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排序方式: 共有264条查询结果,搜索用时 15 毫秒
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Gialousis GI Yakoumakis EN Dimitriadis AI Papouli ZK Yakoumakis NE Tsalafoutas IA Papadopoulou DI Georgiou EK 《Health physics》2008,95(3):331-336
Radiation exposure was investigated for children undergoing various common radiographies in three dedicated pediatric hospitals in Greece. Kerma in air at the entrance of the beam (Ka,e) was measured with thermoluminescent dosimeters. Ka,e values ranged from 0.09 mGy to 5.52 mGy and were found to be greater in Hospital C, because of the increased high voltage and time-current product used by the radiation technologists. Equivalent doses in red bone marrow and breast were estimated with Monte Carlo simulation by PCXMC code. Values ranged from 2 microSv to 204 microSv for red bone marrow and from 0 to 817 muSv for breast. Variation in doses occurred due to field size, high voltage setting, and Ka,e. 相似文献
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Xanthopoulou D Bakker AB Heuven E Demerouti E Schaufeli WB 《Journal of occupational health psychology》2008,13(4):345-356
This study aims to gain insight in the motivational process of the Job Demands-Resources (JD-R) model by examining whether daily fluctuations in colleague support (i.e., a typical job resource) predict day-levels of job performance through self-efficacy and work engagement. Forty-four flight attendants filled in a questionnaire and a diary booklet before and after consecutive flights to three intercontinental destinations. Results of multilevel analyses revealed that colleague support had unique positive effects on self-efficacy and work engagement. Self-efficacy did not mediate the relationship between support and engagement, but work engagement mediated the relationship between self-efficacy and (in-role and extra-role) performance. In addition, colleague support had an indirect effect on in-role performance through work engagement. These findings shed light on the motivational process as outlined in the JD-R model, and suggest that colleague support is an important job resource for flight attendants helping them reach their work-related goals. 相似文献
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Amalia Baroutidou;Despoina Ntiloudi;Nearchos Kasinos;Evangelia Nyktari;George Giannakoulas; 《Echocardiography (Mount Kisco, N.Y.)》2024,41(1):e15749
A comprehensive and structured imaging approach in the evaluation of the systemic right ventricle (sRV) in patients with complete transposition of the great arteries (TGA) after atrial switch procedure and congenitally corrected transposition of the great arteries (ccTGA) is a key for their optimal lifelong surveillance. Despite the improvements in cardiovascular imaging of adults with congenital heart disease (ACHD), the imaging of sRV remains an ongoing challenge due to its complex morphology and the difficulty in applying the existing knowledge for the systemic left ventricle. While cardiac magnetic resonance (CMR) is considered the gold standard imaging method, echocardiographic evaluation is primarily preferred in everyday clinical setting. Although qualitative assessment of its systolic function is primarily used, the introduction of advanced echocardiographic techniques, such as speckle tracking echocardiography (STE) and three-dimensional echocardiography (3DE), has provided new insights into the optimal assessment of the sRV. Standardized quantitative parameters remain to be elucidated, and morphometric and mechanistic studies are warranted to validate reference ranges for the sRV. This review highlights the challenges in the optimal evaluation of sRV and summarizes the available imaging tools. 相似文献
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Ioannis Temponeras Martina Samiotaki Despoina Koumantou Martha Nikopaschou Jonas J.W. Kuiper George Panayotou Efstratios Stratikos 《European journal of immunology》2023,53(8):2350449
ER aminopeptidase 1 (ERAP1) is an ER-resident aminopeptidase that excises N-terminal residues of peptides that then bind onto Major Histocompatibility Complex I molecules (MHC-I) and indirectly modulates adaptive immune responses. ERAP1 contains an allosteric regulatory site that accommodates the C-terminus of at least some peptide substrates, raising questions about its exact influence on antigen presentation and the potential of allosteric inhibition for cancer immunotherapy. We used an inhibitor that targets this regulatory site to study its effect on the immunopeptidome of a human cancer cell line. The immunopeptidomes of allosterically inhibited and ERAP1 KO cells contain high-affinity peptides with sequence motifs consistent with the cellular HLA class I haplotypes but are strikingly different in peptide composition. Compared to KO cells, allosteric inhibition did not affect the length distribution of peptides and skewed the peptide repertoire both in terms of sequence motifs and HLA allele utilization, indicating significant mechanistic differences between the two ways of disrupting ERAP1 function. These findings suggest that the regulatory site of ERAP1 plays distinct roles in antigenic peptide selection, which should be taken into consideration when designing therapeutic interventions targeting the cancer immunopeptidome. 相似文献
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Eftychia Ferentinou ;Ioannis Koutelekos ;Evangelos Dousis ;Eleni Evangelou ;Despoina Pappa ;Maria Theodoratou ;Chrysoula Dafogianni 《AIMS Public Health》2025,12(1):77-90
Sleep duration and quality have been increasingly recognized as critical determinants of childhood obesity risk, with insufficient sleep linked to disruptions in appetite-regulating hormones and unhealthy weight gain trajectories. Emotional intelligence, which involves recognizing, understanding, and managing one's own emotions as well as those of others, has garnered attention for its potential impact on VARIOUS aspects of health and well-being, including weight management. Moreover, childhood obesity remains a significant public health concern worldwide, with multifaceted factors contributing to its prevalence and persistence. Research is starting to reveal how sleep patterns and emotional intelligence (ΕΙ) influence children's weight status. This study aims to investigate the relationship between childhood sleep patterns, EI, and body mass index (BMI) in school-aged children. Utilizing a sample of 614 children, aged 8–12 years (mean age 10.0 y), data on emotional intelligence scores, sleep duration and quality, and BMI measurements were collected and analyzed. The results reveal significant correlations among these variables, indicating that emotional intelligence may play a crucial role in both sleep patterns and BMI outcomes in children (Mean = 3.53, SD = 0.51 in total sample; Mean = 3.53, SD = 0.51 in overweight/obese). Specifically, higher emotional intelligence scores are associated with better sleep quality and duration, as well as healthier BMI levels (p ≤ 0.001). These findings underscore the importance of considering emotional well-being and sleep hygiene in the context of childhood obesity prevention and intervention efforts. Further research is needed to elucidate the underlying mechanisms driving these relationships and to develop targeted strategies for promoting emotional intelligence and healthy sleep habits in school-aged children. 相似文献
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Maria Gavriatopoulou Evangelos Terpos Ioannis Ntanasis-Stathopoulos Ioannis Papasotiriou Despoina Fotiou Magdalini Migkou Maria Roussou Nikolaos Kanellias Dimitrios Ziogas Ioanna Dialoupi Evangelos Eleutherakis Papaiakovou Efstathios Kastritis Meletios Athanasios Dimopoulos 《Clinical Lymphoma, Myeloma & Leukemia》2019,19(1):23-28