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排序方式: 共有1247条查询结果,搜索用时 15 毫秒
991.
992.
Tumor invasion to the arteries feeding the gallbladder as a novel risk factor for cholecystitis after metallic stent placement in distal malignant biliary obstruction 下载免费PDF全文
Yuko Sogabe Yuzo Kodama Hajime Honjo Ikuo Aoyama Yuya Muramoto Eri Koga Takafumi Yanaidani Munenori Kawai Teppei Yoshikawa Shimpei Matsumoto Astushi Matsumoto Yoshiharu Mori Chikage Ono Miyu Nishida Yoshihiro Nishida Takao Mikami Yasuhiro Matsunaga Yukiko Miyamoto Motoya Kitami Koji Nishikawa Masahiko Kondo Naoki Miyake Chiharu Kawanami Hiroshi Seno 《Digestive endoscopy》2018,30(3):380-387
993.
Nishikido N Matsuda K Fukuda E Motoki C Tsutaki M Kawakami Y Yuasa A Iijima M Tanaka M Hirata M Hojoh M Ikeda T Maeda K Miyoshi Y Arai S Mitsuhashi H 《Industrial health》2007,45(1):62-73
The objective of this study is to develop an available empowerment model for workplace health promotion (WHP) in small and medium-sized enterprises (SMEs) and to evaluate its applicability and feasibility. Semi-structured interviews with employers and workers in SMEs were conducted to assess their actual requirements for support. The structure of our new empowerment model was discussed and established through several rounds of focus group meetings with occupational safety and health researchers and practitioners on the basis of results of our interviews. We developed a new participatory and action-oriented empowerment model based on needs for support of employers and workers in SMEs. This new model consists of three originally developed tools: an action checklist, an information guidebook, and a book of good practices. As the facilitators, occupational health nurses (OHNs) from health insurance associations were trained to empower employers and workers using these tools. Approximately 80 SMEs (with less than 300 employees) were invited to participate in the model project. With these tools and continued empowerment by OHNs, employers and workers were able to smoothly work on WHP. This newly developed participatory and action-oriented empowerment model that was facilitated by trained OHNs appears to be both applicable and feasible for WHP in SMEs in Japan. 相似文献
994.
Yamazaki Y Satoh C Ishikawa M Notani K Nomura K Kitagawa Y 《Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics》2007,104(1):67-71
We report a juvenile case of diffuse sclerosing osteomyelitis of the mandible that showed a favorable response to pamidronate, a bisphosphonate derivative. Although conventional treatments had been ineffective for 5 years, pamidronate administration brought about conspicuous improvement both clinically and radiographically. Severe adverse reaction was not found except for low-grade fever and lassitude on the day following administration. During the course of the treatment, however, nonsuppurative osteomyelitis of the right humerus also occurred, leading to the established diagnosis of chronic recurrent multifocal osteomyelitis. Pamidronate therapy was again performed successfully with near disappearance of clinical symptoms. Both bone-specific alkaline phosphatase (bone formation marker) and pyridinoline cross-linked carboxyterminal telopeptide of type I collagen (bone resorption marker) showed a marked decrease with pamidronate therapy, suggesting that pamidronate is useful for the treatment of chronic recurrent multifocal osteomyelitis with inhibitory effect on bone turnover. 相似文献
995.
Meeting report: threats to human health and environmental sustainability in the pacific basin 下载免费PDF全文
Arnold RG Carpenter DO Kirk D Koh D Armour MA Cebrian M Cifuentes L Khwaja M Ling B Makalinao I Paz-Y-Miño C Peralta G Prasad R Singh K Sly P Tohyama C Woodward A Zheng B Maiden T 《Environmental health perspectives》2007,115(12):1770-1775
The coastal zone of the Pacific Rim is home for about one-third of the world's population. Disproportionate growth of Far Eastern economies has produced a disproportionate share of related environmental difficulties. As the region searches for acceptable compromises between growth and environmental quality, its influence on global environmental health is certain to increase. Consequences of global environmental change such as habitat alteration, storms, and sea level rise will be particularly acute among Pacific Rim nations. Adverse health effects from arsenic exposure in Pacific Rim nations have been used to justify drinking water standards in the United States and elsewhere. As global manufacturing in the Pacific Rim increases, the centroid of global air quality and waste management issues will shift further toward Far Eastern nations. The Eleventh International Conference of the Pacific Basin Consortium (PBC) was held in September 2005 in Honolulu, Hawaii. The purpose of the conference was to bring together individuals to discuss regional challenges to sustainable growth. The historic emphasis of the conference on hazardous wastes in relation to human health makes the PBC an ideal forum for discussing technical aspects of sustainable economic growth in the Pacific region. That role is reflected in the 2005 PBC conference themes, which included management of arsenic in potable waters, air quality, climate change, pesticides, mercury, and electronics industry waste-each with emphasis on relationships to human health. Arsenic management exemplifies the manner in which the PBC can focus interdisciplinary discussion in a single technical area. The conference program provided talks on arsenic toxicology, treatment technologies, management of arsenic-bearing residuals from water treatment, and the probable societal costs and benefits of arsenic management. 相似文献
996.
Kazuaki YAMAMOTO Hisashi ITO Shigeru FUKUTAKE Takashi ODO Tetsumasa KAMEI Toshio YAMAGUCHI Takaomi TAIRA 《Neurologia medico-chirurgica》2020,60(12):594
Transcranial magnetic resonance-guided focused ultrasound (FUS) therapy is a less invasive stereotactic treatment for tremor and other movement disorders. A sufficiently high temperature in the target brain tissue is crucial during ablation procedures for good outcomes. Therefore, maximizing the heating efficiency is critical in cases where high temperature cannot be achieved because of patient-related characteristics. However, a strategy to achieve the desired therapeutic temperature with FUS has not yet been established. This study aimed to investigate the procedural factors associated with heating efficiency in FUS. We retrospectively reviewed and analyzed data from patients who underwent FUS for ventralis intermedius (VIM) nucleus thalamotomy. In all, 30 consecutive patients were enrolled. 18 with essential tremor (ET), 11 with tremor-dominant Parkinson’s disease (TDPD), and 1 with Holmes tremor. Multivariate regression analysis showed that decline in heating efficiency was associated with lower skull density ratio (SDR) and a greater subtotal rise in temperature until the previous sonication. To maximize heating efficiency, the temperature increase should be set to the least value in the target alignment and verification phases, and subsequently should be increased sufficiently in the treatment phase. This strategy may be particularly beneficial in cases where high ablation temperatures cannot be achieved because of patient-related characteristics. Importantly, a broad patient population would benefit from this strategy as it could reduce the need for high energy to achieve therapeutic temperatures, thereby decreasing the risks of adverse events. 相似文献
997.
Yuki Yamashita Satoru Joshita Ayumi Sugiura Tomoo Yamazaki Hiroyuki Kobayashi Shun-ichi Wakabayashi Yosuke Yamada Soichiro Shibata Hideo Kunimoto Takanobu Iwadare Makiko Matsumura Chiharu Miyabayashi Taiki Okumura Sachie Ozawa Yuichi Nozawa Natsuko Kobayashi Michiharu Komatsu Naoyuki Fujimori Hiromi Saito Takeji Umemura 《Hepatology research》2021,51(9):933-942
998.
Tatsuhiko Yagihashi Chiharu Torii Reiko Takahashi Mikimasa Omori Rika Kosaki Hiroshi Yoshihashi Masahiro Ihara Yasuyo Minagawa‐Kawai Junichi Yamamoto Takao Takahashi Kenjiro Kosaki 《Congenital anomalies》2014,54(4):225-227
To reveal the relation between intellectual disability and the deleted intervals in Williams syndrome, we performed an array comparative genomic hybridization analysis and standardized developmental testing for 11 patients diagnosed as having Williams syndrome based on fluorescent in situ hybridization testing. One patient had a large 4.2‐Mb deletion spanning distally beyond the common 1.5‐Mb intervals observed in 10/11 patients. We formulated a linear equation describing the developmental age of the 10 patients with the common deletion; the developmental age of the patient with the 4.2‐Mb deletion was significantly below the expectation (developmental age = 0.51 × chronological age). The large deletion may account for the severe intellectual disability; therefore, the use of array comparative genomic hybridization may provide practical information regarding individuals with Williams syndrome. 相似文献
999.
1000.
The hypochlorite anion (OCl−), a reactive oxygen species (ROS), is an important microbicidal agent in the immune system. Accurate and selective detection of OCl− in environmental and biological samples by a fluorescent molecular sensor is an important subject. All previously reported sensors, however, have suffered from tedious multi-step synthesis for the sensors and the use of large amounts of organic solvents for the analysis. Herein, we report that a coumarin–dihydroperimidine dye prepared by facile condensation behaves as a fluorescent sensor for OCl− in 99% water. The sensor exhibits weak fluorescence, but OCl−-selective dehydrogenation of its dihydroperimidine unit creates a strong blue fluorescence. This turn-on fluorescence response facilitates selective and sensitive detection of OCl− in the physiological pH range. Ab initio calculation revealed that the fluorescence enhancement by OCl− is triggered by intramolecular proton transfer from the coumarin –OH to the imine nitrogen of the formed perimidine moiety.A coumarin–dihydroperimidine dye exhibits strong blue fluorescence by OCl−-selective dehydrogenation of the dihydroperimidine unit, and facilitates selective and sensitive fluorometric detection of OCl− in 99% water. 相似文献