全文获取类型
收费全文 | 7467篇 |
免费 | 515篇 |
国内免费 | 57篇 |
专业分类
耳鼻咽喉 | 60篇 |
儿科学 | 152篇 |
妇产科学 | 156篇 |
基础医学 | 943篇 |
口腔科学 | 253篇 |
临床医学 | 525篇 |
内科学 | 1829篇 |
皮肤病学 | 316篇 |
神经病学 | 527篇 |
特种医学 | 449篇 |
外科学 | 1070篇 |
综合类 | 67篇 |
预防医学 | 352篇 |
眼科学 | 240篇 |
药学 | 395篇 |
中国医学 | 20篇 |
肿瘤学 | 685篇 |
出版年
2023年 | 42篇 |
2022年 | 101篇 |
2021年 | 171篇 |
2020年 | 105篇 |
2019年 | 179篇 |
2018年 | 195篇 |
2017年 | 130篇 |
2016年 | 149篇 |
2015年 | 163篇 |
2014年 | 204篇 |
2013年 | 378篇 |
2012年 | 444篇 |
2011年 | 469篇 |
2010年 | 266篇 |
2009年 | 292篇 |
2008年 | 421篇 |
2007年 | 437篇 |
2006年 | 463篇 |
2005年 | 378篇 |
2004年 | 375篇 |
2003年 | 299篇 |
2002年 | 307篇 |
2001年 | 109篇 |
2000年 | 112篇 |
1999年 | 118篇 |
1998年 | 113篇 |
1997年 | 80篇 |
1996年 | 72篇 |
1995年 | 70篇 |
1994年 | 54篇 |
1993年 | 47篇 |
1992年 | 93篇 |
1991年 | 86篇 |
1990年 | 90篇 |
1989年 | 84篇 |
1988年 | 95篇 |
1987年 | 81篇 |
1986年 | 70篇 |
1985年 | 76篇 |
1984年 | 55篇 |
1983年 | 39篇 |
1982年 | 39篇 |
1981年 | 38篇 |
1980年 | 39篇 |
1979年 | 42篇 |
1978年 | 33篇 |
1977年 | 29篇 |
1976年 | 38篇 |
1975年 | 30篇 |
1974年 | 31篇 |
排序方式: 共有8039条查询结果,搜索用时 0 毫秒
151.
Vanessa Vorhies Klodnick Kristin E. Davis Marc A. Fagan Allison Elias 《Community mental health journal》2014,50(2):209-215
This qualitative study explores the experiences of emerging adults with serious mental health conditions (e.g., bipolar disorder, posttraumatic stress disorder) before and after they emancipate from the child welfare system and exit a transitional living program. Sixteen participants were interviewed before and 13 were interviewed after aging out. Findings suggest that transitional living programs services were appreciated for the relationships and safety net they fostered. Future plans were positive, but vague, and worries about the future were prevalent. Struggles with independence post-emancipation were common despite adult service use. Additional research is needed to understand how to best support these at-risk emerging adults. 相似文献
152.
153.
O'Hara GA Duncan CJ Ewer KJ Collins KA Elias SC Halstead FD Goodman AL Edwards NJ Reyes-Sandoval A Bird P Rowland R Sheehy SH Poulton ID Hutchings C Todryk S Andrews L Folgori A Berrie E Moyle S Nicosia A Colloca S Cortese R Siani L Lawrie AM Gilbert SC Hill AV 《The Journal of infectious diseases》2012,205(5):772-781
154.
155.
156.
Tai YT Chang BY Kong SY Fulciniti M Yang G Calle Y Hu Y Lin J Zhao JJ Cagnetta A Cea M Sellitto MA Zhong MY Wang Q Acharya C Carrasco DR Buggy JJ Elias L Treon SP Matsui W Richardson P Munshi NC Anderson KC 《Blood》2012,120(9):1877-1887
Bruton tyrosine kinase (Btk) has a well-defined role in B-cell development, whereas its expression in osteoclasts (OCs) further suggests a role in osteoclastogenesis. Here we investigated effects of PCI-32765, an oral and selective Btk inhibitor, on osteoclastogenesis as well as on multiple myeloma (MM) growth within the BM microenvironment. PCI-32765 blocked RANKL/M-CSF-induced phosphorylation of Btk and downstream PLC-γ2 in OCs, resulting in diminished TRAP5b (ED(50) = 17nM) and bone resorption activity. PCI-32765 also inhibited secretion of multiple cytokines and chemokines from OC and BM stromal cell cultures from both normal donors (ED(50) = 0.5nM) and MM patients. It decreased SDF-1-induced migration of MM cells, and down-regulated MIP1-α/CCL3 in MM cells. It also blocked MM cell growth and survival triggered by IL-6 or coculture with BM stromal cells or OCs in vitro. Importantly, PCI-32765 treatment significantly inhibits in vivo MM cell growth (P < .03) and MM cell-induced osteolysis of implanted human bone chips in SCID mice. Moreover, PCI-32765 prevents in vitro colony formation by stem-like cells from MM patients. Together, these results delineate functional sequelae of Btk activation mediating osteolysis and growth of MM cells, supporting evaluation of PCI-32765 as a novel therapeutic in MM. 相似文献
157.
158.
People tend to display the left cheek when posing for a portrait; however, this effect does not appear to generalise to advertising. The amount of body visible in the image and the sex of the poser might also contribute to the posing bias. Portraits also exhibit lateral lighting biases, with most images being lit from the left. This effect might also be present in advertisements. A total of 2801 full-page advertisements were sampled and coded for posing direction, lighting direction, sex of model, and amount of body showing. Images of females showed an overall leftward posing bias, but the biases in males depended on the amount of body visible. Males demonstrated rightward posing biases for head-only images. Overall, images tended to be lit from the top left corner. The two factors of posing and lighting biases appear to influence one another. Leftward-lit images had more leftward poses than rightward, while the opposite occurred for rightward-lit images. Collectively, these results demonstrate that the posing biases in advertisements are dependent on the amount of body showing in the image, and that biases in lighting direction interact with these posing biases. 相似文献
159.
160.