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121.
122.
Severe adverse effects during the use of ovulation inhibitors occur mostly in women who have an elevated risk for the development of certain diseases owing to hereditary or acquired factors. By means of a careful personal or family history analysis as well as specific laboratory examinations, an existing predisposition may frequently be diagnosed and the individual risk associated with the use of oral contraceptive inhibitors may be estimated. The present contribution describes the potential effects of treatment with ovulation inhibitors on women with thrombophilia, cardiovascular disease, diabetes mellitus, dyslipidemia, overweight or underweight, tumors, psychiatric and neurological diseases and autoimmune disease. The hormonal methods and non-hormonal alternatives available for contraception are elucidated according to existing lesions and risk factors and the advantages and disadvantages are discussed. 相似文献
123.
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125.
Abstract Chorea is a rare complication of polycythaemia vera. Polycythaemic chorea occurs predominantly in females and usually in generalised
form. We present a 66-year-old woman with acute onset hemichorea-ballism with no vascular pathology in the basal ganglia region.
A clear relationship was observed between the onset of chorea and worsening of haematological parameters in the patient. After
repeated phlebotomies the patient's clinical status was improved. Polycythaemic chorea must be considered, especially in the
elderly, as early diagnosis leads to effective treatment and prevention of complications. 相似文献
126.
J I?igo A Arce E Rodríguez D García de Viedma E Palenque M J Ruiz Serrano L Cabello F Chaves 《The international journal of tuberculosis and lung disease》2006,10(5):550-553
SETTING: Tuberculosis (TB) cases reported from nine districts of Madrid, where the percentage of immigrant population varied from 1.9% in 1996 to 12.2% in 2003. OBJECTIVE: To describe the trends in TB incidence from 1994 to 2003. DESIGN: Observational study. RESULTS: Between 1994-1995 and 2002-2003, the TB rate decreased from 48.5 (95% CI 45.8-51.1) to 23.3 per 100000 population (95% CI 21.5-25.1) (P < 0.001). The percentage of TB cases co-infected with HIV decreased from 55.9% in 1994 to 14.3% in 2003 (P < 0.001), whereas TB cases in foreigners increased from 2.6% in 1994 to 33.7% in 2003 (P < 0.001). CONCLUSION: Although the TB rates showed a marked decrease in the study period, the increasing impact of immigration contributed to slowing down the trend. 相似文献
127.
Hale Sayan V Haktan Ozacmak Aysel Guven R Gulhan Aktas I Diler Ozacmak 《Journal of investigative surgery》2006,19(3):163-173
Erythropoietin exerts hematopoietic effects by stimulating proliferation of early erythroid precursors. Nonhematopoietic effects of erythropoietin have also been shown. It may act as a new angiogenic factor in wound healing. This study aimed to investigate the effect of systemic administration of recombinant human erythropoietin on wound healing in mice. Dorsal incisional wounds were performed in mice, which were then divided into two groups; a group treated for 7 days with recombinant human erythropoietin, and a control group. Sacrificing animals on day 7, the wound tissues were collected for analysis of wound breaking strength, malondialdehyde, a marker of lipid peroxidation, hydroxyproline, an index of reparative collagen deposition, reduced glutathione levels, and for histological evaluation. The immunohistochemical determination of vascular endothelial growth factor (VEGF) which is believed to be the most prevalent angiogenic factor throughout the skin repair process, was also studied. The treatment significantly increased wound breaking strength by decreasing malondialdehyde and increasing hydroxyproline levels on day 7 after wounding. No statistically meaningful change was observed in reduced glutathione content. VEGF was immunostained significantly more on wound tissue of treated animals compared to the control group. Recombinant human erythropoietin treatment may be effective in wound healing due to inhibition of lipid peroxidation, deposition of collagen, and VEGF expression in wound area. 相似文献
128.
N. N. Polygalova A. G. Mikhailovskii E. S. Limanskii B. Ya. Syropyatov M. I. Vakhrin 《Pharmaceutical Chemistry Journal》2006,40(3):132-134
A series of 1-alkyl-3,4-dihydroisoquinolines and the related 4-alkyl-1,2-dihydro-benzo[f]isoquinolines was synthesized using
reactions of dialkylbenzylcarbinols and their naphthyl analogs with alkylcyanides. Experiments showed that 1-alkyl-6,7-dimethoxy-3,4-dihydroisoquinolines
typically produce a hypotensive action, while the benzo-annelated structures usually exhibit a hypertensive effects. The most
active compound decreases the arterial pressure in cats by 52 Torr and the effect lasts for about 4 hours.
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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 40, No. 3, pp. 15–17, March, 2006. 相似文献
129.
I. V. Shilova E. A. Krasnov E. I. Korotkova M. G. Nagaev A. N. Lukina 《Pharmaceutical Chemistry Journal》2006,40(12):660-662
Extracts of the above-ground part of meadowsweet (Filipendula ulmaria L. Maxim.) demonstrate a pronounced antioxidant activity. It is established that 70% and 95% ethanol extracts contain the
most active substances. Investigation of the chemical composition of the above-ground part of the plant and its 70% ethanol
extract by means of qualitative reactions, thin-layer chromatography, and paper chromatography showed the presence of various
phenolic compounds, including quercetin and its glycosides, dihydroquercetin, apigenin, rododendrol, esculetin, and m-hydroxybenzoic, salicylic, anisic, gallic, gentisic, ferulic, chlorogenic, and caffeic acids.
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Translated From Khimiko-Farmatsevticheskii Zhurnal, Vol. 40, No. 12, Pp. 22–24, December, 2006. 相似文献
130.