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García-Pardo AR Pérez Díaz D Machado Liendo PJ Cortese S Atahualpa Arenas F Turégano Fuentes F 《Acta gastroenterologica Latinoamericana》2012,42(1):46-49
Esophageal ingestion of foreign bodies is a frequent urgency. It occurs more commonly in patients with psychiatric disorders, prisoners and extreme ages of the life. Early upper endoscopy is the method of choice for the treatment of symptomatic patients. Surgery is only considered when a complication is present or the extraction can not be done by the endoscopist. We report a case of a 34-year-old male who voluntarily ingested an uncommon foreign body. Surgical treatment was required because of impaction after endoscopic maneuvers and suspicion of esophageal perforation. 相似文献
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DeLario MR Sheehan AM Ataya R Bertuch AA Vega C Webb CR Lopez-Terrada D Venkateswaran L 《American journal of hematology》2012,87(5):461-464
Primary myelofibrosis is a chronic myeloproliferative neoplasm characterized by cytopenias, leukoerythroblastosis, extramedullary hematopoiesis, hepatosplenomegaly and bone marrow fibrosis. Primary myelofibrosis is a rare disorder in adults; children are even less commonly affected by this entity, with the largest pediatric case series reporting on three patients. Most literature suggests spontaneous resolution of myelofibrosis without long term complications in the majority of affected children. We describe the clinical, pathologic, and molecular characteristics and outcomes of nineteen children with primary myelofibrosis treated in our center from 1984 to 2011. Most patients had cytopenia significant enough to require supportive therapy. No child developed malignant transformation and only five of the 19 children (26%) had spontaneous resolution of disease. Sequence analyses for JAK2V617F and MPLW515L mutations were performed on bone marrow samples from 17 and six patients, respectively, and the results were negative. In conclusion, analysis of this large series of pediatric patients with primary myelofibrosis demonstrates distinct clinical, hematologic, bone marrow, and molecular features from adult patients. 相似文献
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García-Fuertes D Mesa-Rubio D Ruiz-Ortiz M Delgado-Ortega M Tejero-Mateo I Pan-Álvarez-Ossorio M Suárez-de-Lezo J Lafuente M 《Echocardiography (Mount Kisco, N.Y.)》2012,29(6):729-734
Background: Atrial septal defect (ASD) is one of the most common congenital heart diseases. Nowadays, percutaneous closure is considered the treatment of choice in most of secundum ASDs. Assessment of the defect and procedure monitoring have been usually performed by angiographic balloon‐sizing and/or two‐dimensional (2D) transesophageal echocardiography. However, in complex ASDs these techniques might be inaccurate. Methods: From January 2009 to January 2011 all adult patients with complex ASDs submitted for percutaneous closure were selected. Those defects, where shunts were present through a device previously implanted on the atrial septum or through multiperforated septums, were considered complex ASDs. Two‐dimensional transesophageal echocardiography and real time three‐dimensional (3D) echocardiography were performed simultaneously during the percutaneous closure procedure. Number of orifices, relationships between the defect, catheter, and device, as well as residual shunt were assessed. Results: Seven patients were included. Five patients had a multiperforated septum and in two cases the defect in the septum was through a previously implanted device. In all cases, 3D echocardiography was superior to 2D echocardiography in relation to the assessment of the relationship between the defect and the catheter or the device. Mechanisms responsible for residual shunts through a device were also better assessed by 3D echocardiography. Conclusion: Three‐dimensional echocardiography is a safe and useful technique when monitoring percutaneous closure of ASDs, showing relevant advantages over 2D echocardiography. (Echocardiography 2012;29:729‐734) 相似文献
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