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排序方式: 共有866条查询结果,搜索用时 15 毫秒
861.
Zayd A. Eldadah MD PhD Amin Al-Ahmad MD T. Jared Bunch MD David B. Delurgio MD Rahul N. Doshi MD Bruce G. Hook MD Patrick M. Hranitzky MD Charles A. Joyner MD Suneet Mittal MD Christopher Porterfield MD Javier E. Sanchez MD Senthil K. Thambidorai MD Oussama M. Wazni MD H. Thomas McElderry MD 《Journal of cardiovascular electrophysiology》2023,34(2):348-355
862.
863.
Doshi Ankur M. Ostrow Dana Gresens August Grimmelmann Rachel Mazhar Salman Neto Eduardo Woodriff Molly Recht Michael 《Journal of digital imaging》2023,36(4):1285-1290
Journal of Digital Imaging - Many outpatient radiology orders are never scheduled, which can result in adverse outcomes. Digital appointment self-scheduling provides convenience, but utilization... 相似文献
864.
Beatrice P. Concepcion Meera Harhay Jay Ruterbories Jan Finn Alex Wiseman Matthew Cooper Sumit Mohan Mona D. Doshi 《Clinical transplantation》2023,37(4):e14925
Organ procurement organizations (OPOs) play a central role in the recovery, preservation, and distribution of deceased donor kidneys for transplantation in the United States. We conducted a national survey to gather information on OPO practices and perceived barriers to efficient organ placement in the face of the new circle-based allocation and asked for suggestions to overcome them. Of the 57 OPOs, 44 responded (77%). The majority of OPOs (61%) reported barriers to obtaining a kidney biopsy, including lack of an available pathologist. Most OPOs (55%) indicated barriers to pumping owing to a lack of available staff and transportation. Respondents agreed or strongly agreed that the new allocation system has worsened transportation challenges (85%), increased provisional acceptances of kidneys (66%), increased communication challenges with transplant centers (68%), and worsened the efficiency of organ allocation (83%). OPO-suggested solutions include making transplant centers more accountable for inefficient selection practices, developing reliable transportation options, and removing the requirement for national sharing. These findings underscore the need to examine closely the trade-offs of the new allocation system with respect to costs, organ ischemia, and discard. These findings may help inform practice and policy for overcoming transportation barriers and improving the efficiency of organ placement. 相似文献
865.
Thomas Williams Nevin John Alberto Calvi Alessia Bianchi Floriana De Angelis Anisha Doshi Sarah Wright Madiha Shatila Marios C. Yiannakas Fatima Chowdhury Jon Stutters Antonio Ricciardi Ferran Prados David MacManus Marie Braisher James Blackstone Olga Ciccarelli Claudia A. M. Gandini Wheeler-Kingshott Frederik Barkhof Jeremy Chataway the UCL MS-STAT investigators 《European journal of neurology》2023,30(9):2769-2780
Background and purpose
There is increasing evidence that cardiovascular risk (CVR) contributes to disability progression in multiple sclerosis (MS). CVR is particularly prevalent in secondary progressive MS (SPMS) and can be quantified through validated composite CVR scores. The aim was to examine the cross-sectional relationships between excess modifiable CVR, whole and regional brain atrophy on magnetic resonance imaging, and disability in patients with SPMS.Methods
Participants had SPMS, and data were collected at enrolment into the MS-STAT2 trial. Composite CVR scores were calculated using the QRISK3 software. Prematurely achieved CVR due to modifiable risk factors was expressed as QRISK3 premature CVR, derived through reference to the normative QRISK3 dataset and expressed in years. Associations were determined with multiple linear regressions.Results
For the 218 participants, mean age was 54 years and median Expanded Disability Status Scale was 6.0. Each additional year of prematurely achieved CVR was associated with a 2.7 mL (beta coefficient; 95% confidence interval 0.8–4.7; p = 0.006) smaller normalized whole brain volume. The strongest relationship was seen for the cortical grey matter (beta coefficient 1.6 mL per year; 95% confidence interval 0.5–2.7; p = 0.003), and associations were also found with poorer verbal working memory performance. Body mass index demonstrated the strongest relationships with normalized brain volumes, whilst serum lipid ratios demonstrated strong relationships with verbal and visuospatial working memory performance.Conclusions
Prematurely achieved CVR is associated with lower normalized brain volumes in SPMS. Future longitudinal analyses of this clinical trial dataset will be important to determine whether CVR predicts future disease worsening. 相似文献866.
Machine learning approach for obstructive sleep apnea screening using brain diffusion tensor imaging
Bo Pang Suraj Doshi Bhaswati Roy Milena Lai Luke Ehlert Ravi S. Aysola Daniel W. Kang Ariana Anderson Shantanu H. Joshi Daniel Tward Fabien Scalzo Susana Vacas Rajesh Kumar 《Journal of sleep research》2023,32(1):e13729
Patients with obstructive sleep apnea (OSA) show autonomic, mood, cognitive, and breathing dysfunctions that are linked to increased morbidity and mortality, which can be improved with early screening and intervention. The gold standard and other available methods for OSA diagnosis are complex, require whole-night data, and have significant wait periods that potentially delay intervention. Our aim was to examine whether using faster and less complicated machine learning models, including support vector machine (SVM) and random forest (RF), with brain diffusion tensor imaging (DTI) data can classify OSA from healthy controls. We collected two DTI series from 59 patients with OSA [age: 50.2 ± 9.9 years; body mass index (BMI): 31.5 ± 5.6 kg/m2; apnea-hypopnea index (AHI): 34.1 ± 21.2 events/h 23 female] and 96 controls (age: 51.8 ± 9.7 years; BMI: 26.2 ± 4.1 kg/m2; 51 female) using a 3.0-T magnetic resonance imaging scanner. Using DTI data, mean diffusivity maps were calculated from each series, realigned and averaged, normalised to a common space, and used to conduct cross-validation for model training and selection and to predict OSA. The RF model showed 0.73 OSA and controls classification accuracy and 0.85 area under the curve (AUC) value on the receiver-operator curve. Cross-validation showed the RF model with comparable fitting over SVM for OSA and control data (SVM; accuracy, 0.77; AUC, 0.84). The RF ML model performs similar to SVM, indicating the comparable statistical fitness to DTI data. The findings indicate that RF model has similar AUC and accuracy over SVM, and either model can be used as a faster OSA screening tool for subjects having brain DTI data. 相似文献