全文获取类型
收费全文 | 2960篇 |
免费 | 197篇 |
国内免费 | 8篇 |
专业分类
耳鼻咽喉 | 25篇 |
儿科学 | 53篇 |
妇产科学 | 60篇 |
基础医学 | 630篇 |
口腔科学 | 41篇 |
临床医学 | 306篇 |
内科学 | 458篇 |
皮肤病学 | 56篇 |
神经病学 | 194篇 |
特种医学 | 69篇 |
外科学 | 607篇 |
综合类 | 18篇 |
一般理论 | 3篇 |
预防医学 | 186篇 |
眼科学 | 66篇 |
药学 | 254篇 |
中国医学 | 7篇 |
肿瘤学 | 132篇 |
出版年
2023年 | 14篇 |
2022年 | 33篇 |
2021年 | 74篇 |
2020年 | 19篇 |
2019年 | 66篇 |
2018年 | 71篇 |
2017年 | 24篇 |
2016年 | 50篇 |
2015年 | 57篇 |
2014年 | 85篇 |
2013年 | 118篇 |
2012年 | 144篇 |
2011年 | 183篇 |
2010年 | 77篇 |
2009年 | 85篇 |
2008年 | 131篇 |
2007年 | 110篇 |
2006年 | 131篇 |
2005年 | 149篇 |
2004年 | 146篇 |
2003年 | 138篇 |
2002年 | 121篇 |
2001年 | 16篇 |
2000年 | 16篇 |
1999年 | 13篇 |
1998年 | 27篇 |
1997年 | 22篇 |
1996年 | 23篇 |
1995年 | 15篇 |
1994年 | 14篇 |
1993年 | 27篇 |
1991年 | 13篇 |
1990年 | 13篇 |
1988年 | 13篇 |
1984年 | 21篇 |
1983年 | 20篇 |
1982年 | 18篇 |
1980年 | 12篇 |
1977年 | 20篇 |
1974年 | 13篇 |
1934年 | 22篇 |
1933年 | 16篇 |
1929年 | 17篇 |
1928年 | 12篇 |
1926年 | 12篇 |
1925年 | 22篇 |
1924年 | 41篇 |
1923年 | 56篇 |
1922年 | 56篇 |
1920年 | 17篇 |
排序方式: 共有3165条查询结果,搜索用时 15 毫秒
71.
Fosbol EL Wang TY Li S Piccini JP Lopes RD Shah B Mills RM Klaskala W Alexander KP Thomas L Roe MT Peterson ED 《American heart journal》2012,163(4):720-728
72.
73.
74.
Mari Auranen Emil Ylikallio Jussi Toppila Mirja Somer Sari Kiuru-Enari Henna Tyynismaa 《Neurogenetics》2013,14(2):123-132
We describe a founder mutation in the gene encoding ganglioside-induced differentiation associated-protein 1 (GDAP1), leading to amino acid change p.H123R, as a common cause of autosomal dominant axonal Charcot-Marie-Tooth (CMT2) neuropathy in Finland. The mutation explains up to 14 % of CMT2 in Finland, where most patients with axonal neuropathy have remained without molecular diagnosis. Only three families out of 28 were found to carry putative disease mutations in the MFN2 gene encoding mitofusin 2. In addition, the MFN2 variant p.V705I was commonly found in our patients, but we provide evidence that this previously described mutation is a common polymorphism and not pathogenic. GDAP1-associated polyneuropathy caused predominantly a mild and slowly progressive phenotype. Besides distal leg muscle weakness, most patients showed mild proximal weakness, often with asymmetry and pes cavus. Our findings broaden the understanding of GDAP1 mutations in CMT2 phenotypes and provide support for the use of whole-exome sequencing in CMT gene diagnostics. 相似文献
75.
76.
Traditional risk factors for cardiovascular disease such as systemic hypertension and hypercholesterolemia, all described more than half a century ago, are relatively few in number. Efforts to expand the epidemiologic canon have met with limited success because of the high hurdle of causality. Fortunately, another solution to current deficiencies in risk assessment-in particular, the underestimation of risk both before and after initiation of pharmacotherapy-may exist. Parallel to the investigation of novel biomarkers, such as high-sensitivity C-reactive protein, ongoing research has yielded improved metrics of known causative conditions. This evolution of traditional risk factors, heralded by measures such as ambulatory blood pressure, central hemodynamics, low density lipoprotein particle concentration, genetic testing, and "vascular age," may better address the detection gap in cardiovascular disease. 相似文献
77.
78.
79.
Charbel G. Salamon Christa Lewis Jennifer Priestley Emil Gurshumov Patrick J. Culligan 《International urogynecology journal》2013,24(8):1371-1375
Introduction and hypothesis
To prospectively evaluate the use of a particular polypropylene Y mesh for robotic sacrocolpopexy.Methods
This was a prospective study of 120 patients who underwent robotic sacrocolpopexy. We compared preoperative and 12-month postoperative objective and subjective assessments via the Pelvic Organ Prolapse Quantification (POP-Q), the Pelvic Floor Distress Inventory, Short Form 20 (PFDI-20); the Pelvic Floor Impact Questionnaire, Short Form 7 (PFIQ-7); and the Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire 12 (PISQ-12). Objective “anatomical success” was defined as POP-Q stage 0 or 1 at all postoperative intervals. We further defined “clinical cure” by simultaneously considering POP-Q points and subjective measures. To be considered a “clinical cure,” a given patient had to have all POP-Q points ≤0, apical POP-Q point C ≤5, no reported pelvic organ prolapse symptoms on the PFDI-20, and no reoperation for prolapse at all postoperative intervals.Results
Of the 120 patients, 118 patients completed the 1-year follow-up. The objective “anatomical success” rate was 89 % and the “clinical cure” rate was 94 %. The PFDI-20 mean score improved from 100.4 at baseline to 21.0 at 12 months (p?<?0.0001); PFIQ-7 scores improved from 61.6 to 8.0 (p?<?0.0001); and PISQ-12 scores improved from 35.7 to 38.6 (p?<?0.0009). No mesh erosions or mesh-related complications occurred.Conclusion
The use of this ultra-lightweight Y mesh for sacrocolpopexy, eliminated the mesh-related complications in the first postoperative year, and provided significant improvement in subjective and objective outcomes. 相似文献80.
Mihai Popescu Valentin Titus Grigorean Crina Julieta Sinescu Cristian Dumitru Lupascu George Popescu Aurelia Mihaela Sandu Iancu Emil Plesea 《Neurologia medico-chirurgica》2013,53(12):890-895
Cavernous haemangioma (cavernoma) is a benign vascular lesion, exceptionally located in cauda equina. We report a case, diagnosed and operated in the Department of Neurosurgery from Pitesti County Emergency Hospital, of a 60-year-old woman with history of lumbar region distress, who presented with low back pain, paravertebral muscle contracture, and bilateral lumbar radiculopathy, with sudden onset after lifting effort. The preoperative diagnosis was done using computed tomography (CT) and magnetic resonance imaging (MRI), and the patient underwent surgery—two level laminectomy, dural incision, and tumor dissection from the cauda equina nerve roots under operatory microscope. Histopathological examination confirmed the positive diagnosis of cavernoma of cauda equina. The patient''s outcome was favorable, without postoperative neurological deficits. 相似文献