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51.
Tarib NA Seong TW Chuen KM Kun MS Ahmad M Kamarudin KH 《The European journal of prosthodontics and restorative dentistry》2012,20(1):35-39
This paper aims to evaluate the effect of splinting during implant impression. A master model with two fixtures at the sites of 45 and 47 was used. 20 impressions were made for all four techniques: (A) indirect; (B) direct, unsplinted; (C) direct, splinted; and (D) direct, splinted, sectioned, and re-splinted. Splinting was undertaken with autopolymerizing acrylic resin (AAR). Horizontal distance between fixtures was compared using a digital caliper. The difference in distance were analysed with one-way ANOVA. Group A showed a significantly lowest accuracy among all techniques (p < or = 0.05). There was no significant difference of accuracy among the groups using direct techniques (p > or = 0.05). Group D was more accurate compared to group B and C. We conclude that splinting of impression copings would be beneficial to obtain an accurate impression. 相似文献
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56.
Pei‐Ju Chien Jiann‐Horng Yeh Chwen‐Ming Shih Yu‐Mei Hsueh Mei‐Chieh Chen Hou‐Chang Chiu 《Artificial organs》2013,37(2):211-216
Plasmapheresis not only removes circulating antibodies but also modulates cellular immunity, including lymphocyte subsets. To investigate the effect of double‐filtration plasmapheresis (DFPP) on the ratio of lymphocyte subsets in patients with myasthenia gravis (MG), we examined the percentages of B‐cells, T‐cells, T helper (Th) cells, T suppressor (Ts) cells, natural killer (NK) cells, NKT cells, and Th/Ts ratio before and after a single DFPP session and after a course of DFPP. A total of 26 patients were recruited; their peripheral blood lymphocyte subsets were assayed using flow cytometry. After a single session of DFPP treatment, the percentages of T‐cells (P = 0.0200), Th cells (P = 0.0178), and the Th/Ts ratio (P = 0.0309) decreased significantly, whereas the percentage of NK cells (P = 0.0007) increased significantly. More importantly, after one course of DFPP treatment, the reduced clinical quantitative MG (QMG) score was correlated with the decrease of the percentage of T‐cells (r = 0.5005, P = 0.0092). Fourteen thymectomized MG patients had decreased percentages of T‐cells (P = 0.0304) and Th cells (P = 0.0444), whereas they had increased NK cells (P = 0.0197) after a single DFPP session. Here, transiently decreased percentages of T‐cells after the full DFPP course could enhance the effectiveness of plasmapheresis for MG patients. 相似文献
57.
Cheng NC Yu YC Tai HC Hsueh PR Chang SC Lai SY Yi WC Fang CT 《Clinical infectious diseases》2012,55(7):930-939
Background.?Necrotizing fasciitis (NF) is a rapidly progressive, life-threatening soft-tissue infection that is traditionally caused by group A Streptococcus (GAS) or mixed aerobic/anaerobic bacteria. Monomicrobial Klebsiella pneumoniae NF (KP-NF) has been reported since 1996 but has not yet been systematically studied. Methods.?We retrospectively studied consecutive NF cases treated at a university hospital in Taiwan during 1997-2010 and investigated the clinical characteristics and outcomes associated with monomicrobial KP-NF, using monomicrobial GAS-NF as a reference. We also analyzed the virulence gene profiles of the isolated K. pneumoniae strains. Results.?Of 134 NF cases, 88 were monomicrobial, of which the most common pathogens were GAS (n?=?16) and K. pneumoniae (n?=?15). Monomicrobial KP-NF entailed a moderate risk of limb loss (20% vs 25%; P?=?1.000) and high mortality (47% vs 19%; P?=?.135), and it was more likely to involve bacteremia (80% vs 31%; P?=?.011), concomitant distant abscesses (27% vs 0%; P?=?.043), and underlying immunocompromising conditions (100% vs 63%; P?=?.018), compared with GAS-NF. The isolated K. pneumoniae strains (n?=?10) were of capsular polysaccharides genotype K1 (n?=?4), K54/K20/K5 (n?=?4), K2 (n?=?1), and K16 (n?=?1). All strains carried rmpA, iucABCDiutA, and iroA. Genotype K1 strains had a significantly higher risk of concomitant distant abscesses, compared with non-K1 strains (75% vs 0%; P?=?.033). Conclusions.?K. pneumoniae has become a common pathogen of monomicrobial NF in Taiwan. Physicians treating patients with monomicrobial KP-NF should be aware of the risk of concomitant distant abscesses, particularly in cases caused by genotype K1. 相似文献
58.
Lee YS Maruyama M Chang PC Park HW Rhee KS Hsieh YC Hsueh CH Shen C Lin SF Hwang HS Yin H Knollmann BC Chen PS 《Heart rhythm》2012,9(7):1125-1132
59.
Steve W. N. Ueng Li‐Jen Yuan Song‐Shu Lin Chi‐Chien Niu Yi‐Sheng Chan I‐Chun Wang Chuen‐Yung Yang Wen‐Jer Chen 《Journal of orthopaedic research》2013,31(3):376-384
Heat shock proteins (HSPs), inflammatory cytokines, nitric oxide (NO), and localized hypoxia‐induced apoptosis are thought to be correlated to the degree of cartilage injury. We investigated the effect of hyperbaric oxygen (HBO) on (1) interleukin‐1β (IL‐1β)‐induced NO production and apoptosis of rabbit chondrocytes and (2) healing of articular cartilage defects. For the in vitro study, RT‐PCR and Western blotting were performed to detect mRNA and protein expressions of HSP70, inducible NO synthase (iNOS), and caspase 3 in IL‐1β‐treated chondrocytes. To clarify that the HSP70 was necessary for anti‐iNOS and anti‐apoptotic activity by HBO, we treated the cells with an HSP70 inhibitor, KNK437. For the in vivo study, cartilage defects were created in rabbits. The HBO group was exposed to 100% oxygen at 2.5 ATA for 1.5 h a day for 10 weeks. The control group was exposed to normal air. After sacrifice, specimen sections were sent for examination using a scoring system. Immunohistochemical analyses were performed to detect the expressions of iNOS, HSP70, and caspase 3. Our results suggested that HBO upregulated the mRNA and protein expressions of HSP70 and suppressed those of iNOS and caspase 3 in chondrocytes. KNK437 inhibited the HBO‐induced downregulation of iNOS and casapase 3 activities. The histological scores showed that HBO markedly enhanced cartilage repair. Immunohistostaining showed that HBO enhanced HSP70 expression and suppressed iNOS and caspase 3 expressions in chondrocytes. Accordingly, HBO treatment prevents NO‐induced apoptosis in articular cartilage injury via enhancement of the expression of heat shock protein 70. © 2012 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 31: 376–384, 2013 相似文献
60.
Chih‐Cheng Huang MD PhD Tai‐Lin Huang MD Hsuan‐Chih Hsu MD Hui‐Chun Chen MD Hsin‐Ching Lin MD Chih‐Yen Chien MD Fu‐Min Fang MD PhD Hsueh‐Wen Chang PhD Nai‐Wen Tsai MD PhD Wen‐Neng Chang MD Shu‐Fang Chen MD Tzu‐Kong Lin MD PhD Teng‐Yeow Tan MD Chuang‐Rung Chang PhD Hung‐Chen Wang MD Wei‐Che Lin MD PhD Cheng‐Hsien Lu MD MSc 《Muscle & nerve》2013,47(3):344-350