全文获取类型
收费全文 | 314648篇 |
免费 | 62383篇 |
国内免费 | 14366篇 |
专业分类
耳鼻咽喉 | 3600篇 |
儿科学 | 7257篇 |
妇产科学 | 5679篇 |
基础医学 | 43373篇 |
口腔科学 | 9124篇 |
临床医学 | 42891篇 |
内科学 | 62025篇 |
皮肤病学 | 9991篇 |
神经病学 | 26130篇 |
特种医学 | 10688篇 |
外国民族医学 | 96篇 |
外科学 | 40019篇 |
综合类 | 34200篇 |
现状与发展 | 49篇 |
一般理论 | 67篇 |
预防医学 | 19260篇 |
眼科学 | 7945篇 |
药学 | 29542篇 |
164篇 | |
中国医学 | 11893篇 |
肿瘤学 | 27404篇 |
出版年
2024年 | 700篇 |
2023年 | 3546篇 |
2022年 | 8806篇 |
2021年 | 12700篇 |
2020年 | 13090篇 |
2019年 | 17659篇 |
2018年 | 17529篇 |
2017年 | 17725篇 |
2016年 | 18104篇 |
2015年 | 21310篇 |
2014年 | 23881篇 |
2013年 | 23574篇 |
2012年 | 21663篇 |
2011年 | 23260篇 |
2010年 | 20203篇 |
2009年 | 14432篇 |
2008年 | 14902篇 |
2007年 | 13846篇 |
2006年 | 13440篇 |
2005年 | 13306篇 |
2004年 | 9458篇 |
2003年 | 8485篇 |
2002年 | 7556篇 |
2001年 | 6875篇 |
2000年 | 6905篇 |
1999年 | 6766篇 |
1998年 | 3710篇 |
1997年 | 3725篇 |
1996年 | 2837篇 |
1995年 | 2622篇 |
1994年 | 2272篇 |
1993年 | 1519篇 |
1992年 | 2380篇 |
1991年 | 2067篇 |
1990年 | 1731篇 |
1989年 | 1510篇 |
1988年 | 1309篇 |
1987年 | 1204篇 |
1986年 | 970篇 |
1985年 | 791篇 |
1984年 | 519篇 |
1983年 | 401篇 |
1982年 | 239篇 |
1981年 | 222篇 |
1980年 | 200篇 |
1979年 | 260篇 |
1978年 | 153篇 |
1977年 | 125篇 |
1976年 | 110篇 |
1974年 | 121篇 |
排序方式: 共有10000条查询结果,搜索用时 4 毫秒
91.
92.
Richard Kim Elaine Tan Emily Wang Amit Mahipal Dung-Tsa Chen Biwei Cao Fadzai Masawi Cindy Machado James Yu Dae Won Kim 《The oncologist》2020,25(12):e1893-e1899
Lessons Learned
- The combination of trametinib and sorafenib has an acceptable safety profile, albeit at doses lower than approved for monotherapy.
- Maximum tolerated dose is trametinib 1.5 mg daily and sorafenib 200 mg twice daily.
- The limited anticancer activity observed in this unselected patient population does not support further exploration of trametinib plus sorafenib in patients with hepatocellular carcinoma.
93.
Dana Franzen-Klein Mark Jankowski Charlotte L. Roy Hoa Nguyen-Phuc Da Chen Lorin Neuman-Lee 《Journal of toxicology and environmental health. Part A》2020,83(2):45-65
ABSTRACTDomestic chickens (Gallus gallus domesticus) were exposed to imidacloprid by gavage once daily for 7 consecutive days at 0, 0.03, 0.34, 3.42, 10.25, and 15.5 mg/kg/day (n = 20 per group; 5 6-week-old males, 5 6-week-old females, 5 9-week-old males, and 5 9-week-old females). The severity and duration of neurobehavioral abnormalities were recorded. Components of the innate and adaptive immune system were assessed with 7 standard functional assays. Temporary neurobehavioral abnormalities were observed in a dose-dependent manner, including muscle tremors, ataxia, and depressed mentation. Based upon mean clinical severity scores, the no observed adverse effect level (NOAEL) was 3.42 mg/kg/day, and the lowest observed adverse effect level (LOAEL) was 10.25 mg/kg/day. The effective dose value for the presence of any neurobehavioral abnormalities in 50% of the test group (ED50) was 4.62 ± 0.98 mg/kg/day. The ED50 for an adjusted score that included both severity and duration of neurobehavioral abnormalities was 11.24 ± 9.33 mg/kg/day. These ED50 values are equivalent to a 1 kg bird ingesting 29 or 70 imidacloprid treated soybean seeds respectively. Immunotoxicity was not documented, possible causes include the assays were insensitive, relevant immune functions were not examined, or imidacloprid is not immunotoxic at this dosing schedule in this species. Neurobehavioral abnormalities were a more sensitive indicator of the sublethal effects of imidacloprid than immunotoxicity. 相似文献
94.
95.
96.
A mixed‐method study of effects of a therapeutic play intervention for children on parental anxiety and parents' perceptions of the intervention
下载免费PDF全文
![点击此处可从《Journal of advanced nursing》网站下载免费的PDF全文](/ch/ext_images/free.gif)
97.
98.
99.
Shengxuan Cao Chen Wang Xin Ma Xu Wang Jiazhang Huang Chao Zhang Li Chen Xiang Geng Kan Wang 《Journal of orthopaedic research》2019,37(8):1860-1867
Patients with mechanic ankle instability experience increased tibiotalar and subtalar joint laxity. However, in vivo joint kinematics in functional ankle instability (FAI) patients and lateral ankle sprain (LAS) copers, especially during dynamic activities, are poorly understood. Ten FAI patients, 10 LAS copers, and 10 healthy controls were included in this study. A dual fluoroscopic imaging system was used to analyze the tibiotalar and subtalar joint kinematics during stair descent. Five key poses of stair descent were analyzed. Kinematic data from six degrees of freedom were calculated utilizing a solid modeling software. The range of motion and joint positions in each degree of freedom were compared among the three groups. The tibiotalar joints of FAI patients and LAS copers were significantly more inverted than those of healthy controls during the foot strike (p = 0.016, = 0.264). The subtalar joints of FAI patients were significantly more anteriorly translated (pose 2, p = 0.003, = 0.352; pose 3, p < 0.001, = 0.454; pose 4, p = 0.004, = 0.334), inverted (pose 4, p = 0.027, = 0.234; pose 5,p = 0.034, = 0.221), and externally rotated (pose 4, p = 0.037, = 0.217; pose 5; p = 0.004, = 0.331) than those of healthy controls during the mid‐stance and the heel off. The FAI patients showed excessive tibiotalar inversion and subtalar joint hypermobility during stair descent. Meanwhile, the LAS copers maintained subtalar joint stability, and only showed excessive tibiotalar inversion in foot strike. These data provide insight into the mechanisms behind the development of FAI after initial LAS. © 2019 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 37:1860–1867, 2019 相似文献
100.