全文获取类型
收费全文 | 933篇 |
免费 | 382篇 |
国内免费 | 12篇 |
专业分类
耳鼻咽喉 | 4篇 |
儿科学 | 25篇 |
妇产科学 | 92篇 |
基础医学 | 72篇 |
口腔科学 | 5篇 |
临床医学 | 705篇 |
内科学 | 127篇 |
皮肤病学 | 11篇 |
神经病学 | 63篇 |
特种医学 | 42篇 |
外科学 | 29篇 |
综合类 | 26篇 |
预防医学 | 77篇 |
眼科学 | 1篇 |
药学 | 16篇 |
中国医学 | 1篇 |
肿瘤学 | 31篇 |
出版年
2023年 | 2篇 |
2022年 | 1篇 |
2021年 | 6篇 |
2020年 | 4篇 |
2019年 | 8篇 |
2018年 | 68篇 |
2017年 | 95篇 |
2016年 | 113篇 |
2015年 | 98篇 |
2014年 | 91篇 |
2013年 | 114篇 |
2012年 | 43篇 |
2011年 | 45篇 |
2010年 | 64篇 |
2009年 | 90篇 |
2008年 | 62篇 |
2007年 | 57篇 |
2006年 | 44篇 |
2005年 | 38篇 |
2004年 | 44篇 |
2003年 | 19篇 |
2002年 | 15篇 |
2001年 | 15篇 |
2000年 | 14篇 |
1999年 | 10篇 |
1998年 | 16篇 |
1997年 | 20篇 |
1996年 | 20篇 |
1995年 | 14篇 |
1994年 | 9篇 |
1993年 | 12篇 |
1992年 | 8篇 |
1991年 | 2篇 |
1990年 | 6篇 |
1989年 | 7篇 |
1988年 | 5篇 |
1987年 | 8篇 |
1986年 | 3篇 |
1985年 | 13篇 |
1984年 | 5篇 |
1983年 | 5篇 |
1982年 | 5篇 |
1981年 | 1篇 |
1980年 | 3篇 |
1979年 | 1篇 |
1978年 | 1篇 |
1977年 | 2篇 |
1975年 | 1篇 |
排序方式: 共有1327条查询结果,搜索用时 15 毫秒
991.
Anindita Majumdar Pranita D Kamble CM Badole BC Harinath 《Asian Pacific journal of tropical medicine》2010,3(5):356-359
ObjectiveTo evaluate inhouse developed SEVA TB peroxidase enzyme immunoassay using cocktail of mycobacterial excretory-secretory antigens (ES-31, ES-43 & EST-6) for antibody detection and their affinity purified antibodies for antigen detection in tuberculosis suspected patients.MethodsInhouse developed SEVA TB peroxidase enzyme immunoassay was evaluated prospectively in 73 suspected pulmonary and 46 extra-pulmonary tuberculosis patients during November 2008~March 2009 in a tertiary hospital located in rural area.ResultsAssay on prospective analysis showed 100% correlation of pulmonary tuberculosis (PTB) and extra-pulmonary tuberculosis (EPTB) acid fast bacilli positivity and antitubercular treatment in 11 cases. Thirty nine PTB and 12 EPTB cases showed negative for ELISA test and were also not given antitubercular therapy. However 30 PTB and 27 EPTB cases showing ELISA positivity were neither acid fast bacilli positive nor antitubercular therapy treated. These cases may possibly have dormant infection and need further diagnosis. In EPTB cases ELISA was observed to be more useful than AFB smear test.ConclusionsThis inhouse developed user-friendly peroxidase ELISA can be used as an adjunct test of smear microscopy or culture techniques for routine screening of patients suspected of PTB or EPTB. 相似文献
992.
The gastroenterologist must be alert to diagnosing parasitic diseases when collecting intestinal fluid samples or cytologies during endoscopy. Between 1979 and 1982, we identified nematodes in 10 endoscopic specimens. None were Strongyloides stercoralis. We emphasize the importance and technical aspects of distinguishing nonpathogenic nematodes from Strongyloides. 相似文献
993.
994.
Risk-taking behaviors among injecting drug users who obtain syringes from pharmacies, fixed sites, and mobile van needle exchanges 总被引:1,自引:0,他引:1
Ms. Cari L. Miller BC Dr. Mark Tyndall Dr. Patricia Spittal Ms. Kathy Li Dr. Anita Palepu Dr. Martin T. Schechter 《Journal of urban health》2002,79(2):257-265
Needle-exchange programs (NEPs) have been shown to be effective in reducing barm related to injection drug use and to act
as an important link between the injection drug using community and preventive/treatment services. Different needle-exchange
distribution methods may reach different subpopulations of injecting drug users (IDUs). We undertook this study to characterize
risk behaviors by primary source of clean needles accessed by IDUs in a city with pharmacy access and fixed and mobile exchange
programs. We hypothesized there would be a gradient of risk across the three types of distribution. Data were collected from
within the Vancouver Injection Drug Users Study (VIDUS), a prospective cohort study. Participants who primarily obtained clean
needles from pharmacies, fixed sites, or mobile exchange vans were compared using the Cochran-Armitage trend test to test
for trends in increasing risk behaviors across the three types of distribution. Ordinal multivariate regression was used to
adjust the associations for potential confounders. Results illustrate clear trends for increasing risk profiles from pharmacy
to fixed site to mobile exchange vans. Van users were generally at higher risk than fixed-site and pharmacy users. Independent
predictors of van use were fewer years injecting, difficulty finding needles, Aboriginal ethnicity, incarceration in the previous
6 months, and injecting cocaine daily. An important component of needle-exchange programs is outreach to access those who
are at highest risk. Use of distribution beyond fixed sites will improve such outreach, thereby increasing program effectiveness
and further preventing the transmission of blood-borne infections. 相似文献
995.
A middle-aged woman developed malabsorption and severe protein-calorie malnutrition after a near-total gastrectomy for a perforated gastric ulcer. A transbronchial lung biopsy showed pulmonary infection with Torulopsis glabrata. Improvement in the patient's nutritional status was followed by clearing of the pneumonia without the need for antifungal chemotherapy. 相似文献
996.
997.
Isolation and characterization of two hemolytic phenotypes of Vibrio damsela associated with a fatal wound infection. 总被引:6,自引:0,他引:6 下载免费PDF全文
Two hemolytic phenotypes of Vibrio damsela, isolated from the tissue of a patient with a fatal wound infection, were characterized. The patient had underlying disease, and the wound was associated with an injury inflicted during the handling of a catfish. The phenotypes were morphologically and biochemically similar except for their lecithinase, lipase, and hemolytic activities. When grown on rabbit blood agar, one phenotype (LZ) produced a large zone of hemolysis (10 mm) around the colony, whereas the other type (SZ) produced only a small zone (1 to 2 mm). On sheep blood agar, the differences in hemolytic activity were more subtle. By a modified CAMP test in which V. damsela was streaked perpendicularly to Staphylococcus aureus, it was determined that a factor elaborated by the LZ phenotype (but not the SZ phenotype) protected sheep erythrocytes from the hemolysis normally caused by S. aureus toxins. Cell-free filtrates of broth cultures of each phenotype had the same effects on erythrocytes as did the organisms themselves. 相似文献
998.
R Wessalowski H Schroten E Neuen-Jacob H Reichmann BC Melnik HG Lenard Th Voit 《Acta paediatrica (Oslo, Norway : 1992)》1994,83(1):93-98
Wessalowski R, Schroten H, Neuen-Jacob E, Reichmann H, Melnik BC, Lenard HG, Voit Th. Acta Paediatr 1994;83:93–8. Stockholm. ISSN 0803–5253
A four-year-old boy presented with hepatomegaly, vacuolized granulocytes (Jordans' anomaly) and slightly progressive myopathy as signs of multisystem triglyceride storage disease. The nine-year-old sister of the patient also showed Jordans' anomaly and early fatigability, but no overt weakness. Biochemical analysis revealed normal values for carnitines, carnitine palmityl transferase in serum and striated muscle, and β-oxidation enzymes in striated muscle. Distribution of non-membrane-bound lipids in granulocytes, fibroblasts, smooth muscle cells and striated muscle was compatible with Chanarin-Dorfman syndrome. In contrast to Chanarin-Dorfman syndrome, our patients lacked congenital ichthyosis. 相似文献
A four-year-old boy presented with hepatomegaly, vacuolized granulocytes (Jordans' anomaly) and slightly progressive myopathy as signs of multisystem triglyceride storage disease. The nine-year-old sister of the patient also showed Jordans' anomaly and early fatigability, but no overt weakness. Biochemical analysis revealed normal values for carnitines, carnitine palmityl transferase in serum and striated muscle, and β-oxidation enzymes in striated muscle. Distribution of non-membrane-bound lipids in granulocytes, fibroblasts, smooth muscle cells and striated muscle was compatible with Chanarin-Dorfman syndrome. In contrast to Chanarin-Dorfman syndrome, our patients lacked congenital ichthyosis. 相似文献
1000.