全文获取类型
收费全文 | 220篇 |
免费 | 12篇 |
国内免费 | 2篇 |
专业分类
儿科学 | 10篇 |
妇产科学 | 6篇 |
基础医学 | 16篇 |
口腔科学 | 1篇 |
临床医学 | 9篇 |
内科学 | 54篇 |
皮肤病学 | 11篇 |
神经病学 | 4篇 |
特种医学 | 58篇 |
外科学 | 9篇 |
综合类 | 14篇 |
预防医学 | 9篇 |
眼科学 | 3篇 |
药学 | 16篇 |
肿瘤学 | 14篇 |
出版年
2023年 | 1篇 |
2022年 | 5篇 |
2021年 | 1篇 |
2020年 | 2篇 |
2019年 | 1篇 |
2018年 | 1篇 |
2017年 | 3篇 |
2016年 | 2篇 |
2015年 | 3篇 |
2014年 | 6篇 |
2013年 | 7篇 |
2012年 | 5篇 |
2011年 | 6篇 |
2010年 | 6篇 |
2009年 | 13篇 |
2008年 | 9篇 |
2007年 | 9篇 |
2006年 | 6篇 |
2005年 | 9篇 |
2004年 | 3篇 |
2003年 | 4篇 |
2001年 | 5篇 |
2000年 | 1篇 |
1999年 | 4篇 |
1998年 | 7篇 |
1997年 | 12篇 |
1996年 | 10篇 |
1995年 | 12篇 |
1994年 | 8篇 |
1993年 | 14篇 |
1992年 | 3篇 |
1991年 | 2篇 |
1990年 | 3篇 |
1989年 | 7篇 |
1988年 | 10篇 |
1987年 | 10篇 |
1986年 | 6篇 |
1985年 | 3篇 |
1983年 | 1篇 |
1982年 | 2篇 |
1981年 | 3篇 |
1980年 | 1篇 |
1979年 | 1篇 |
1978年 | 2篇 |
1977年 | 3篇 |
1976年 | 1篇 |
1970年 | 1篇 |
排序方式: 共有234条查询结果,搜索用时 15 毫秒
41.
42.
Jha T Seth S Bhattacharyya D Bhattacharyay AR Sengupta M Das A Dhali B 《Journal of the Indian Medical Association》2011,109(10):703-707
The question regarding the optimal age of delivery in twins remains unanswered. A prospective observational study was carried out in the gynaecology and obstetrics department of RG Kar Medical College and Hospital, Kolkata during 2008-2009 to arrive at a logical conclusion to this question. The objective of this study was to evaluate the optimal timing of delivery in twins and compare the perinatal outcome in these babies by dividing them into 3 groups: 34 weeks to 35 weeks 6 days, 36 weeks to 37 weeks 6 days and >38 weeks. Perinatal outcome was also compared between different modes of delivery. Few maternal complications like pre-eclampsia, anaemia, premature rupture of membrane, preterm labour and antepartum haemorrhage were also evaluated. 相似文献
43.
Farheen S Sengupta S Santra A Pal S Dhali GK Chakravorty M Majumder PP Chowdhury A 《World journal of gastroenterology : WJG》2006,12(14):2269-2275
44.
Mitochondrial oxidative stress and permeability transition in isoniazid and rifampicin induced liver injury in mice 总被引:3,自引:0,他引:3
Chowdhury A Santra A Bhattacharjee K Ghatak S Saha DR Dhali GK 《Journal of hepatology》2006,45(1):117-126
BACKGROUND/AIMS: To evaluate the role of mitochondrial oxidative stress and permeability transition (MPT) in isoniazid (INH) and rifampicin (RMP) induced hepatotoxicity in mice. METHODS: Liver damage was induced by co-treatment of INH (50 mg/kg) and RMP (100 mg/kg). Pre-treatment with either methionine or phorone was done to modulate hepatic GSH level. Liver cell injury was assessed biochemically and histologically.Evidence of apoptosis was sought by TUNEL test, caspase assay and histology. RESULTS: INH and RMP co-treatment caused steatosis and increased apoptosis of the hepatocytes, hepatic oxidative stress, particularly in the mitochondrial fraction with increased mitochondrial permeability transition (MPT).Mitochondrial oxidative stress as well as liver cell injury was increased by prior treatment with phorone. This was attenuated by pretreatment with methionine suggesting a glutathione (GSH) dependent phenomenon. CONCLUSIONS: Oxidative stress in the mitochondria and inappropriate MPT are important in the pathogenesis of apoptotic liver cell injury in INH-RMP hepatotoxicity. The phenomenon is GSH dependent and methionine supplementation might have a protective role. 相似文献
45.
Rajni Gupta Jugal Kishore Yogesh Bansal MK Daga RC Jiloha Rajeev Singal GK Ingle 《Indian Journal of Community Medicine》2011,36(3):182-186
Objective:
To investigate the relationship of psychosocial factors (lack of social support, stress and subjective well-being) and personality traits with myocardial infarction (MI).Materials and Methods:
A case–control study involving 100 cases and 100 matched controls was conducted in Lok Nayak Hospital, New Delhi.Results:
Stress over 1 year was significantly higher in cases (P < 0.001). However, difference was not significant when scores of social support (P = 0.2), Presumptive Stressful Life Event (PSLE) over lifetime (P = 0.058) and subjective well-being (P = 0.987) were compared. MI was significantly associated with hyperactive (P < 0.001), dominant (P = 0.03), egoistic (P < 0.001) and introvert (P < 0.001) personalities.Conclusion:
Certain personality traits and recent stress may be important risk factors of MI, especially in Indians. The finding may have implications on the preventive strategies planned for MI patients. 相似文献46.
47.
A Chowdhury A Santra S Kundu A Mukherjee A Pandit S Chaudhuri G K Dhali 《Indian journal of gastroenterology》2001,20(3):97-100
BACKGROUND AND AIM: Oxidative stress could play a role in the pathogenesis of antitubercular drug (ATD)-induced hepatotoxicity. We therefore studied the plasma level of reduced glutathione (GSH) and malondialdehyde (MDA) in patients with ATD-induced hepatotoxicity (cases), ATD-treated controls (disease controls) and in healthy volunteers. METHODS: This study was carried out in a case-control design. Twenty-one cases, 21 age- and sex-matched disease controls, and 10 healthy volunteers were enrolled. Plasma levels of GSH and MDA were measured. RESULTS: Plasma levels of GSH (median [range] 11.5 [6.2-21.2] mmol/dL) and MDA (1390 [560-2310] nmol/dL) of cases were significantly different (p<0.01) from GSH (18.4 [10.5-24.4]) and MDA (290 [240-550]) of disease controls. Further, plasma GSH and MDA levels of both the ATD-treated groups were different from those in healthy controls. CONCLUSION: Lower levels of plasma GSH and higher levels of MDA may be due to oxidative stress resulting from ATD therapy. 相似文献
48.
Pui CH; Ip SH; Iflah S; Behm FG; Grose BH; Dodge RK; Crist WM; Furman WL; Murphy SB; Rivera GK 《Blood》1988,71(4):1135-1137
The clinical significance of interleukin 2 receptor (IL2R) concentrations in serum was determined for 344 children with newly diagnosed acute lymphoblastic leukemia (ALL). Serum levels of IL2R in patients (267 to 80,000 U/mL, median 2,007 U/mL) were significantly higher than normal control values (170 to 738 U/mL, median 347 U/mL) (P less than .0001). Measurements in cases of T cell ALL were lower than in the non-T, non-B cases (P = .02). Among the 264 patients with non-T, non-B ALL, but not in those with T cell disease, higher serum IL2R levels (greater than 2,000 U/mL) were associated with a poorer treatment outcome (P = .04). In a multivariate analysis, serum IL2R level contributed independent prognostic information beyond that conveyed by leukocyte count, race, and age (P = .04). One explanation for these results is that soluble IL2R competes with normal lymphocyte- integrated IL2R for the ligand and thus could suppress host antitumor immunity. 相似文献
49.
50.