全文获取类型
收费全文 | 2222058篇 |
免费 | 166929篇 |
国内免费 | 7369篇 |
专业分类
耳鼻咽喉 | 29690篇 |
儿科学 | 71201篇 |
妇产科学 | 59995篇 |
基础医学 | 308509篇 |
口腔科学 | 62026篇 |
临床医学 | 199557篇 |
内科学 | 441072篇 |
皮肤病学 | 52152篇 |
神经病学 | 177146篇 |
特种医学 | 90393篇 |
外国民族医学 | 472篇 |
外科学 | 343469篇 |
综合类 | 49386篇 |
现状与发展 | 3篇 |
一般理论 | 656篇 |
预防医学 | 168849篇 |
眼科学 | 48825篇 |
药学 | 165084篇 |
10篇 | |
中国医学 | 4553篇 |
肿瘤学 | 123308篇 |
出版年
2018年 | 22462篇 |
2017年 | 17767篇 |
2016年 | 20937篇 |
2015年 | 23316篇 |
2014年 | 32229篇 |
2013年 | 47892篇 |
2012年 | 61178篇 |
2011年 | 65342篇 |
2010年 | 39932篇 |
2009年 | 38474篇 |
2008年 | 61009篇 |
2007年 | 65142篇 |
2006年 | 66596篇 |
2005年 | 63902篇 |
2004年 | 61165篇 |
2003年 | 59351篇 |
2002年 | 56874篇 |
2001年 | 112346篇 |
2000年 | 115721篇 |
1999年 | 96606篇 |
1998年 | 26860篇 |
1997年 | 23891篇 |
1996年 | 24661篇 |
1995年 | 24264篇 |
1994年 | 22433篇 |
1993年 | 21130篇 |
1992年 | 77180篇 |
1991年 | 74835篇 |
1990年 | 72643篇 |
1989年 | 69729篇 |
1988年 | 63912篇 |
1987年 | 62616篇 |
1986年 | 59043篇 |
1985年 | 56423篇 |
1984年 | 42066篇 |
1983年 | 35396篇 |
1982年 | 21067篇 |
1981年 | 18654篇 |
1980年 | 17653篇 |
1979年 | 37823篇 |
1978年 | 26601篇 |
1977年 | 23009篇 |
1976年 | 20666篇 |
1975年 | 22313篇 |
1974年 | 26106篇 |
1973年 | 25096篇 |
1972年 | 23493篇 |
1971年 | 21837篇 |
1970年 | 20001篇 |
1969年 | 18993篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
991.
992.
993.
994.
Rodica Pop-Busui Jiang Lu Neuza Lopes Teresa L. Z. Jones and the BARI D Investigators 《Journal of the peripheral nervous system : JPNS》2009,14(1):1-13
Abstract We evaluated the associations between glycemic therapies and prevalence of diabetic peripheral neuropathy (DPN) at baseline among participants in the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) trial on medical and revascularization therapies for coronary artery disease (CAD) and on insulin-sensitizing vs. insulin-providing treatments for diabetes. A total of 2,368 patients with type 2 diabetes and CAD was evaluated. DPN was defined as clinical examination score >2 using the Michigan Neuropathy Screening Instrument (MNSI). DPN odds ratios across different groups of glycemic therapy were evaluated by multiple logistic regression adjusted for multiple covariates including age, sex, hemoglobin A1c (HbA1c), and diabetes duration. Fifty-one percent of BARI 2D subjects with valid baseline characteristics and MNSI scores had DPN. After adjusting for all variables, use of insulin was significantly associated with DPN (OR = 1.57, 95% CI: 1.15–2.13). Patients on sulfonylurea (SU) or combination of SU/metformin (Met)/thiazolidinediones (TZD) had marginally higher rates of DPN than the Met/TZD group. This cross-sectional study in a cohort of patients with type 2 diabetes and CAD showed association of insulin use with higher DPN prevalence, independent of disease duration, glycemic control, and other characteristics. The causality between a glycemic control strategy and DPN cannot be evaluated in this cross-sectional study, but continued assessment of DPN and randomized therapies in BARI 2D trial may provide further explanations on the development of DPN. 相似文献
995.
K. A. Jellinger 《European journal of neurology》2009,16(9):e168-e168
996.
997.
Abstract: Background: The identification of an autoimmune mechanism for many patients with chronic idiopathic urticaria (CIU) was used as a rational for a controlled clinical trial of cyclosporine for adults with CIU not responsive to usual measures. That randomized placebo controlled clinical trial demonstrated clinical efficacy, acceptable safety, and a suggestion of inducing remission in such patients. Objective: To report our experience with cyclosporine in pediatric patients with CIU. Methods: Fifty‐four patients with CIU were referred to us during the period from 2000 through June of 2005. Seven of those, aged 9–16, failed therapy with high dose antihistamines even with the addition of alternate morning prednisone. Neoral brand of cyclosporine, 3 mg/kg/day divided b.i.d., was initiated in these patients. Cyclosporine serum concentrations, blood urea nitrogen (BUN), creatinine, and blood pressure were routinely monitored. Results: All had cessation of hives. This occurred after 1–4 weeks for six of the seven and 8 weeks for one. While some experienced relapses, all were eventually off of all medications and free of hives. None of the seven experienced any adverse effects. Conclusions: Our experience in children is consistent with a previous controlled clinical trial in adults and supports the efficacy and safety of cyclosporine for CIU. However, we recommend that it be reserved for those whose CIU that is resistant to conventional measures and that patients be carefully monitored with cyclosporine serum concentrations and measures of renal function. 相似文献
998.
999.
Several cases of relapsing attacks during which the ear becomes red and patients experience a burning sensation have been reported in the literature. This combination of symptoms has been described as ‘red ear syndrome’ (RES). We report on a 7‐year‐old boy who had episodes of reddening, swelling and a burning sensation in one ear with local hyperthermia persisting for 3 years. The differential diagnosis included RES and erythromelalgia, as isolated auricular variants of erythromelalgia have been described and the symptoms are difficult to distinguish from RES. In this report, we discuss the similarities and differences between RES and erythromelalgia. 相似文献
1000.