
1975年 | 56篇 |
1964年 | 52篇 |
1963年 | 48篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
11.
12.
Patients'attitudes to rectal drug administration 总被引:2,自引:0,他引:2
One hundred adult patients attending for day case surgery were surveyed by anonymous questionnaire in order to determine their attitudes to rectal drug administration. Fifty four patients did not want an analgesic drug (diclofenac sodium) administered rectally whilst under anaesthesia, all preferring to take it orally if available. Ninety eight patients thought that drugs administered per rectum should always be discussed with them beforehand and a few had very strong feelings about this route of administration. We suggest that prescribers of rectal diclofenac should always discuss it with patients pre-operatively. Whilst many are happy to have suppositories, some young patients are sensitive about this and prefer to take such medication by mouth. 相似文献
13.
Strains of Saccharomyces cerevisiae FL200 capable of growing on a solid medium containing a mixture of polyene macrolide antibiotics (nystatin, 40 micrograms/ml, amphotericin B, 40 micrograms/ml, pimaricin, 150 micrograms/ml and RP9971 antibiotic, 10 micrograms/ml) have been isolated after successive selection steps. The mutant strains, PR13 and PRC24, are 10 to 100 times more resistant than the polyene macrolide antibiotics. When 4% Tween 80 is added to the medium, resistance to these antifungal drugs is further increased. In addition, strain PRC24, derived from strain PR13, is resistant to a non-polyene macrolide antifungal antibiotic, cycloheximide. In contrast, PR13 and PRC24 are both highly susceptible to a large range of compounds, including non-polyenic antifungal, antitumor and antibacterial agents. These particular characteristics make these strains useful for the rapid detection of antifungal compounds of the polyene macrolide and cycloheximide types, as well as for the recognition of antimitotic substances. 相似文献
14.
P. E. Wallemacq Raymond Reding Etienne M. Sokal Jean Ville de Goyet Stéphane Clement de Clety Véronique Van Leeuw Marc De Backer Jean-Bernard Otte 《Transplant international》1997,10(6):466-470
Pediatric liver transplant recipients constitute a population characterized by a particularly unpredictable and poor bioavailability
of cyclosporin (CyA). Even though several adult studies show that the new oral formulation of CyA, Neoral (NEO), produces
better bioavailability and blood level predictability, few data describe its pharmacokinetics in children. We performed a
complete analysis of the pharmacokinetics of NEO in ten small children after primary liver transplantation. Three pharmacokinetic
profiles were set up with data obtained from tests taken during i. v. administration of CyA, after the first oral NEO dose,
and after the last NEO dose before discharge from the hospital. The mean half-lives obtained were 8.1, 7.7, and 6.9 h, respectively,
and the bioavailabilities were 22 % and 21 % for the first and last NEO doses. A large interpatient variability was observed.
This was due, in part, to episodes of diarrhea that interfered with the pharmacokinetic evaluation and, in part, to the variability
of post-transplant hepatic function. There was a good correlation between CyA trough levels and their related AUCs for both
NEO profiles (r = 0.93 and r = 0.74, respectively). We conclude that, even though the pediatric OLT population remains more unpredictable than that of
adults, NEO has a relatively rapid half-life and a remarkably improved bioavailability.
Received: 29 November 1996 Received after revision: 10 April 1997 Accepted: 15 May 1997 相似文献
15.
Barry J. Nicholls MB ChB FFARCS Bruce F. Cullen MD 《Journal of clinical anesthesia》1988,1(2):115-129
Trauma is the leading cause of death for persons aged 1 to 38 years. Successful management is facilitated by prehospital endotracheal intubation, transport to regional trauma centers, rapid resuscitation by an on-site team of trained physicians, timely operative intervention, and provision of care by well-prepared anesthesiologists familiar with the potential complications typical of traumatized patients. No particular anesthetic agent or technique is ideal. Causes for intraoperative hypotension include hypovolemia, hemopneumothorax, pericardial tamponade, an intracranial mass, acidosis, and hypothermia. The anesthesiologist should play an active role in all phases of trauma management, including provision of postoperative intensive care and pain relief. 相似文献
16.
C. R. Goucke MB ChB FFARACS J. P. Keaveny MB BCh BAO FFARCS B Kay DMSc MB ChB FFARCS T. E. J. Healy MSc MD FFARCS M. Ryan MB ChB FFARCS 《Anaesthesia》1990,45(4):329-331
Eighty-two outpatients who received general anaesthesia for surgical removal of maxillary or mandibular third molars were given either diclofenac 75 mg or nefopam 20 mg intramuscularly for postoperative pain control. They and the control group were also allowed oral paracetamol as required. The results showed that there was no significant pain relief from these single intramuscular injections. 相似文献
17.
G Etienne M Kassab C Saliou H Kessi J P Becquemin D Melliere 《Journal de chirurgie》1990,127(12):589-591
The potential gravity of post-operative vascular infection makes early diagnosis essential. We report a case where this diagnosis was made on CT findings alone, in the absence of any other signs of infection. Rapid intervention led to complete cure. Beyond the immediate post-operative period, the presence of gas on the CT scan is rare but pathognomonic in the absence of a cutaneous fistula. The presence of this sign is therefore sufficient to indicate that reintervention is mandatory. 相似文献
18.
Robert D Bourke MB BS John Pyle MB BS; FRACO FRACS † 《Clinical & experimental ophthalmology》1994,22(1):77-80
Herpes zoster ophthalmicus (HZO) commonly causes isolated ophthalmoplegic syndromes. Visual loss caused by optic neuritis secondary to HZO can be reversible or irreversible. HZO rarely presents as an orbital apex syndrome, when an association with meningo-encephalitis has been reported. We report a case of orbital apex syndrome secondary to HZO treated with systemic steroids and acyclovir. Our patient suffered no systemic complications and displayed a rapid resolution of optic neuropathy. We discuss this case in the light of previous reports and explore the possible pathogenic mechanisms involved. 相似文献
19.
20.
Suppurative corneal ulceration in Bangladesh 总被引:8,自引:0,他引:8
AAS Dunlop MB BS ED Wright MRCPath † SA Howlader‡ I Nazrul‡ R Husain‡ K McClellan FRACO § FA Billson FRACO § 《Clinical & experimental ophthalmology》1994,22(2):105-110
Suppurative keratitis is an important preventable cause of blindness, particularly in the developing world. This study analyses 142 cases of suppurative keratitis referred to Chittagong Eye Infirmary, Bangladesh. Some 53.5% of cases were bacterial and 35.9% were fungal. The five most common pathogens were: Pseudomonas sp. 24%, Streptococcus pneumoniae 17%, Aspergillus sp. 13%, Fusarium sp. 7% and Curvularia sp. 6%. Gram stain and culture results were consistent in 62.6% of cases. Previous antibiotic treatment was a significant factor for failure of culture isolation and less so for Gram stain failure. On Gram stain, 55.9% of pseudomonal cases were missed, but only 2% of fungal cases were missed. Over all, Gram stain had a sensitivity of 62% and positive predictive value of 84% for bacterial cases, and 98% and 94% for fungal cases, respectively. Fungal ulcers were typically filamentous, but an antecedent history of trauma was not common. The most frequent injury was due to rice grains, but the inoculum appeared to be introduced during eye washing with contaminated water. Pseudomonal ulcers occurred most frequently in the monsoon season, and Fusarium cases were seen only in the hot, dry season. 相似文献